國立高雄大學圖資館 |

Language: English

Back

Longevity genesa blueprint for aging /

Atzmon, Gil.

Longevity genesa blueprint for aging /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Longevity genesedited by Gil Atzmon, PhD.
Reminder of title:	a blueprint for aging /
other author:	Atzmon, Gil.
Published:	New York, NY :Springer New York :2015.
Description:	xi, 194 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	LongevityGenetic aspects.
Online resource:	http://dx.doi.org/10.1007/978-1-4939-2404-2
ISBN:	9781493924042 (electronic bk.)

Longevity genesa blueprint for aging /
Longevity genesa blueprint for aging /[electronic resource] :edited by Gil Atzmon, PhD. - New York, NY :Springer New York :2015. - xi, 194 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v.8470065-2598 ;. - Advances in experimental medicine and biology ;946..

Evolutionary Genetic Bases of Longevity and Senescence -- Candidate Genes That Affect Aging Through Protein Homeostasis -- Autophagy and Aging -- A Genetic View of the Mitochondrial Role in Aging: Killing Us Softly -- GWAS and Meta-analysis in Aging/Longevity -- Exome and Whole Genome Sequencing in Aging and Longevity -- Models to Explore Genetics of Human Aging -- Systems Biology of Aging -- Epigenetics of Aging.

The release of the complete version of the human genome sequence in 2003 has paved the way for defining gene function and genetic background for phenotypic variation in humans and allowed us to study the aging process in a new light. This new volume results from that research and focuses on the genetic and epigenetic process of aging. While the interpretation of the genome data is still in its initial stages, this new volume looks at the evolving understanding of molecular mechanisms involved in cellular processes, gene function associated with complex traits, epigenetic components involve in gene control and the creation of hypothesis-free genome-wide approaches. Longevity Genes: A Blueprint for Aging explores the genetic and genomic elements that can maintain a long life such as DNA damage mechanisms, epigenetics and the way we can use this knowledge to generate customized treatments. It touches on some of the multidisciplinary approaches as well as genomic-wide association technology used to analyze complex traits. This book describes the hunt for genes affecting complex traits using a high throughput technology, with adequate consideration for the selection of an appropriate population, applications of statistical genetics and computational biology, and most importantly, considering phenotype-genotype association studies. Longevity Genes provides coverage of not only established aspects of genetics and aging, but also new approaches and perceptions in this important area of research.

ISBN: 9781493924042 (electronic bk.)

Standard No.: 10.1007/978-1-4939-2404-2doiSubjects--Topical Terms:

719062
Longevity
--Genetic aspects.

LC Class. No.: QP85

Dewey Class. No.: 612.68

Longevity genesa blueprint for aging /
LDR:02947nmm a2200325 a 4500 001 465382
003 DE-He213
005 20151104111804.0
006 m d
007 cr nn 008maaau
008 151222s2015 nyu s 0 eng d
020 $a 9781493924042 (electronic bk.)
020 $a 9781493924035 (paper)
024 7 $a 10.1007/978-1-4939-2404-2 $2 doi
035 $a 978-1-4939-2404-2
040 $a GP $c GP
041 0 $a eng
050 4 $a QP85
072 7 $a MFN $2 bicssc
072 7 $a MED107000 $2 bisacsh
082 0 4 $a 612.68 $2 23
090 $a QP85 $b .L852 2015
245 0 0 $a Longevity genes $h [electronic resource] : $b a blueprint for aging / $c edited by Gil Atzmon, PhD.
260 $a New York, NY : $b Springer New York : $b Imprint: Springer, $c 2015.
300 $a xi, 194 p. : $b ill., digital ; $c 24 cm.
490 1 $a Advances in experimental medicine and biology, $x 0065-2598 ; $v v.847
505 0 $a Evolutionary Genetic Bases of Longevity and Senescence -- Candidate Genes That Affect Aging Through Protein Homeostasis -- Autophagy and Aging -- A Genetic View of the Mitochondrial Role in Aging: Killing Us Softly -- GWAS and Meta-analysis in Aging/Longevity -- Exome and Whole Genome Sequencing in Aging and Longevity -- Models to Explore Genetics of Human Aging -- Systems Biology of Aging -- Epigenetics of Aging.
520 $a The release of the complete version of the human genome sequence in 2003 has paved the way for defining gene function and genetic background for phenotypic variation in humans and allowed us to study the aging process in a new light. This new volume results from that research and focuses on the genetic and epigenetic process of aging. While the interpretation of the genome data is still in its initial stages, this new volume looks at the evolving understanding of molecular mechanisms involved in cellular processes, gene function associated with complex traits, epigenetic components involve in gene control and the creation of hypothesis-free genome-wide approaches. Longevity Genes: A Blueprint for Aging explores the genetic and genomic elements that can maintain a long life such as DNA damage mechanisms, epigenetics and the way we can use this knowledge to generate customized treatments. It touches on some of the multidisciplinary approaches as well as genomic-wide association technology used to analyze complex traits. This book describes the hunt for genes affecting complex traits using a high throughput technology, with adequate consideration for the selection of an appropriate population, applications of statistical genetics and computational biology, and most importantly, considering phenotype-genotype association studies. Longevity Genes provides coverage of not only established aspects of genetics and aging, but also new approaches and perceptions in this important area of research.
650 0 $a Longevity $x Genetic aspects. $3 719062
650 0 $a Aging. $3 188869
650 1 4 $a Biomedicine. $3 273648
650 2 4 $a Human Genetics. $3 273658
650 2 4 $a Bioinformatics. $3 194415
650 2 4 $a Systems Biology. $3 245824
700 1 $a Atzmon, Gil. $3 719061
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
830 0 $a Advances in experimental medicine and biology ; $v 946. $3 557559
856 4 0 $u http://dx.doi.org/10.1007/978-1-4939-2404-2
950 $a Biomedical and Life Sciences (Springer-11642)