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Natural compounds as therapeutic agents for amyloidogenic diseases

Record Type:	Electronic resources : Monograph/item
Title/Author:	Natural compounds as therapeutic agents for amyloidogenic diseasesedited by Neville Vassallo.
other author:	Vassallo, Neville.
Published:	Cham :Springer International Publishing :2015.
Description:	vii, 163 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	AmyloidosisChemotherapy.
Online resource:	http://dx.doi.org/10.1007/978-3-319-18365-7
ISBN:	9783319183657 (electronic bk.)

Natural compounds as therapeutic agents for amyloidogenic diseases
Natural compounds as therapeutic agents for amyloidogenic diseases[electronic resource] /edited by Neville Vassallo. - Cham :Springer International Publishing :2015. - vii, 163 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v.8630065-2598 ;. - Advances in experimental medicine and biology ;946..

Olive Oil Phenols as Promising Multi-targeting Agents against Alzheimer's disease -- Alzheimer's disease, Drosophila melanogaster and Polyphenols -- Biflavonoids as Potential Small Molecule Therapeutics for Alzheimer's disease -- Natural Phenolic Compounds as Therapeutic and Preventive Agents for Cerebral Amyloidosis -- Brain Food for Alzheimer-free Ageing: Focus on Herbal Medicines -- Tea Polyphenols in Parkinson's disease -- The Effect of (-)-Epigallo-catechin-(3)-gallate on Amyloidogenic Proteins Suggests a Common Mechanism.

This edited volume concerns a group of devastating neurological disorders that share a common pathological mechanism, namely the aggregation and deposition of insoluble, proteinaceous lesions, termed 'amyloid'. Examples of cerebral amyloid disorders include common neurodegenerative diseases like Alzheimer's disease-related dementia and Parkinson's disease, as well as other less prevalent conditions like Huntington's disease, cerebral amyloid angiopathy and the transmissible prion disorders. A disease-modifying therapeutic agent is still lacking for all these diseases, and there are no approved therapies that target amyloid formation directly. Nevertheless, a large and complex group of natural aromatic compounds known as polyphenols are rapidly emerging as potentially potent anti-amyloidogenic agents. This book collectively presents a considerable body of experimental and epidemiological evidence from peer-reviewed scientific publications that support a role for natural compounds and herbal extracts in the chemoprevention and therapy of amyloidogenic disorders. Each contribution is written by scientific experts in the relevant field; chapters are devoted to Mediterranean diet and olive oil phenols, traditional Chinese medicine, herbal extracts, polyphenols (with a particular emphasis on epigallocatechin-3-gallate) and bi-flavonoids, amongst others. The topic of this book is relevant to a wide audience, from academia and university students in the biological and chemical sciences, to physicians and allied health professionals, as well as people working in the nutraceutical industry.

ISBN: 9783319183657 (electronic bk.)

Standard No.: 10.1007/978-3-319-18365-7doiSubjects--Topical Terms:

726240
Amyloidosis
--Chemotherapy.

LC Class. No.: RC632.A5

Dewey Class. No.: 572.6

Natural compounds as therapeutic agents for amyloidogenic diseases
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520 $a This edited volume concerns a group of devastating neurological disorders that share a common pathological mechanism, namely the aggregation and deposition of insoluble, proteinaceous lesions, termed 'amyloid'. Examples of cerebral amyloid disorders include common neurodegenerative diseases like Alzheimer's disease-related dementia and Parkinson's disease, as well as other less prevalent conditions like Huntington's disease, cerebral amyloid angiopathy and the transmissible prion disorders. A disease-modifying therapeutic agent is still lacking for all these diseases, and there are no approved therapies that target amyloid formation directly. Nevertheless, a large and complex group of natural aromatic compounds known as polyphenols are rapidly emerging as potentially potent anti-amyloidogenic agents. This book collectively presents a considerable body of experimental and epidemiological evidence from peer-reviewed scientific publications that support a role for natural compounds and herbal extracts in the chemoprevention and therapy of amyloidogenic disorders. Each contribution is written by scientific experts in the relevant field; chapters are devoted to Mediterranean diet and olive oil phenols, traditional Chinese medicine, herbal extracts, polyphenols (with a particular emphasis on epigallocatechin-3-gallate) and bi-flavonoids, amongst others. The topic of this book is relevant to a wide audience, from academia and university students in the biological and chemical sciences, to physicians and allied health professionals, as well as people working in the nutraceutical industry.
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