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Fluorine in pharmaceutical and medic...

Gouverneur, Véronique.

Fluorine in pharmaceutical and medicinal chemistryfrom biophysical aspects to clinial applications /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Fluorine in pharmaceutical and medicinal chemistryVéronique Gouverneur, Klaus Müller, editors.
Reminder of title:	from biophysical aspects to clinial applications /
other author:	Gouverneur, Véronique.
Published:	London :Imperial College Press ;2012.
Description:	1 online resource (xxiii, 546 p.) :ill. (some col.)
Subject:	Fluorine.
Online resource:	http://www.worldscientific.com/worldscibooks/10.1142/P746#t=toc
ISBN:	9781848166363 (electronic bk.)

Fluorine in pharmaceutical and medicinal chemistryfrom biophysical aspects to clinial applications /
Fluorine in pharmaceutical and medicinal chemistryfrom biophysical aspects to clinial applications /[electronic resource] :Véronique Gouverneur, Klaus Müller, editors. - London :Imperial College Press ;2012. - 1 online resource (xxiii, 546 p.) :ill. (some col.) - Molecular medicine and medicinal chemistry ;6. - Molecular medicine and medicinal chemistry ;v. 1..

Includes bibliographical references and index.

Fluorine chemistry is an expanding area of research that is attracting international interest, due to the impact of fluorine in drug discovery and in clinical and molecular imaging (e.g. PET, MRI). Many researchers and academics are entering this area of research, while scientists in industrial and clinical environments are also indirectly exposed to fluorine chemistry through the use of fluorinated compounds for imaging. This book provides an overview of the impact that fluorine has made in the life sciences. In the first section, the emphasis is on how fluorine substitution of amino acids, peptides, nucleobases and carbohydrates can provide invaluable information at a molecular level. The following chapters provide answers to the key questions posed on the importance of fluorine in drug discovery and clinical applications. For example, the reader will discover how fluorine has found its place as a key element in improving drug efficacy, with reference to some of the best-selling drugs on the market. Finally, a thorough review on the design, synthesis and use of 18F-radiotracers for positron emission tomography is provided, and this is complemented with a discussion on how 19F NMR has advanced molecular and clinical imaging.

ISBN: 9781848166363 (electronic bk.)

Standard No.: 9786613645890Subjects--Topical Terms:

208579
Fluorine.
Index Terms--Genre/Form:

214472
Electronic books.

LC Class. No.: RS400 / .F58 2012eb

Dewey Class. No.: 615.19

National Library of Medicine Call No.: QV 185 / F58 2012

Fluorine in pharmaceutical and medicinal chemistryfrom biophysical aspects to clinial applications /
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300 $a 1 online resource (xxiii, 546 p.) : $b ill. (some col.)
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504 $a Includes bibliographical references and index.
520 $a Fluorine chemistry is an expanding area of research that is attracting international interest, due to the impact of fluorine in drug discovery and in clinical and molecular imaging (e.g. PET, MRI). Many researchers and academics are entering this area of research, while scientists in industrial and clinical environments are also indirectly exposed to fluorine chemistry through the use of fluorinated compounds for imaging. This book provides an overview of the impact that fluorine has made in the life sciences. In the first section, the emphasis is on how fluorine substitution of amino acids, peptides, nucleobases and carbohydrates can provide invaluable information at a molecular level. The following chapters provide answers to the key questions posed on the importance of fluorine in drug discovery and clinical applications. For example, the reader will discover how fluorine has found its place as a key element in improving drug efficacy, with reference to some of the best-selling drugs on the market. Finally, a thorough review on the design, synthesis and use of 18F-radiotracers for positron emission tomography is provided, and this is complemented with a discussion on how 19F NMR has advanced molecular and clinical imaging.
588 $a Description based on print version record.
650 0 $a Fluorine. $3 208579
650 0 $a Pharmaceutical chemistry. $3 203135
655 0 $a Electronic books. $2 local. $3 214472
700 1 $a Gouverneur, Véronique. $3 648050
700 1 $a Müller, Klaus. $3 648051
830 0 $a Molecular medicine and medicinal chemistry ; $v v. 1. $3 575724
856 4 0 $u http://www.worldscientific.com/worldscibooks/10.1142/P746#t=toc