語系:
繁體中文
English
說明(常見問題)
圖資館首頁
登入
回首頁
切換:
標籤
|
MARC模式
|
ISBD
Organic cation transportersintegrati...
~
Ciarimboli, Giuliano.
Organic cation transportersintegration of physiology, pathology, and pharmacology /
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Organic cation transportersedited by Giuliano Ciarimboli, Sophie Gautron, Eberhard Schlatter.
其他題名:
integration of physiology, pathology, and pharmacology /
其他作者:
Ciarimboli, Giuliano.
出版者:
Cham :Springer International Publishing :2016.
面頁冊數:
xv, 264 p. :ill., digital ;24 cm.
Contained By:
Springer eBooks
標題:
Carrier proteins.
電子資源:
http://dx.doi.org/10.1007/978-3-319-23793-0
ISBN:
9783319237930$q(electronic bk.)
Organic cation transportersintegration of physiology, pathology, and pharmacology /
Organic cation transporters
integration of physiology, pathology, and pharmacology /[electronic resource] :edited by Giuliano Ciarimboli, Sophie Gautron, Eberhard Schlatter. - Cham :Springer International Publishing :2016. - xv, 264 p. :ill., digital ;24 cm.
Introduction to the cellular transport of organic cations -- Functional properties of organic cation transporter OCT1, binding of substrates and inhibitors, and presumed transport mechanism -- Pharmacological and toxicological significance of the organic cation transporters OCT and MATE: Drug disposition, interaction and toxicity -- Genetic variability in organic cation transporters: pathophysiological manifestations and consequences for drug pharmacokinetics and efficacy -- Physiological and pathological regulation of transporters for organic cations -- Endocrine and metabolic regulation of transporters for organic cations -- Organic cation transporters (OCTs) as modulators of behavior and mood -- Organic cation transporters as modulators of neurodegeneration and neuroprotection -- Translational relevance of animal models for the study of organic cation transporter function -- Role of transporters for organic cations in plants for environmental cycling of pharmaceutical residues.
This innovative text explores the cellular transport of organic cations, from functional and structural properties to pharmacological implications and psychiatric developments. The authoritative chapters introduce organic cation transporters and then proceed to discuss their mechanisms such as binding of substrates and inhibitors; their drug dispositions and toxicity; their relationships to genetic and pathophysiological variability; and their roles in endocrine, metabolic, and neurological systems. The final chapters delve into the use of animal models for the study of organic cation transporter function and their possible use in environmental cycling of pharmaceutical residues. This comprehensive volume unites integrative transporter physiology with structural and molecular biology, genetics, pharmacology and pathophysiology, offering a holistic approach to utilizing this novel technique in physiological contexts. It will prove invaluable reading for researchers and students in various areas of integrative, organ, cell and molecular physiology as well as pharmacologists and neurologists.
ISBN: 9783319237930$q(electronic bk.)
Standard No.: 10.1007/978-3-319-23793-0doiSubjects--Topical Terms:
194483
Carrier proteins.
LC Class. No.: QP552.C34
Dewey Class. No.: 572.696
Organic cation transportersintegration of physiology, pathology, and pharmacology /
LDR
:03119nmm a2200313 a 4500
001
482131
003
DE-He213
005
20160803144947.0
006
m d
007
cr nn 008maaau
008
161007s2016 gw s 0 eng d
020
$a
9783319237930$q(electronic bk.)
020
$a
9783319237923$q(paper)
024
7
$a
10.1007/978-3-319-23793-0
$2
doi
035
$a
978-3-319-23793-0
040
$a
GP
$c
GP
041
0
$a
eng
050
4
$a
QP552.C34
072
7
$a
MFG
$2
bicssc
072
7
$a
MED075000
$2
bisacsh
082
0 4
$a
572.696
$2
23
090
$a
QP552.C34
$b
O68 2016
245
0 0
$a
Organic cation transporters
$h
[electronic resource] :
$b
integration of physiology, pathology, and pharmacology /
$c
edited by Giuliano Ciarimboli, Sophie Gautron, Eberhard Schlatter.
260
$a
Cham :
$b
Springer International Publishing :
$b
Imprint: Springer,
$c
2016.
300
$a
xv, 264 p. :
$b
ill., digital ;
$c
24 cm.
505
0
$a
Introduction to the cellular transport of organic cations -- Functional properties of organic cation transporter OCT1, binding of substrates and inhibitors, and presumed transport mechanism -- Pharmacological and toxicological significance of the organic cation transporters OCT and MATE: Drug disposition, interaction and toxicity -- Genetic variability in organic cation transporters: pathophysiological manifestations and consequences for drug pharmacokinetics and efficacy -- Physiological and pathological regulation of transporters for organic cations -- Endocrine and metabolic regulation of transporters for organic cations -- Organic cation transporters (OCTs) as modulators of behavior and mood -- Organic cation transporters as modulators of neurodegeneration and neuroprotection -- Translational relevance of animal models for the study of organic cation transporter function -- Role of transporters for organic cations in plants for environmental cycling of pharmaceutical residues.
520
$a
This innovative text explores the cellular transport of organic cations, from functional and structural properties to pharmacological implications and psychiatric developments. The authoritative chapters introduce organic cation transporters and then proceed to discuss their mechanisms such as binding of substrates and inhibitors; their drug dispositions and toxicity; their relationships to genetic and pathophysiological variability; and their roles in endocrine, metabolic, and neurological systems. The final chapters delve into the use of animal models for the study of organic cation transporter function and their possible use in environmental cycling of pharmaceutical residues. This comprehensive volume unites integrative transporter physiology with structural and molecular biology, genetics, pharmacology and pathophysiology, offering a holistic approach to utilizing this novel technique in physiological contexts. It will prove invaluable reading for researchers and students in various areas of integrative, organ, cell and molecular physiology as well as pharmacologists and neurologists.
650
0
$a
Carrier proteins.
$3
194483
650
0
$a
Cations.
$3
738659
650
1 4
$a
Biomedicine.
$3
273648
650
2 4
$a
Human Physiology.
$3
274509
650
2 4
$a
Pharmacology/Toxicology.
$3
273652
650
2 4
$a
Pathology.
$3
196513
700
1
$a
Ciarimboli, Giuliano.
$3
738656
700
1
$a
Gautron, Sophie.
$3
738657
700
1
$a
Schlatter, Eberhard.
$3
738658
710
2
$a
SpringerLink (Online service)
$3
273601
773
0
$t
Springer eBooks
856
4 0
$u
http://dx.doi.org/10.1007/978-3-319-23793-0
950
$a
Biomedical and Life Sciences (Springer-11642)
筆 0 讀者評論
全部
電子館藏
館藏
1 筆 • 頁數 1 •
1
條碼號
館藏地
館藏流通類別
資料類型
索書號
使用類型
借閱狀態
預約狀態
備註欄
附件
000000121968
電子館藏
1圖書
電子書
EB QP552.C34 O68 2016
一般使用(Normal)
在架
0
1 筆 • 頁數 1 •
1
多媒體
多媒體檔案
http://dx.doi.org/10.1007/978-3-319-23793-0
評論
新增評論
分享你的心得
Export
取書館別
處理中
...
變更密碼
登入