國立高雄大學圖資館 |

Language: English

Back

Pan-cancer integrative molecular por...

Kamal, Maud.

Pan-cancer integrative molecular portrait towards a new paradigm in precision medicine

Record Type:	Electronic resources : Monograph/item
Title/Author:	Pan-cancer integrative molecular portrait towards a new paradigm in precision medicineedited by Christophe Le Tourneau, Maud Kamal.
other author:	Le Tourneau, Christophe.
Published:	Cham :Springer International Publishing :2015.
Description:	x, 144 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Clinical trials.
Online resource:	http://dx.doi.org/10.1007/978-3-319-22189-2
ISBN:	9783319221892$q(electronic bk.)

Pan-cancer integrative molecular portrait towards a new paradigm in precision medicine
Pan-cancer integrative molecular portrait towards a new paradigm in precision medicine[electronic resource] /edited by Christophe Le Tourneau, Maud Kamal. - Cham :Springer International Publishing :2015. - x, 144 p. :ill. (some col.), digital ;24 cm.

Introduction: Rationale for Precision Medicine Clinical Trials -- The Key Role of Pathology in the Context of Precision Medicine Trials -- Basis for Molecular Genetics in Cancer -- Microarrays Based Molecular Profiling to Identify Genomic Alterations -- High Throughput Technologies: DNA and RNA Sequencing Strategies and Potential -- Bioinformatics for Precision Medicine in Oncology -- Assessment of Biomarkers' Predictive Value of Efficacy -- Designs for Evaluating Precision Medicine Trials -- Conclusions and Perspectives: Challenges for the Clinical Implementation of Precision Medicine Trials.

This original book provides readers with an overview of the latest developments in personalized medicine clinical trials in oncology. The topics covered range from the rationale behind this new generation of clinical trials and the latest statistical models for high-throughput molecular techniques, bioinformatics, high-throughput screening molecular techniques and the challenges entailed by implementing them in daily practice. It also covers the key role of pathology in the validation of molecular results and the complex assessment of predictive biomarkers. The different topics covered are supplemented by unique concrete examples based on the SHIVA trial. The authors are all members of the French Curie Institute, one of the world's foremost cancer research institutions.

ISBN: 9783319221892$q(electronic bk.)

Standard No.: 10.1007/978-3-319-22189-2doiSubjects--Topical Terms:

181901
Clinical trials.

LC Class. No.: R853.C55

Dewey Class. No.: 616.027

Pan-cancer integrative molecular portrait towards a new paradigm in precision medicine
LDR:02369nmm a2200313 a 4500 001 475178
003 DE-He213
005 20160308102132.0
006 m d
007 cr nn 008maaau
008 160420s2015 gw s 0 eng d
020 $a 9783319221892$q(electronic bk.)
020 $a 9783319221885$q(paper)
024 7 $a 10.1007/978-3-319-22189-2 $2 doi
035 $a 978-3-319-22189-2
040 $a GP $c GP
041 0 $a eng
050 4 $a R853.C55
072 7 $a MJCL $2 bicssc
072 7 $a MED062000 $2 bisacsh
082 0 4 $a 616.027 $2 23
090 $a R853.C55 $b P187 2015
245 0 0 $a Pan-cancer integrative molecular portrait towards a new paradigm in precision medicine $h [electronic resource] / $c edited by Christophe Le Tourneau, Maud Kamal.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2015.
300 $a x, 144 p. : $b ill. (some col.), digital ; $c 24 cm.
505 0 $a Introduction: Rationale for Precision Medicine Clinical Trials -- The Key Role of Pathology in the Context of Precision Medicine Trials -- Basis for Molecular Genetics in Cancer -- Microarrays Based Molecular Profiling to Identify Genomic Alterations -- High Throughput Technologies: DNA and RNA Sequencing Strategies and Potential -- Bioinformatics for Precision Medicine in Oncology -- Assessment of Biomarkers' Predictive Value of Efficacy -- Designs for Evaluating Precision Medicine Trials -- Conclusions and Perspectives: Challenges for the Clinical Implementation of Precision Medicine Trials.
520 $a This original book provides readers with an overview of the latest developments in personalized medicine clinical trials in oncology. The topics covered range from the rationale behind this new generation of clinical trials and the latest statistical models for high-throughput molecular techniques, bioinformatics, high-throughput screening molecular techniques and the challenges entailed by implementing them in daily practice. It also covers the key role of pathology in the validation of molecular results and the complex assessment of predictive biomarkers. The different topics covered are supplemented by unique concrete examples based on the SHIVA trial. The authors are all members of the French Curie Institute, one of the world's foremost cancer research institutions.
650 0 $a Clinical trials. $3 181901
650 0 $a Cancer $x Molecular aspects. $3 221221
650 0 $a Cancer $x Genetic aspects. $3 189391
650 1 4 $a Medicine& Public Health. $3 729340
650 2 4 $a Oncology. $3 195181
650 2 4 $a Pathology. $3 196513
650 2 4 $a Cancer Research. $3 273660
650 2 4 $a Molecular Medicine. $3 273932
700 1 $a Le Tourneau, Christophe. $3 729338
700 1 $a Kamal, Maud. $3 729339
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-22189-2
950 $a Medicine (Springer-11650)