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Advances in medicinal chemistry.Volume 5

Dax, S. L.

Advances in medicinal chemistry.Volume 5

Record Type:	Electronic resources : Monograph/item
Title/Author:	Advances in medicinal chemistry.
other author:	Reitz, A. B.
Published:	[S.l.] :Elsevier Science,2000.
Description:	1 v.
Subject:	Pharmaceutical chemistry.
Online resource:	http://www.sciencedirect.com/science/book/9780762305933
ISBN:	9780762305933

Advances in medicinal chemistry.Volume 5
Advances in medicinal chemistry.Volume 5[electronic resource]. - [S.l.] :Elsevier Science,2000. - 1 v.

Preface. Immunophilins: the next generation. Discovery of ABT-594 and related neuronal nicotinic acetylcholine receptor modulators as analgesic agents: medicinal chemistry and biology. Discovery and preclinical evaluation of novel dopamine partial agonists as antipsychotic agents. Nonpeptide inhibitors of HIV protease.

Volume 5 of Advances in Medicinal Chemistry contains four intriguing and detailed accounts of the close interface between synthetic chemistry, structure-activity relationships, biochemistry, and pharmacology. In Chapter 1, there is a comprehensive survey of the immunophilin area specifically focussing on neuroregenerative applications in the central nervous system. In Chapter 2, there is an overview of the development of a potent analgesic compound that works via modulation of neuronal nicotinic acetylcholine receptors. In Chapter 3, there is a description of dopamine D-2 autoreceptor partial agonists as potential therapy for the treatment of schizophrenia. In Chapter 4, there is a summary of the successful program in which potent non-peptide inhibitors of HIV protease from the AIDS virus were developed.

Electronic reproduction.
Amsterdam :
Elsevier Science & Technology,
2007.

Mode of access: World Wide Web.

ISBN: 9780762305933

Source: 126556:127737Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

203135
Pharmaceutical chemistry.
Index Terms--Genre/Form:

214472
Electronic books.

LC Class. No.: RS400 / .A35eb v. 5

Dewey Class. No.: 615/.19

Advances in medicinal chemistry.Volume 5
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