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Advances in cancer biomarkersfrom bi...

Scatena, Roberto.

Advances in cancer biomarkersfrom biochemistry to clinic for a critical revision /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Advances in cancer biomarkersedited by Roberto Scatena.
Reminder of title:	from biochemistry to clinic for a critical revision /
other author:	Scatena, Roberto.
Published:	Dordrecht :Springer Netherlands :2015.
Description:	ix, 372 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Cancer.
Online resource:	http://dx.doi.org/10.1007/978-94-017-7215-0
ISBN:	9789401772150$q(electronic bk.)

Advances in cancer biomarkersfrom biochemistry to clinic for a critical revision /
Advances in cancer biomarkersfrom biochemistry to clinic for a critical revision /[electronic resource] :edited by Roberto Scatena. - Dordrecht :Springer Netherlands :2015. - ix, 372 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v.8670065-2598 ;. - Advances in experimental medicine and biology ;946..

Prelims -- I Generality -- II Tumor markers-a critical revision -- Enzymes -- Hormones -- Oncofetal proteins -- Cytokeratins -- Carbohydrate markers -- Blood group antigens -- Genetic markers -- Various protein markers -- III Perspectives -- The role of Circulating tumor Cells as tumor markers -- Index.

At present there are a growing number of biomolecules under investigation to understand their potential role as cancer biomarker for diagnostic, prognostic and therapeutic purposes. Intriguingly, the state of art on cancer biomarkers research shows interesting and promising results together to clamorous failures. Also from a clinical point of view, there are contradictory results on routine clinical use of the present cancer biomarkers. Some patients may be simply monitored in their course by a periodic blood sample, but sometimes this monitoring shows dramatic limits. A lot of patients show serious and extensive relapses without significant change in serum concentrations of biomarkers tested. Often the physician who should utilize these biomarker does not entirely know their limits and the total potential applications as well and sometimes this knowledge is influenced by economical and marketing strategies. This limited and "polluted" knowledge may have dramatic consequences for patient. The aim of this book is to diffuse all aspects of cancer biomarkers, from their biochemical peculiarities to all clinical implications by passing through their physiology and pathophysiology. This critical approach towards old and new cancer biomarkers should foster a deepened and useful understanding of the diagnostic and prognostic index of these fundamental parameters of laboratory medicine and in the same time facilitating the research of new and more sensitive-specific signals of the cancer cell proliferation.

ISBN: 9789401772150$q(electronic bk.)

Standard No.: 10.1007/978-94-017-7215-0doiSubjects--Topical Terms:

195182
Cancer.

LC Class. No.: RC267

Dewey Class. No.: 616.9940072

Advances in cancer biomarkersfrom biochemistry to clinic for a critical revision /
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520 $a At present there are a growing number of biomolecules under investigation to understand their potential role as cancer biomarker for diagnostic, prognostic and therapeutic purposes. Intriguingly, the state of art on cancer biomarkers research shows interesting and promising results together to clamorous failures. Also from a clinical point of view, there are contradictory results on routine clinical use of the present cancer biomarkers. Some patients may be simply monitored in their course by a periodic blood sample, but sometimes this monitoring shows dramatic limits. A lot of patients show serious and extensive relapses without significant change in serum concentrations of biomarkers tested. Often the physician who should utilize these biomarker does not entirely know their limits and the total potential applications as well and sometimes this knowledge is influenced by economical and marketing strategies. This limited and "polluted" knowledge may have dramatic consequences for patient. The aim of this book is to diffuse all aspects of cancer biomarkers, from their biochemical peculiarities to all clinical implications by passing through their physiology and pathophysiology. This critical approach towards old and new cancer biomarkers should foster a deepened and useful understanding of the diagnostic and prognostic index of these fundamental parameters of laboratory medicine and in the same time facilitating the research of new and more sensitive-specific signals of the cancer cell proliferation.
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