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Bone marrow transplantation across m...

Martelli, M. F.

Bone marrow transplantation across major genetic barriers

Record Type:	Electronic resources : Monograph/item
Title/Author:	Bone marrow transplantation across major genetic barrierseditors, Yair Reisner, Massimo F. Martelli.
other author:	Reisner, Yair.
Published:	Singapore ;World Scientific Pub. Co.,c2010.
Description:	xi, 479 p. :ill. (some col.)
Subject:	Bone marrowTransplantation.
Online resource:	http://www.worldscientific.com/worldscibooks/10.1142/7248#t=toc
ISBN:	9789814271271 (electronic bk.)

Bone marrow transplantation across major genetic barriers
Bone marrow transplantation across major genetic barriers[electronic resource] /editors, Yair Reisner, Massimo F. Martelli. - Singapore ;World Scientific Pub. Co.,c2010. - xi, 479 p. :ill. (some col.)

Includes bibliographical references and index.

The importance of bone marrow transplantation for patients who do not have a matched sibling donor cannot be overestimated. This subject has always been in the public domain, accentuated by dramatic appeals, from time to time, to search for matched volunteer donors in the public at large. Unfortunately, the availability of such donors is limited, due to the remarkable genetic diversity of humans. Thus, although registries of such volunteers now include more than eight million individuals, we still face the problem of finding a matched donor for about 30% of patients in need. To address this burning issue, extensive clinical and basic research is performed in leading institutes around the world. This book presents updated accounts of the different aspects of this research. The scope of the book is very wide, including strategies to overcome graft vs. host (GVH) disease and graft rejection, cell therapy to prevent leukemia relapse, and a range of modalities to improve immune reconstitution after transplantation. In addition, new approaches to induce immune tolerance towards organ transplants by means of hematopoietic stem cell transplantation are extensively reviewed.

Electronic reproduction.
Singapore :
World Scientific Publishing Co.,
2010.

System requirements: Adobe Acrobat Reader.

ISBN: 9789814271271 (electronic bk.)Subjects--Topical Terms:

575858
Bone marrow
--Transplantation.

LC Class. No.: RD123.5

Dewey Class. No.: 617.4/410592

Bone marrow transplantation across major genetic barriers
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245 0 0 $a Bone marrow transplantation across major genetic barriers $h [electronic resource] / $c editors, Yair Reisner, Massimo F. Martelli.
260 $a Singapore ; $a Hackensack, N.J. : $b World Scientific Pub. Co., $c c2010.
300 $a xi, 479 p. : $b ill. (some col.)
504 $a Includes bibliographical references and index.
520 $a The importance of bone marrow transplantation for patients who do not have a matched sibling donor cannot be overestimated. This subject has always been in the public domain, accentuated by dramatic appeals, from time to time, to search for matched volunteer donors in the public at large. Unfortunately, the availability of such donors is limited, due to the remarkable genetic diversity of humans. Thus, although registries of such volunteers now include more than eight million individuals, we still face the problem of finding a matched donor for about 30% of patients in need. To address this burning issue, extensive clinical and basic research is performed in leading institutes around the world. This book presents updated accounts of the different aspects of this research. The scope of the book is very wide, including strategies to overcome graft vs. host (GVH) disease and graft rejection, cell therapy to prevent leukemia relapse, and a range of modalities to improve immune reconstitution after transplantation. In addition, new approaches to induce immune tolerance towards organ transplants by means of hematopoietic stem cell transplantation are extensively reviewed.
533 $a Electronic reproduction. $b Singapore : $c World Scientific Publishing Co., $d 2010. $n System requirements: Adobe Acrobat Reader. $n Mode of access: World Wide Web. $n Available to subscribing institutions.
650 0 $a Bone marrow $x Transplantation. $3 575858
650 0 $a Hematopoietic stem cells. $3 200255
650 0 $a Graft versus host disease $x Prevention. $3 575859
650 0 $a Graft rejection $x Prevention. $3 575860
650 0 $a Human immunogenetics. $3 563199
700 1 $a Reisner, Yair. $3 575856
700 1 $a Martelli, M. F. $3 575857
710 2 $a World Scientific (Firm) $3 575130
776 1 $z 9814271268 (hbk.)
776 1 $z 9789814271264 (hbk.)
856 4 0 $u http://www.worldscientific.com/worldscibooks/10.1142/7248#t=toc