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Comparative toxicogenomics

Record Type:	Electronic resources : Monograph/item
Title/Author:	Comparative toxicogenomicsedited by Christer Hogstrand and Peter Kille.
other author:	Hogstrand, Christer.
Published:	Amsterdam ;Elsevier,2008.
Description:	1 online resource (xxi, 321 p., [7] p. of plates) :ill.
Subject:	Genetic toxicology.
Online resource:	http://www.sciencedirect.com/science/book/9780444532749
ISBN:	9780444532749

Comparative toxicogenomics
Comparative toxicogenomics[electronic resource] /edited by Christer Hogstrand and Peter Kille. - 1st ed. - Amsterdam ;Elsevier,2008. - 1 online resource (xxi, 321 p., [7] p. of plates) :ill. - Advances in experimental biology,1872-2423. - Advances in experimental biology..

Includes bibliographical references and indexes.

Joseph R. Shaw, Dartmouth College: 'Daphnia Toxicogenomics' -- -- Professor Joseph Lunec and Dr. Eugene Halligan, King's College London: 'Human Toxicogenomics' -- -- Jake Bundy and Jeremy Nicholson, Imperial College: "Metabolomics and Toxicogenomics" -- -- Chris Vulpe, University of California, Berkely: "Model Organisms of Environmental Toxicogenomics (Ecotoxicological model species -- Daphnia, fathead minnow and zebrafish)" -- -- David Spurgeon, CEH Monks Wood: "Non-model organism Toxicogenomics or Earthworm Toxicogenomics" -- -- Charles Tyler, Exeter: "Application of Toxicogenomics for study of endocrine disruption in fish" -- -- Jason Snape, Astra-Zeneca Brixham Environmental Laboratories: "Microbial Toxicogenomics" -- -- Jonathan Freedman, NIEHS: "Comparative Toxicogenomics."

Toxicogenomics analyses the activity of a particular toxin or chemical substance on living tissue based upon a profiling of its known effects on genetic material. Toxicogenomics is important because it may enhance understanding of mechanisms of toxicity, cellular defence systems, and drug action. If this technique is proven to work, it could be used in a similar way for toxicology and toxin-determination to DNA-testing in the forensic identification of individuals. Comparative Toxicogenomics provides a timely overview of current achievements and future areas of development including a review of some of the first really fruitful studies made in this area. * Provides a review of some of the first really fruitful studies made in this area. * Covers different organisms ranging from humans to model species and environmental sentinels so researchers can see how this technique has been used across different organisms and compare the results of each. * The chapters transect research interests from identification of toxic action to environmental monitoring providing a broad view of the area increasing its attractiveness to researchers working in a variety of specialties.

ISBN: 9780444532749

Source: 154196:154356Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

188807
Genetic toxicology.
Index Terms--Genre/Form:

214472
Electronic books.

LC Class. No.: RA1224.3 / .C64 2008eb

Dewey Class. No.: 616.042

Comparative toxicogenomics
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245 0 0 $a Comparative toxicogenomics $h [electronic resource] / $c edited by Christer Hogstrand and Peter Kille.
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260 $a Amsterdam ; $a Boston : $b Elsevier, $c 2008.
300 $a 1 online resource (xxi, 321 p., [7] p. of plates) : $b ill.
490 1 $a Advances in experimental biology, $x 1872-2423
504 $a Includes bibliographical references and indexes.
505 0 $a Joseph R. Shaw, Dartmouth College: 'Daphnia Toxicogenomics' -- -- Professor Joseph Lunec and Dr. Eugene Halligan, King's College London: 'Human Toxicogenomics' -- -- Jake Bundy and Jeremy Nicholson, Imperial College: "Metabolomics and Toxicogenomics" -- -- Chris Vulpe, University of California, Berkely: "Model Organisms of Environmental Toxicogenomics (Ecotoxicological model species -- Daphnia, fathead minnow and zebrafish)" -- -- David Spurgeon, CEH Monks Wood: "Non-model organism Toxicogenomics or Earthworm Toxicogenomics" -- -- Charles Tyler, Exeter: "Application of Toxicogenomics for study of endocrine disruption in fish" -- -- Jason Snape, Astra-Zeneca Brixham Environmental Laboratories: "Microbial Toxicogenomics" -- -- Jonathan Freedman, NIEHS: "Comparative Toxicogenomics."
520 $a Toxicogenomics analyses the activity of a particular toxin or chemical substance on living tissue based upon a profiling of its known effects on genetic material. Toxicogenomics is important because it may enhance understanding of mechanisms of toxicity, cellular defence systems, and drug action. If this technique is proven to work, it could be used in a similar way for toxicology and toxin-determination to DNA-testing in the forensic identification of individuals. Comparative Toxicogenomics provides a timely overview of current achievements and future areas of development including a review of some of the first really fruitful studies made in this area. * Provides a review of some of the first really fruitful studies made in this area. * Covers different organisms ranging from humans to model species and environmental sentinels so researchers can see how this technique has been used across different organisms and compare the results of each. * The chapters transect research interests from identification of toxic action to environmental monitoring providing a broad view of the area increasing its attractiveness to researchers working in a variety of specialties.
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