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Electrophysiology of unconventional ...

Delcour, Anne H.

Electrophysiology of unconventional channels and pores

Record Type:	Electronic resources : Monograph/item
Title/Author:	Electrophysiology of unconventional channels and poresedited by Anne H. Delcour.
other author:	Delcour, Anne H.
Published:	Cham :Springer International Publishing :2015.
Description:	xi, 385 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Electrophysiology.
Online resource:	http://dx.doi.org/10.1007/978-3-319-20149-8
ISBN:	9783319201498$q(electronic bk.)

Electrophysiology of unconventional channels and pores
Electrophysiology of unconventional channels and pores[electronic resource] /edited by Anne H. Delcour. - Cham :Springer International Publishing :2015. - xi, 385 p. :ill., digital ;24 cm. - Springer series in biophysics,180932-2353 ;. - Springer series in biophysics ;16..

Part I Mitochondria -- Function and regulation of mitochondrial voltage-dependent anion channel -- Mitochondrial Protein Import Channels -- Electrophysiology of the mitochondrial apoptosis-induced channel, MAC -- Ceramide Channels -- Part II Bacteria and viruses -- Bacterial Porins -- Electrophysiology of Bacterial Translocons -- Viroporins -- Part III Toxins and antimicrobial peptides -- Pore-forming colicins- unusual ion channels -unusually regulated -- Anthrax Toxin Protective Antigen Forms an Unusual Channel that Unfolds and Translocates Proteins Across Membranes -- Staphylococcal b-barrel Pore-forming Toxins: Mushrooms That Breach the Greasy Barrier -- Properties of pores formed by cholesterol-dependent cytolysins and actinoporins -- Part IV Other unconventional channels -- Perforins -- Gap Junction Channels: The electrical conduit of the intercellular world -- Amyloid Peptide Channels -- From phototaxis to biomedical applications: Investigating the molecular mechanism of channelrhodopsins.

This book is dedicated to the channels and pores that belong to an eclectic and ubiquitous class of unconventional - perhaps at times strange - pore-forming molecules, which nevertheless play fundamental roles in various organisms. These non-canonical channels may take on various and sometimes complex architectures, such as large beta-barrels or lipid-containing pores. They may originate from bacteria, viruses or intracellular organelles. For some of them, the physiologically relevant substrate may indeed be ions, and for others folded polypeptides. Some are released by cells in a soluble form that has the ability to insert into biological membranes to exert its permeabilizing effect. Many of these unconventional pores have been investigated by electrophysiology, which, by its virtue of focusing on a few or even a single unit, has provided invaluable insight into the mechanisms and structure-function relationships of these remarkable membrane entities. The chapters of this book highlight a representative set of these interesting investigations.

ISBN: 9783319201498$q(electronic bk.)

Standard No.: 10.1007/978-3-319-20149-8doiSubjects--Topical Terms:

189030
Electrophysiology.

LC Class. No.: QH517

Dewey Class. No.: 571.47

Electrophysiology of unconventional channels and pores
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505 0 $a Part I Mitochondria -- Function and regulation of mitochondrial voltage-dependent anion channel -- Mitochondrial Protein Import Channels -- Electrophysiology of the mitochondrial apoptosis-induced channel, MAC -- Ceramide Channels -- Part II Bacteria and viruses -- Bacterial Porins -- Electrophysiology of Bacterial Translocons -- Viroporins -- Part III Toxins and antimicrobial peptides -- Pore-forming colicins- unusual ion channels -unusually regulated -- Anthrax Toxin Protective Antigen Forms an Unusual Channel that Unfolds and Translocates Proteins Across Membranes -- Staphylococcal b-barrel Pore-forming Toxins: Mushrooms That Breach the Greasy Barrier -- Properties of pores formed by cholesterol-dependent cytolysins and actinoporins -- Part IV Other unconventional channels -- Perforins -- Gap Junction Channels: The electrical conduit of the intercellular world -- Amyloid Peptide Channels -- From phototaxis to biomedical applications: Investigating the molecular mechanism of channelrhodopsins.
520 $a This book is dedicated to the channels and pores that belong to an eclectic and ubiquitous class of unconventional - perhaps at times strange - pore-forming molecules, which nevertheless play fundamental roles in various organisms. These non-canonical channels may take on various and sometimes complex architectures, such as large beta-barrels or lipid-containing pores. They may originate from bacteria, viruses or intracellular organelles. For some of them, the physiologically relevant substrate may indeed be ions, and for others folded polypeptides. Some are released by cells in a soluble form that has the ability to insert into biological membranes to exert its permeabilizing effect. Many of these unconventional pores have been investigated by electrophysiology, which, by its virtue of focusing on a few or even a single unit, has provided invaluable insight into the mechanisms and structure-function relationships of these remarkable membrane entities. The chapters of this book highlight a representative set of these interesting investigations.
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