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Stem cell biology in neoplasms of th...

Ehtesham, Moneeb.

Stem cell biology in neoplasms of the central nervous system

Record Type:	Electronic resources : Monograph/item
Title/Author:	Stem cell biology in neoplasms of the central nervous systemedited by Moneeb Ehtesham.
other author:	Ehtesham, Moneeb.
Published:	Cham :Springer International Publishing :2015.
Description:	xiii, 190 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Stem cells.
Online resource:	http://dx.doi.org/10.1007/978-3-319-16537-0
ISBN:	9783319165370 (electronic bk.)

Stem cell biology in neoplasms of the central nervous system
Stem cell biology in neoplasms of the central nervous system[electronic resource] /edited by Moneeb Ehtesham. - Cham :Springer International Publishing :2015. - xiii, 190 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v.8530065-2598 ;. - Advances in experimental medicine and biology ;946..

Regulation of Subventricular Zone-Derived Cells Migration in the Adult Brain -- The SVC and Its Relationship to Stem Cell Based Neuro-oncogenesis. - Isolation and characterization of stem cells for human central nervous system malignancies. - The role of stem cells in pediatric central nervous system malignancies. - Laboratory models for central nervous system tumor stem cell research. - Radiation Therapy for Glioma Stem Cells -- Chemoresistance and chemotherapy targeting stem-like cells in malignant glioma -- Immunobiology and Immunotherapeutic targeting of glioma stem cells -- Emerging strategies for the treatment of tumor stem cells in central nervous system malignancies.

This volume presents the most current reviews on how cancer stem cells (CSCs) hypothesis dictates that the continued proliferation of a tumor is dependent on a sub-population of self-renewing and asymmetrically dividing neoplastic stem cells that supply a largely differentiated tumor. This volume provides a comprehensive overview of the characteristics of CSCs, their role in central nervous system (CNS) tumors, and the recent CSC-specific treatment modalities being used. The emerging focus on CSCs in brain tumors represents a paradigm shift in our understanding of the pathogenesis of these neoplasms. Importantly, the realization that a distinct sub-population of cells contributes disproportionately to the growth and sustenance of central nervous system tumors has important implications for the treatment of such tumors. To treat CNS tumors, there is now a growing need to treat CSCs to achieve adequate tumor control.

ISBN: 9783319165370 (electronic bk.)

Standard No.: 10.1007/978-3-319-16537-0doiSubjects--Topical Terms:

200260
Stem cells.

LC Class. No.: QH588.S83

Dewey Class. No.: 616.02774

Stem cell biology in neoplasms of the central nervous system
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520 $a This volume presents the most current reviews on how cancer stem cells (CSCs) hypothesis dictates that the continued proliferation of a tumor is dependent on a sub-population of self-renewing and asymmetrically dividing neoplastic stem cells that supply a largely differentiated tumor. This volume provides a comprehensive overview of the characteristics of CSCs, their role in central nervous system (CNS) tumors, and the recent CSC-specific treatment modalities being used. The emerging focus on CSCs in brain tumors represents a paradigm shift in our understanding of the pathogenesis of these neoplasms. Importantly, the realization that a distinct sub-population of cells contributes disproportionately to the growth and sustenance of central nervous system tumors has important implications for the treatment of such tumors. To treat CNS tumors, there is now a growing need to treat CSCs to achieve adequate tumor control.
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