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Alkaloidschemical and biological per...

Pelletier, S. W. (1924-2004.)

Alkaloidschemical and biological perspectives /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Alkaloidsedited by S. William Pelletier and Departement of Chemistry, the University of Georgia.
Reminder of title:	chemical and biological perspectives /
other author:	Pelletier, S. W.
Published:	Amsterdam :Elsevier ;1998-<>
Description:	1 online resource (v. <1-12>) :ill.
Subject:	Alkaloids.
Online resource:	http://www.sciencedirect.com/science/book/9780080428055
ISBN:	9780080428055

Alkaloidschemical and biological perspectives /
Alkaloidschemical and biological perspectives /[electronic resource] :edited by S. William Pelletier and Departement of Chemistry, the University of Georgia. - 1st ed. - Amsterdam :Elsevier ;1998-<> - 1 online resource (v. <1-12>) :ill.

Includes bibliographical references and indexes.

Acronycine-type alkaloids: chemistry and biology (F. Tillequin <IT>et al</IT>.). <IT>Solanum</IT> steroid alkaloids -- an update (H. Ripperger). Synthesis and structure-activity studies of <IT>Lissoclinum</IT> peptide alkaloids (P. Wipf). Pyroglutamate as a chiral template for the synthesis of alkaloids (M.B. Smith). Analysis of alkaloids by capillary electrophoresis and capillary electrophoresis -- electrospray mass spectrometry (J. S�tckigt <IT>et al</IT>.). Oxidation of anthelmentic marcofortine A, an indole alkaloid (B.H. Lee <IT>et al</IT>.). Subject index. Organism index.

Acronycine, a potent antitumor agent, was discovered in the bark of the small Australian Rutaceous tree, <IT>Acronychia baueri </IT>Schott. This new work presents a comprehensive survey of the isolation, structure determination, methods of synthesis, and the biological properties of acronycine, as well as an account of natural and synthetic analogues of acronycine, and their biological properties. Solanum alkaloids were reviewed in 1990 and this book surveys the new developments (isolation procedures, structural elucidation methods) and critically updates earlier reviews. In addition it presents the interesting chemistry and synthesis of cyclopeptide alkaloids. These cyclopeptide alkaloids have been isolated from ascidians, sea hares, and cyanobacteria. Also included are reviews of the use of the functionalized lactam, pyroglutamic acid, as a chiral template for the synthesis of alkaloids. The second review examines the on-line coupling of capillary electrophoresis (CE) and mass spectrometry (MS) for the analysis of alkaloid mixtures. Finally a review of oxygenated analogs of the alkaloid Marcfortine for their potent antiparasitic activity is included at the end of this work. Each chapter in this volume has been reviewed by at least one expert in the field. Indexes for both subjects and organisms are provided.

ISBN: 9780080428055

Source: 120829:127132Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

201438
Alkaloids.
Index Terms--Genre/Form:

214472
Electronic books.

LC Class. No.: QD421 / .A45 1998

Dewey Class. No.: 547/.7

Alkaloidschemical and biological perspectives /
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260 $a Amsterdam : $b Elsevier ; $a [Oxford] : $b Pergamon, $c 1998-<>
300 $a 1 online resource (v. <1-12>) : $b ill.
504 $a Includes bibliographical references and indexes.
505 0 $a Acronycine-type alkaloids: chemistry and biology (F. Tillequin <IT>et al</IT>.). <IT>Solanum</IT> steroid alkaloids -- an update (H. Ripperger). Synthesis and structure-activity studies of <IT>Lissoclinum</IT> peptide alkaloids (P. Wipf). Pyroglutamate as a chiral template for the synthesis of alkaloids (M.B. Smith). Analysis of alkaloids by capillary electrophoresis and capillary electrophoresis -- electrospray mass spectrometry (J. S�tckigt <IT>et al</IT>.). Oxidation of anthelmentic marcofortine A, an indole alkaloid (B.H. Lee <IT>et al</IT>.). Subject index. Organism index.
520 $a Acronycine, a potent antitumor agent, was discovered in the bark of the small Australian Rutaceous tree, <IT>Acronychia baueri </IT>Schott. This new work presents a comprehensive survey of the isolation, structure determination, methods of synthesis, and the biological properties of acronycine, as well as an account of natural and synthetic analogues of acronycine, and their biological properties. Solanum alkaloids were reviewed in 1990 and this book surveys the new developments (isolation procedures, structural elucidation methods) and critically updates earlier reviews. In addition it presents the interesting chemistry and synthesis of cyclopeptide alkaloids. These cyclopeptide alkaloids have been isolated from ascidians, sea hares, and cyanobacteria. Also included are reviews of the use of the functionalized lactam, pyroglutamic acid, as a chiral template for the synthesis of alkaloids. The second review examines the on-line coupling of capillary electrophoresis (CE) and mass spectrometry (MS) for the analysis of alkaloid mixtures. Finally a review of oxygenated analogs of the alkaloid Marcfortine for their potent antiparasitic activity is included at the end of this work. Each chapter in this volume has been reviewed by at least one expert in the field. Indexes for both subjects and organisms are provided.
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