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MRI contrast agentsfrom molecules to...

Laurent, Sophie.

MRI contrast agentsfrom molecules to particles /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	MRI contrast agentsby Sophie Laurent ... [et al.].
其他題名:	from molecules to particles /
其他作者:	Laurent, Sophie.
出版者:	Singapore :Springer Singapore :2017.
面頁冊數:	vii, 125 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
標題:	Contrast media (Diagnostic imaging)
電子資源:	http://dx.doi.org/10.1007/978-981-10-2529-7
ISBN:	9789811025297$q(electronic bk.)

MRI contrast agentsfrom molecules to particles /
MRI contrast agentsfrom molecules to particles /[electronic resource] :by Sophie Laurent ... [et al.]. - Singapore :Springer Singapore :2017. - vii, 125 p. :ill., digital ;24 cm. - SpringerBriefs in applied sciences and technology,2191-530X. - SpringerBriefs in applied sciences and technology..

Nanomaterials in medicine -- Magnetic properties (diamagnetism, paramagnetism, ferromagnetism, ferrimagnetism, antiferromagnetism, superparamagnetism) -- Imaging probes -- Magnetic resonance imaging (MRI) -- Bases of MRI -- MRI contrast agents -- Paramagnetic gadolinium complexes -- Superparamagnetic iron oxide nanoparticles -- Synthesis of magnetic nanoparticles -- Stabilization of magnetic nanoparticles -- Physico-chemical characterization of nanoparticles -- MRI applications -- Conclusions.

This book describes the multiple aspects of (i) preparation of the magnetic core, (ii) the stabilization with different coatings, (iii) the physico-chemical characterization and (iv) the vectorization to obtain specific nanosystems. Several bio-applications are also presented in this book. In the early days of Magnetic Resonance Imaging (MRI), paramagnetic ions were proposed as contrast agents to enhance the diagnostic quality of MR images. Since then, academic and industrial efforts have been devoted to the development of new and more efficient molecular, supramolecular and nanoparticular systems. Old concepts and theories, like paramagnetic relaxation, were revisited and exploited, leading to new scientific tracks. With their high relaxivity payload, the superparamagnetic nanoparticles are very appealing in the context of molecular imaging but challenges are still numerous: absence of toxicity, specificity, ability to cross the biological barriers, etc.

ISBN: 9789811025297$q(electronic bk.)

Standard No.: 10.1007/978-981-10-2529-7doiSubjects--Topical Terms:

379450
Contrast media (Diagnostic imaging)

LC Class. No.: RC78.7.C65

Dewey Class. No.: 616.0754

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520 $a This book describes the multiple aspects of (i) preparation of the magnetic core, (ii) the stabilization with different coatings, (iii) the physico-chemical characterization and (iv) the vectorization to obtain specific nanosystems. Several bio-applications are also presented in this book. In the early days of Magnetic Resonance Imaging (MRI), paramagnetic ions were proposed as contrast agents to enhance the diagnostic quality of MR images. Since then, academic and industrial efforts have been devoted to the development of new and more efficient molecular, supramolecular and nanoparticular systems. Old concepts and theories, like paramagnetic relaxation, were revisited and exploited, leading to new scientific tracks. With their high relaxivity payload, the superparamagnetic nanoparticles are very appealing in the context of molecular imaging but challenges are still numerous: absence of toxicity, specificity, ability to cross the biological barriers, etc.
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