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IgE antibodiesgeneration and function /

Curotto de Lafaille, Maria A.

IgE antibodiesgeneration and function /

Record Type:	Electronic resources : Monograph/item
Title/Author:	IgE antibodiesedited by Juan J. Lafaille, Maria A. Curotto de Lafaille.
Reminder of title:	generation and function /
other author:	Lafaille, Juan J.
Published:	Cham :Springer International Publishing :2015.
Description:	ix, 152 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Immunoglobulin E.
Online resource:	http://dx.doi.org/10.1007/978-3-319-13725-4
ISBN:	9783319137254 (electronic bk.)

IgE antibodiesgeneration and function /
IgE antibodiesgeneration and function /[electronic resource] :edited by Juan J. Lafaille, Maria A. Curotto de Lafaille. - Cham :Springer International Publishing :2015. - ix, 152 p. :ill. (some col.), digital ;24 cm. - Current topics in microbiology and immunology,v.3880070-217X ;. - Current topics in microbiology and immunology ;v.351..

Biology of IgE Production: IgE Cell Differentiation and the Memory of IgE Responses -- Molecular Mechanisms of IgE Class Switch Recombination -- Anti-IgE Therapy: Clinical Utility and Mechanistic Insights -- New Insights on the Signaling and Function of the High Affinity Receptor for IgE -- Helminth-Induced IgE and Protection Against Allergic Disorders -- IgE Immunotherapy Against Cancer.

This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and cellular level. Furthermore, it discusses in detail novel findings on how the affinity, specificity and cross-reactivity of IgE can fine-tune mast cell responses to allergens. The book also explores the beneficial roles of IgE antibodies in immunity to helminthes and protection against tumors, and how the properties of IgE-mediated immunity are employed in the development of IgE therapeutic antibodies. All chapters were written by respected experts in their fields and will appeal to scientists and clinicians alike.

ISBN: 9783319137254 (electronic bk.)

Standard No.: 10.1007/978-3-319-13725-4doiSubjects--Topical Terms:

484441
Immunoglobulin E.

LC Class. No.: QR186.8.E2

Dewey Class. No.: 571.967

IgE antibodiesgeneration and function /
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300 $a ix, 152 p. : $b ill. (some col.), digital ; $c 24 cm.
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505 0 $a Biology of IgE Production: IgE Cell Differentiation and the Memory of IgE Responses -- Molecular Mechanisms of IgE Class Switch Recombination -- Anti-IgE Therapy: Clinical Utility and Mechanistic Insights -- New Insights on the Signaling and Function of the High Affinity Receptor for IgE -- Helminth-Induced IgE and Protection Against Allergic Disorders -- IgE Immunotherapy Against Cancer.
520 $a This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and cellular level. Furthermore, it discusses in detail novel findings on how the affinity, specificity and cross-reactivity of IgE can fine-tune mast cell responses to allergens. The book also explores the beneficial roles of IgE antibodies in immunity to helminthes and protection against tumors, and how the properties of IgE-mediated immunity are employed in the development of IgE therapeutic antibodies. All chapters were written by respected experts in their fields and will appeal to scientists and clinicians alike.
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