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3D cell-based biosensors in drug dis...

Kisaalita, William Ssempa, (1953-)

3D cell-based biosensors in drug discovery programsmicrotissue engineering for high throughput screening /

Record Type:	Electronic resources : Monograph/item
Title/Author:	3D cell-based biosensors in drug discovery programsWilliam S. Kisaalita.
Reminder of title:	microtissue engineering for high throughput screening /
Author:	Kisaalita, William Ssempa,
Published:	Boca Raton [Fla.] :CRC Press,2010.
Description:	466 p.
Subject:	Biosensors.
Online resource:	Distributed by publisher. Purchase or institutional license may be required for access.
ISBN:	9781420073508 (e-book : PDF)

3D cell-based biosensors in drug discovery programsmicrotissue engineering for high throughput screening /
Kisaalita, William Ssempa,1953-

3D cell-based biosensors in drug discovery programsmicrotissue engineering for high throughput screening /[electronic resource] :William S. Kisaalita. - Boca Raton [Fla.] :CRC Press,2010. - 466 p.

Includes bibliographical references and index.

(Publisher-supplied data) Biosensors and Bioassays -- Target-Driven Drug Discovery -- Comparative Genomics and Proteomics -- Comparative Structure and Function -- Chemical Microenvironmental Factors -- Spatial and Temporal Microenvironmental Factors -- Material Physical Property and Force Microenvironmental Factors -- Proteomics as a Promising Tool in the Search for 3D Biomarkers -- Readout Present and Near Future -- Ready-to-Use Commercial 3D Plates -- Challenges to Adopting 3D Cultures in HTS Programs -- Cases for 3D Cultures in Drug Discovery -- Ideal Case Study Design.

"This book is based upon cutting-edge research conducted in the authors lab (Cellular Bioengineering), which over the past decade has developed a number of sophisticated techniques to facilitate use of 3D cell based assays or biosensors. This book uses data from peer-reviewed publications to conclusively justify use of 3D cell cultures in cell-based biosensors (assays) for (HTS). The majority of assays performed in accelerated drug discovery processes are biochemical in nature, but there is a growing demand for live cell-based assays. Unlike biochemical ones, cellular assays are functional approximations of in vivo biological conditions and can provide more biologically relevant information"--Provided by publisher.

Mode of access: World Wide Web.

ISBN: 9781420073508 (e-book : PDF)Subjects--Topical Terms:

188824
Biosensors.
Index Terms--Genre/Form:

214472
Electronic books.

3D cell-based biosensors in drug discovery programsmicrotissue engineering for high throughput screening /
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100 1 $a Kisaalita, William Ssempa, $d 1953- $3 487209
245 1 0 $a 3D cell-based biosensors in drug discovery programs $h [electronic resource] : $b microtissue engineering for high throughput screening / $c William S. Kisaalita.
260 $a Boca Raton [Fla.] : $b CRC Press, $c 2010.
300 $a 466 p.
504 $a Includes bibliographical references and index.
505 8 $a (Publisher-supplied data) Biosensors and Bioassays -- Target-Driven Drug Discovery -- Comparative Genomics and Proteomics -- Comparative Structure and Function -- Chemical Microenvironmental Factors -- Spatial and Temporal Microenvironmental Factors -- Material Physical Property and Force Microenvironmental Factors -- Proteomics as a Promising Tool in the Search for 3D Biomarkers -- Readout Present and Near Future -- Ready-to-Use Commercial 3D Plates -- Challenges to Adopting 3D Cultures in HTS Programs -- Cases for 3D Cultures in Drug Discovery -- Ideal Case Study Design.
520 $a "This book is based upon cutting-edge research conducted in the authors lab (Cellular Bioengineering), which over the past decade has developed a number of sophisticated techniques to facilitate use of 3D cell based assays or biosensors. This book uses data from peer-reviewed publications to conclusively justify use of 3D cell cultures in cell-based biosensors (assays) for (HTS). The majority of assays performed in accelerated drug discovery processes are biochemical in nature, but there is a growing demand for live cell-based assays. Unlike biochemical ones, cellular assays are functional approximations of in vivo biological conditions and can provide more biologically relevant information"--Provided by publisher.
530 $a Also available in print edition.
538 $a Mode of access: World Wide Web.
650 0 $a Biosensors. $3 188824
650 0 $a High throughput screening (Drug development) $3 301838
650 0 $a Pharmaceutical biotechnology. $3 189023
655 7 $a Electronic books. $2 local. $3 214472
776 1 $z 9781420073492
856 4 0 $u http://marc.crcnetbase.com/isbn/9781420073508 $q application/PDF $z Distributed by publisher. Purchase or institutional license may be required for access.