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Histopathology of preclinical toxicity studiesinterpretation and relevance in drug safety evaluation /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Histopathology of preclinical toxicity studiesPeter Greaves.
Reminder of title:	interpretation and relevance in drug safety evaluation /
Author:	Greaves, P.
Published:	Amsterdam ;Academic Press,2007.
Description:	1 online resource (vii, 953 p.) :col. ill.
Subject:	DrugsToxicity testing.
Online resource:	http://www.sciencedirect.com/science/book/9780444527714
ISBN:	9780444527714

Histopathology of preclinical toxicity studiesinterpretation and relevance in drug safety evaluation /
Greaves, P.M.B., Ch.B.

Histopathology of preclinical toxicity studiesinterpretation and relevance in drug safety evaluation /[electronic resource] :Peter Greaves. - 3rd ed. - Amsterdam ;Academic Press,2007. - 1 online resource (vii, 953 p.) :col. ill.

Includes bibliographical references and index.

Introduction -- Integumentary System -- Mammary Gland -- Haemopoietic and Lymphatic Systems -- Musculoskeletal System -- Respiratory Tract -- Cardiovascular System -- Gastrointestinal tract.

This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature of pathological changes in pre-clinical studies and assessment of their relevance to the clinical investigation of new drugs is also covered. Numerous colour photographs are included that highlight and embellish the histopathological features that are described. It also contains many pertinent references to both human and animal pathology forming an essential basis for the assessment of drug-induced pathology. NEW TO THE THIRD EDITION: * Covers drug induced pathology in preclinical (animal) studies and their relevance for patients or volunteers in clinical studies * General comments to each chapter about the relevance of pathological findings to humans * Provides essential information that can help decide the relevance of particular lesions for patients.

ISBN: 9780444527714

Source: 133525:133650Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

571194
Drugs
--Toxicity testing.Index Terms--Genre/Form:

214472
Electronic books.

LC Class. No.: RA1238 / .G74 2007

Dewey Class. No.: 615.9

National Library of Medicine Call No.: 2007 F-019

Histopathology of preclinical toxicity studiesinterpretation and relevance in drug safety evaluation /
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