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Systemic lupus erythematosusa compan...

Gordon, Caroline, (1956-)

Systemic lupus erythematosusa companion to Rheumatology /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Systemic lupus erythematosus[edited by] George Tsokos, Caroline Gordon, Josef Smolen.
Reminder of title:	a companion to Rheumatology /
other author:	Tsokos, George C.
Published:	Philadelphia :Mosby Elsevier,c2007.
Description:	xv, 586 p. :ill. (some col.) ;27 cm.
Subject:	Systemic lupus erythematosus.
Online resource:	An electronic book accessible through the World Wide Web; click for information
ISBN:	9780323044349

Systemic lupus erythematosusa companion to Rheumatology /
Systemic lupus erythematosusa companion to Rheumatology /[electronic resource] :[edited by] George Tsokos, Caroline Gordon, Josef Smolen. - 1st ed. - Philadelphia :Mosby Elsevier,c2007. - xv, 586 p. :ill. (some col.) ;27 cm.

Includes bibliographical references and index.

Epidemiology and Diagnosis -- -- 1. Epidemiology -- 2. Disease Activity Measures -- 3. Disease Outcome -- 4. Quality of Life and Economic Aspects -- Pathogenesis -- 1. Overview of the Pathogenesis of SLE -- 2. Genetics -- 3. Hormones -- 4. Immunoregulation b6 s T Cells, B cells, and cytokines. -- 5. Cell Surface Receptors ostimulation/BAFF/FcgR/TLRs) -- 6. Dendritic Cells -- 7. Apoptosis -- 8. Structure and Origin of Autoantibodies -- 9. Animal Models -- 10. Genetics of murine lupus -- 11. Infection and autoimmunity -- Mechanisms of Tissue Damage -- 1. Complement -- 2. Immune complexes -- 3. Antibodies -- a. ANA and standardization of antibody techniques -- b. Anti-DNA -- c. Anti-splicesomosal ab -- d. Anti-Ro/La -- e. Anti-Histone -- f. APL -- g. Anti-neuronal -- 4. PMNs -- 5. Mechanisms of renal damage -- 6. Mechanisms of vascular damage -- 7. Nitric Oxide -- Clinical Aspects of the Disease -- 1. Constitutional Symptoms and Fatigue -- 2. Skin -- 3. Kidney -- 4. Heart -- 5. Lung -- 6. GI/liver/pancreas -- 7. Infections -- 8. Blood (anti-phospholipid syndrome) -- 9. Nervous System -- 10. Overlap Syndromes -- 11. Ophthalmic Manifestations -- 12. Pregnancy -- 13. Fertility -- 14. Neo-natal lupus -- 15. Hereditary and Malignant Lupus-like Diseases -- Treatment of the Disease -- 1. Non-Steroidals b6 s Anti-Malarials and Statins -- 2. Steroid Treatment -- 3. Cytotoxic Drug Treatment including M.M.F -- 4. PAPS -- 5. New Treatments.

This new companion to Hochberg et al.'s Rheumatology masterwork provides new insights into the causes, detection and therapy of this challenging disease. In this state-of-the-art resource, you'll find b1 sone stop' coverage of all the latest scientific and clinical developments in SLE: new concepts in epidemiology, disease activity measures and outcomes; new concepts in immunoregulation, genetic and pathogenic mechanisms; new understanding and novel presentation of the processes of tissue/organ damage; comprehensive coverage of clinical features; and the very latest concepts in treatment. Provides the very latest understanding of the pathogenesis of SLE. Distills current understanding of the cellular, molecular, genetic and environmental factors that instigate and drive the disease.Includes comprehensive coverage of clinical features, including fatigue, organ system manifestations, overlap syndromes, infections, and more.Conveys the very latest understanding of mechanisms of tissue damage, including immune complexes, antibodies, and other mechanisms that lead to organ damage.Contains expert discussion of processes that are responsible for tissue injury - a hallmark of this text.Incorporates the latest treatment modalities, including steroids and non-steroidals, cytotoxic drug treatment, PAP's, and therapies on the horizon.Discusses the latest treatment options on disease modifying or disease controlling agents.

Electronic reproduction.
Amsterdam :
Elsevier Science & Technology,
2009.

Mode of access: World Wide Web.

ISBN: 9780323044349

Source: 110018:110066Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

317587
Systemic lupus erythematosus.
Index Terms--Genre/Form:

214472
Electronic books.

LC Class. No.: RC924.5.L85 / S967 2007

Dewey Class. No.: 616.7/7

National Library of Medicine Call No.: 2007 C-175

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504 $a Includes bibliographical references and index.
505 0 $a Epidemiology and Diagnosis -- -- 1. Epidemiology -- 2. Disease Activity Measures -- 3. Disease Outcome -- 4. Quality of Life and Economic Aspects -- Pathogenesis -- 1. Overview of the Pathogenesis of SLE -- 2. Genetics -- 3. Hormones -- 4. Immunoregulation b6 s T Cells, B cells, and cytokines. -- 5. Cell Surface Receptors ostimulation/BAFF/FcgR/TLRs) -- 6. Dendritic Cells -- 7. Apoptosis -- 8. Structure and Origin of Autoantibodies -- 9. Animal Models -- 10. Genetics of murine lupus -- 11. Infection and autoimmunity -- Mechanisms of Tissue Damage -- 1. Complement -- 2. Immune complexes -- 3. Antibodies -- a. ANA and standardization of antibody techniques -- b. Anti-DNA -- c. Anti-splicesomosal ab -- d. Anti-Ro/La -- e. Anti-Histone -- f. APL -- g. Anti-neuronal -- 4. PMNs -- 5. Mechanisms of renal damage -- 6. Mechanisms of vascular damage -- 7. Nitric Oxide -- Clinical Aspects of the Disease -- 1. Constitutional Symptoms and Fatigue -- 2. Skin -- 3. Kidney -- 4. Heart -- 5. Lung -- 6. GI/liver/pancreas -- 7. Infections -- 8. Blood (anti-phospholipid syndrome) -- 9. Nervous System -- 10. Overlap Syndromes -- 11. Ophthalmic Manifestations -- 12. Pregnancy -- 13. Fertility -- 14. Neo-natal lupus -- 15. Hereditary and Malignant Lupus-like Diseases -- Treatment of the Disease -- 1. Non-Steroidals b6 s Anti-Malarials and Statins -- 2. Steroid Treatment -- 3. Cytotoxic Drug Treatment including M.M.F -- 4. PAPS -- 5. New Treatments.
520 $a This new companion to Hochberg et al.'s Rheumatology masterwork provides new insights into the causes, detection and therapy of this challenging disease. In this state-of-the-art resource, you'll find b1 sone stop' coverage of all the latest scientific and clinical developments in SLE: new concepts in epidemiology, disease activity measures and outcomes; new concepts in immunoregulation, genetic and pathogenic mechanisms; new understanding and novel presentation of the processes of tissue/organ damage; comprehensive coverage of clinical features; and the very latest concepts in treatment. Provides the very latest understanding of the pathogenesis of SLE. Distills current understanding of the cellular, molecular, genetic and environmental factors that instigate and drive the disease.Includes comprehensive coverage of clinical features, including fatigue, organ system manifestations, overlap syndromes, infections, and more.Conveys the very latest understanding of mechanisms of tissue damage, including immune complexes, antibodies, and other mechanisms that lead to organ damage.Contains expert discussion of processes that are responsible for tissue injury - a hallmark of this text.Incorporates the latest treatment modalities, including steroids and non-steroidals, cytotoxic drug treatment, PAP's, and therapies on the horizon.Discusses the latest treatment options on disease modifying or disease controlling agents.
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