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Sugar chainsdecoding the functions o...

Ohtsubo, Kazuaki.

Sugar chainsdecoding the functions of glycans /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Sugar chainsedited by Tadashi Suzuki, Kazuaki Ohtsubo, Naoyuki Taniguchi.
Reminder of title:	decoding the functions of glycans /
other author:	Suzuki, Tadashi.
Published:	Tokyo :Springer Japan :2015.
Description:	viii, 288 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Glycomics.
Online resource:	http://dx.doi.org/10.1007/978-4-431-55381-6
ISBN:	9784431553816 (electronic bk.)

Sugar chainsdecoding the functions of glycans /
Sugar chainsdecoding the functions of glycans /[electronic resource] :edited by Tadashi Suzuki, Kazuaki Ohtsubo, Naoyuki Taniguchi. - Tokyo :Springer Japan :2015. - viii, 288 p. :ill., digital ;24 cm.

1 N-Glycans and Quality Control of Proteins -- 2 Glycan-Mediated Protein Transport from the Endoplasmic Reticulum -- 3 Gangliosides and T-Cell Immunity -- 4 Gangliosides Regulate Tumor Properties: With Focus on the Suppression of Metastasis-Associated ppGalNAc-T13 with GM1 -- 5 Role of Glycans in Viral Infection -- 6 Discovery and Applications of a Novel Human Pluripotent Stem Cell-Specific Lectin Probe rBC2LCN -- 7 Glycan Structure and Neural Plasticity -- 8 The Involvement of Midkine, a Heparin-Binding Growth Factor, in Cancer Development -- 9 Tumor-Associated Glycans and Their Functional Roles in the Multistep Process of Human Cancer Progression -- 10 Mammalian Sialidase and Tumor Development -- 11 Roles of Glycans in Immune Evasion from NK Immunity -- 12 Glycomic Analysis of Cancer -- 13 Glyco-Predisposing Factor of Diabetes -- 14 Macrophages Govern Ganglioside GM3 Expression in Adipocytes to Regulate Adipogenesis and Insulin Signaling in Homeostatic and Pathogenic Conditions -- 15 O-Mannosyl Glycan and Muscular Dystrophy -- 16 Glycans and Chronic Obstructive Pulmonary Disease (COPD) -- 17 [alpha]1,6-Fucosyltransferase Knockout Mice and Schizophrenia-Like Phenotype.

This book presents the latest breakthrough results in glycobiology regarding the roles of glycans in relation to quality control and transport of protein, the immune system, viral infection, stem cells, the neural system, and various diseases such as cancer, diabetes, chronic obstructive pulmonary disease, muscular dystrophy, and schizophrenia. Although glycoscience has long been regarded as a very specialized field with no simple analytical method, the recent explosive progress in research continues to provide limitless evidence that glycan chains are the key component in various biological phenomena. Cell surface glycans, for example, change with developmental stages or environmental conditions and thus represent a "face" of the cell that is utilized for identification of iPS and ES cells and as biomarkers in diagnosis or detection of cancer. This book comprises 17 chapters, each of which poses outstanding "glyco-related" questions enabling non-specialists to have a clearer idea about what the future direction for further investigation of glycans in their own research fields will be. Also including basic information to understand the nature of glycans, this title serves as an excellent "textbook" for researchers in diverse research fields who are not familiar with, but nevertheless interested in, glycan chains or sugar chains.

ISBN: 9784431553816 (electronic bk.)

Standard No.: 10.1007/978-4-431-55381-6doiSubjects--Topical Terms:

372539
Glycomics.

LC Class. No.: QP702.G577

Dewey Class. No.: 572.567

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245 1 0 $a Sugar chains $h [electronic resource] : $b decoding the functions of glycans / $c edited by Tadashi Suzuki, Kazuaki Ohtsubo, Naoyuki Taniguchi.
260 $a Tokyo : $b Springer Japan : $b Imprint: Springer, $c 2015.
300 $a viii, 288 p. : $b ill., digital ; $c 24 cm.
505 0 $a 1 N-Glycans and Quality Control of Proteins -- 2 Glycan-Mediated Protein Transport from the Endoplasmic Reticulum -- 3 Gangliosides and T-Cell Immunity -- 4 Gangliosides Regulate Tumor Properties: With Focus on the Suppression of Metastasis-Associated ppGalNAc-T13 with GM1 -- 5 Role of Glycans in Viral Infection -- 6 Discovery and Applications of a Novel Human Pluripotent Stem Cell-Specific Lectin Probe rBC2LCN -- 7 Glycan Structure and Neural Plasticity -- 8 The Involvement of Midkine, a Heparin-Binding Growth Factor, in Cancer Development -- 9 Tumor-Associated Glycans and Their Functional Roles in the Multistep Process of Human Cancer Progression -- 10 Mammalian Sialidase and Tumor Development -- 11 Roles of Glycans in Immune Evasion from NK Immunity -- 12 Glycomic Analysis of Cancer -- 13 Glyco-Predisposing Factor of Diabetes -- 14 Macrophages Govern Ganglioside GM3 Expression in Adipocytes to Regulate Adipogenesis and Insulin Signaling in Homeostatic and Pathogenic Conditions -- 15 O-Mannosyl Glycan and Muscular Dystrophy -- 16 Glycans and Chronic Obstructive Pulmonary Disease (COPD) -- 17 [alpha]1,6-Fucosyltransferase Knockout Mice and Schizophrenia-Like Phenotype.
520 $a This book presents the latest breakthrough results in glycobiology regarding the roles of glycans in relation to quality control and transport of protein, the immune system, viral infection, stem cells, the neural system, and various diseases such as cancer, diabetes, chronic obstructive pulmonary disease, muscular dystrophy, and schizophrenia. Although glycoscience has long been regarded as a very specialized field with no simple analytical method, the recent explosive progress in research continues to provide limitless evidence that glycan chains are the key component in various biological phenomena. Cell surface glycans, for example, change with developmental stages or environmental conditions and thus represent a "face" of the cell that is utilized for identification of iPS and ES cells and as biomarkers in diagnosis or detection of cancer. This book comprises 17 chapters, each of which poses outstanding "glyco-related" questions enabling non-specialists to have a clearer idea about what the future direction for further investigation of glycans in their own research fields will be. Also including basic information to understand the nature of glycans, this title serves as an excellent "textbook" for researchers in diverse research fields who are not familiar with, but nevertheless interested in, glycan chains or sugar chains.
650 0 $a Glycomics. $3 372539
650 1 4 $a Life Sciences. $3 273679
650 2 4 $a Biochemistry, general. $3 273649
650 2 4 $a Cancer Research. $3 273660
650 2 4 $a Immunology. $3 189152
700 1 $a Suzuki, Tadashi. $3 713918
700 1 $a Ohtsubo, Kazuaki. $3 713919
700 1 $a Taniguchi, Naoyuki. $3 225531
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-4-431-55381-6
950 $a Biomedical and Life Sciences (Springer-11642)