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The kidneyfrom normal development to congenital diseases /
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
The kidneyedited by Peter D. Vize, Adrian S. Woolf, Jonathan B.L. Bard.
其他題名:
from normal development to congenital diseases /
其他作者:
Vize, Peter D.
出版者:
Amsterdam ;Academic Press,c2003.
面頁冊數:
1 online resource (xiii, 519 p.) :ill. (chiefly col.)
標題:
KidneysGrowth.
電子資源:
http://www.sciencedirect.com/science/book/9780127224411
ISBN:
9780127224411
The kidneyfrom normal development to congenital diseases /
The kidney
from normal development to congenital diseases /[electronic resource] :edited by Peter D. Vize, Adrian S. Woolf, Jonathan B.L. Bard. - Amsterdam ;Academic Press,c2003. - 1 online resource (xiii, 519 p.) :ill. (chiefly col.)
Includes bibliographical references and index.
Foreword -- SECTION 1: EMBRYONIC KIDNEYS AND MODELS -- 1. Introduction: the embryonic kidneys and other nephrogenic models -- 2. Development of the Malpighian tubules in Drosophila melanogaster -- 3. Induction, development and physiology of the pronephric tubules -- 4. Formation of the nephric duct -- 5. The pronephric glomus and vasculature -- 6. Development of the mesonephric kidney -- 7. 3-Dimensional anatomy of mammalian mesonephroi -- 8. The Molecular control of pronephros development- an Overview -- 9. Embryological, genetic and molecular tools for investigating embryonic kidney development -- SECTION 2: THE ADULT KIDNEYS -- 10. Introduction -- 11. Anatomy and Histology of the Human Urinary System -- 12. Development of the Ureteric Bud -- 13. The Fates of the Metanephric Mesenchyme -- 14. The Formation and Development of Nephrons -- 15. Establishment of polarity in epithelial cells of the developing nephron -- 16. Development of the Glomerular Capillary and its Basement Membrane -- 17. The development of kidney blood vessels -- 18. The Development of function in the metanephric kidney -- 19. Experimental methods for studying urogenital development -- 20. Overview: The Molecular Basis of Kidney Development -- SECTION 3: CONGENITAL DISEASE -- 21. Maldevelopment of the Human Kidney and Lower Urinary Tract: an Overview -- 22. Wilms' Tumor and related disorders -- 23. Pax-2 and Renal-Coloboma Syndrome -- 24. Polycystic Kidney Disease, von Hippel Lindau and Tuberous sclerosis -- 26. Renal Cell Carcinoma: The Human Disease -- 27. The Tubule -- 28. Diseases of the Glomerular Filtration Barrier: Alport Syndrome and Congenital Nephrosis (NPHS1) -- 29. Congenital Kidney Diseases: Prospects for New Therapies.
Organogenesis of the kidney has been intensely studied for over a century. In recent years advances in molecular techniques have not only made great inroads into exploring the genetic regulation of this complex process but also began to unravel the molecular basis of many forms of congenital kidney disease. This book is a comprehensive study on these findings and the only book available with such in depth coverage of the kidney. Key Features * Hundreds of color figures depicting key events in all aspects of kidney development * Full coverage of the genetic and cellular basis of kidney development * Analysis of the genetic basis of the major congenital kidney diseases.
ISBN: 9780127224411
Source: 89199:89199Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:
572055
Kidneys
--Growth.Index Terms--Genre/Form:
214472
Electronic books.
LC Class. No.: QP249 / .K522 2003eb
Dewey Class. No.: 616.6/1043
National Library of Medicine Call No.: 2003 E-961
The kidneyfrom normal development to congenital diseases /
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Foreword -- SECTION 1: EMBRYONIC KIDNEYS AND MODELS -- 1. Introduction: the embryonic kidneys and other nephrogenic models -- 2. Development of the Malpighian tubules in Drosophila melanogaster -- 3. Induction, development and physiology of the pronephric tubules -- 4. Formation of the nephric duct -- 5. The pronephric glomus and vasculature -- 6. Development of the mesonephric kidney -- 7. 3-Dimensional anatomy of mammalian mesonephroi -- 8. The Molecular control of pronephros development- an Overview -- 9. Embryological, genetic and molecular tools for investigating embryonic kidney development -- SECTION 2: THE ADULT KIDNEYS -- 10. Introduction -- 11. Anatomy and Histology of the Human Urinary System -- 12. Development of the Ureteric Bud -- 13. The Fates of the Metanephric Mesenchyme -- 14. The Formation and Development of Nephrons -- 15. Establishment of polarity in epithelial cells of the developing nephron -- 16. Development of the Glomerular Capillary and its Basement Membrane -- 17. The development of kidney blood vessels -- 18. The Development of function in the metanephric kidney -- 19. Experimental methods for studying urogenital development -- 20. Overview: The Molecular Basis of Kidney Development -- SECTION 3: CONGENITAL DISEASE -- 21. Maldevelopment of the Human Kidney and Lower Urinary Tract: an Overview -- 22. Wilms' Tumor and related disorders -- 23. Pax-2 and Renal-Coloboma Syndrome -- 24. Polycystic Kidney Disease, von Hippel Lindau and Tuberous sclerosis -- 26. Renal Cell Carcinoma: The Human Disease -- 27. The Tubule -- 28. Diseases of the Glomerular Filtration Barrier: Alport Syndrome and Congenital Nephrosis (NPHS1) -- 29. Congenital Kidney Diseases: Prospects for New Therapies.
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Organogenesis of the kidney has been intensely studied for over a century. In recent years advances in molecular techniques have not only made great inroads into exploring the genetic regulation of this complex process but also began to unravel the molecular basis of many forms of congenital kidney disease. This book is a comprehensive study on these findings and the only book available with such in depth coverage of the kidney. Key Features * Hundreds of color figures depicting key events in all aspects of kidney development * Full coverage of the genetic and cellular basis of kidney development * Analysis of the genetic basis of the major congenital kidney diseases.
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