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Foundations of structural biology

Banaszak, Leonard.

Foundations of structural biology

Record Type:	Electronic resources : Monograph/item
Title/Author:	Foundations of structural biologyLeonard J. Banaszak.
Author:	Banaszak, Leonard.
Published:	San Diego, Calif. :Academic,c2000.
Description:	xi, 168 p. :ill. ;28 cm.
Subject:	DNAStructure.
Online resource:	An electronic book accessible through the World Wide Web; click for information
ISBN:	9780120777006

Foundations of structural biology
Banaszak, Leonard.

Foundations of structural biology[electronic resource] /Leonard J. Banaszak. - San Diego, Calif. :Academic,c2000. - xi, 168 p. :ill. ;28 cm.

Includes bibliographical references and index.

Introduction to Protein Structure. -- Solid State and Solution Methods for Determining Biological Macromolecular Structure. -- Crystallographic Coordinates and Stereodrawings. -- Properties of Biomacromolecules in the Crystalline State. -- Quaternary Structure of Proteins. -- Secondary Structure of Proteins. -- Domains and Super-secondary Structure. -- Conformational States in Crystal and NMR Structures. -- Hydrogen Bonds and Water Molecules in Crystalline Proteins. -- Protein and Nucleic Acid Complexes. -- Metal Ions Bound to Proteins. -- Lipid Protein Interactions.

Imagine trying to understand an engine without visualizing its moving parts. Biological processes involve far more complex chemical reactions and components than any engine. Furthermore, the parts work together to do many more functions than an engine which sole task is to turn a shaft. Understanding the implications of the three-dimensional coordinates for a molecule with several thousand atoms requires an understanding of, and practice with, 3D imaging. For many biologists, this means acquiring a whole new set of skills. Foundations of Structural Biology is aimed at helping the reader develop visualization skills for protein or DNA segments, while also describing the fundamental principles underlying the organization and interaction between these complex molecules. Key Features * Explains how to use coordinate databases and atomic coordinates of biological macromolecules * Teaches the skills of stereoviewing * Contains computer-generated stereographics * Describes the principles of symmetry and handedness in proteins and DNA * Introduces metal and lipid binding proteins and DNA-protein interactions * Explains the principles involved in understanding secondary and quaternary structure * Includes coverage of protein-metal, protein-nucleic acid, and protein-lipid interactions.

Electronic reproduction.
Amsterdam :
Elsevier Science & Technology,
2007.

Mode of access: World Wide Web.

ISBN: 9780120777006

Source: 89027:89027Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

225521
DNA
--Structure.Index Terms--Genre/Form:

214472
Electronic books.

LC Class. No.: QP624.5.S78 / B36 2000eb

Dewey Class. No.: 572.8/633

National Library of Medicine Call No.: 2000 F-375

Foundations of structural biology
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037 $a 89027:89027 $b Elsevier Science & Technology $n http://www.sciencedirect.com
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100 1 $a Banaszak, Leonard. $3 501786
245 1 0 $a Foundations of structural biology $h [electronic resource] / $c Leonard J. Banaszak.
260 $a San Diego, Calif. : $b Academic, $c c2000.
300 $a xi, 168 p. : $b ill. ; $c 28 cm.
504 $a Includes bibliographical references and index.
505 0 $a Introduction to Protein Structure. -- Solid State and Solution Methods for Determining Biological Macromolecular Structure. -- Crystallographic Coordinates and Stereodrawings. -- Properties of Biomacromolecules in the Crystalline State. -- Quaternary Structure of Proteins. -- Secondary Structure of Proteins. -- Domains and Super-secondary Structure. -- Conformational States in Crystal and NMR Structures. -- Hydrogen Bonds and Water Molecules in Crystalline Proteins. -- Protein and Nucleic Acid Complexes. -- Metal Ions Bound to Proteins. -- Lipid Protein Interactions.
520 $a Imagine trying to understand an engine without visualizing its moving parts. Biological processes involve far more complex chemical reactions and components than any engine. Furthermore, the parts work together to do many more functions than an engine which sole task is to turn a shaft. Understanding the implications of the three-dimensional coordinates for a molecule with several thousand atoms requires an understanding of, and practice with, 3D imaging. For many biologists, this means acquiring a whole new set of skills. Foundations of Structural Biology is aimed at helping the reader develop visualization skills for protein or DNA segments, while also describing the fundamental principles underlying the organization and interaction between these complex molecules. Key Features * Explains how to use coordinate databases and atomic coordinates of biological macromolecules * Teaches the skills of stereoviewing * Contains computer-generated stereographics * Describes the principles of symmetry and handedness in proteins and DNA * Introduces metal and lipid binding proteins and DNA-protein interactions * Explains the principles involved in understanding secondary and quaternary structure * Includes coverage of protein-metal, protein-nucleic acid, and protein-lipid interactions.
533 $a Electronic reproduction. $b Amsterdam : $c Elsevier Science & Technology, $d 2007. $n Mode of access: World Wide Web. $n System requirements: Web browser. $n Title from title screen (viewed on Aug. 2, 2007). $n Access may be restricted to users at subscribing institutions.
650 0 $a DNA $x Structure. $3 225521
650 0 $a Proteins $x Structure. $3 194956
650 0 $a DNA-binding protein interactions. $3 501787
650 0 $a Three-dimensional imaging in biology. $3 281422
650 1 2 $a DNA $x chemistry. $3 501788
650 2 2 $a DNA-Binding Proteins $x metabolism. $3 501789
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650 4 $a DNA-protein interactions. $3 501790
650 1 7 $a Macromoleculen. $2 gtt $3 501791
650 1 7 $a Ruimtelijke structuur. $2 gtt $3 501792
650 1 7 $a Kristallografie. $2 gtt $3 501793
650 1 7 $a Chemische structuur. $2 gtt $3 251415
655 4 $a Electronic books. $2 local. $3 214472
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856 4 0 $3 ScienceDirect $u http://www.sciencedirect.com/science/book/9780120777006 $z An electronic book accessible through the World Wide Web; click for information
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