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Adaptive and flexible clinical trials

Chin, Richard.

Adaptive and flexible clinical trials

Record Type:	Electronic resources : Monograph/item
Title/Author:	Adaptive and flexible clinical trialsRichard Chin.
Author:	Chin, Richard.
Published:	Boca Raton, Fla. :CRC Press,2011.
Description:	1 online resource (xiii, 184 p.) :ill.
Notes:	"A Chapman & Hall book."
Subject:	Clinical trials.
Online resource:	http://www.crcnetbase.com/doi/book/10.1201/b11099
ISBN:	9781439838334 (electronic bk.)

Adaptive and flexible clinical trials
Chin, Richard.

Adaptive and flexible clinical trials[electronic resource] /Richard Chin. - Boca Raton, Fla. :CRC Press,2011. - 1 online resource (xiii, 184 p.) :ill.

"A Chapman & Hall book."

Includes bibliographical references and index.

1. Background -- 2. Conventional statistics -- 3. Statistics used in adaptive clinical trials -- 4. Specific requirements for adaptive trials -- 5. Adaptive randomization and allocation -- 6. Sample size reestimation -- 7. Traditional dosing -- 8. Adaptive dosing -- 9. Interim analysis and adaptive termination of study and study arms -- 10. Adaptive changes in study design and decision rules -- 11. Seamless designs and adaptive clinical trial conduct -- 12. Analysis and interpretation of results.

ISBN: 9781439838334 (electronic bk.)Subjects--Topical Terms:

181901
Clinical trials.

LC Class. No.: R853.C55 / C45 2011

Dewey Class. No.: 615.50724 / C539

Adaptive and flexible clinical trials
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020 $a 9781439838334 (electronic bk.)
020 $a 143983833X (electronic bk.)
020 $z 9781439838327
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040 $a OTZ $b eng $e pn $c OTZ $d CUS $d GZM $d N $d YDXCP $d OCLCQ $d OHS $d DEBSZ $d UIU $d OCLCF $d CRCPR $d OCLCQ $d OCLCO
050 4 $a R853.C55 $b C45 2011
082 4 $a 615.50724 $b C539
100 1 $a Chin, Richard. $3 571009
245 1 0 $a Adaptive and flexible clinical trials $h [electronic resource] / $c Richard Chin.
260 $a Boca Raton, Fla. : $b CRC Press, $c 2011.
300 $a 1 online resource (xiii, 184 p.) : $b ill.
500 $a "A Chapman & Hall book."
504 $a Includes bibliographical references and index.
505 0 $a 1. Background -- 2. Conventional statistics -- 3. Statistics used in adaptive clinical trials -- 4. Specific requirements for adaptive trials -- 5. Adaptive randomization and allocation -- 6. Sample size reestimation -- 7. Traditional dosing -- 8. Adaptive dosing -- 9. Interim analysis and adaptive termination of study and study arms -- 10. Adaptive changes in study design and decision rules -- 11. Seamless designs and adaptive clinical trial conduct -- 12. Analysis and interpretation of results.
650 0 $a Clinical trials. $3 181901
856 4 0 $u http://www.crcnetbase.com/doi/book/10.1201/b11099