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Surface-enhanced raman spectroscopyb...

Prochazka, Marek.

Surface-enhanced raman spectroscopybioanalytical, biomolecular and medical applications /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Surface-enhanced raman spectroscopyby Marek Prochazka.
Reminder of title:	bioanalytical, biomolecular and medical applications /
Author:	Prochazka, Marek.
Published:	Cham :Springer International Publishing :2016.
Description:	xvi, 221 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Raman spectroscopy.
Online resource:	http://dx.doi.org/10.1007/978-3-319-23992-7
ISBN:	9783319239927$q(electronic bk.)

Surface-enhanced raman spectroscopybioanalytical, biomolecular and medical applications /
Prochazka, Marek.

Surface-enhanced raman spectroscopybioanalytical, biomolecular and medical applications /[electronic resource] :by Marek Prochazka. - Cham :Springer International Publishing :2016. - xvi, 221 p. :ill., digital ;24 cm. - Biological and medical physics, biomedical engineering,1618-7210. - Biological and medical physics, biomedical engineering..

This book gives an overview of recent developments in RS and SERS for sensing and biosensing considering also limitations, possibilities and prospects of this technique. Raman scattering (RS) is a widely used vibrational technique providing highly specific molecular spectral patterns. A severe limitation for the application of this spectroscopic technique lies in the low cross section of RS. Surface-enhanced Raman scattering (SERS) spectroscopy overcomes this problem by 6-11 orders of magnitude enhancement compared with the standard RS for molecules in the close vicinity of certain rough metal surfaces. Thus, SERS combines molecular fingerprint specificity with potential single-molecule sensitivity. Due to the recent development of new SERS-active substrates, labeling and derivatization chemistry as well as new instrumentations, SERS became a very promising tool for many varied applications, including bioanalytical studies and sensing. Both intrinsic and extrinsic SERS biosensing schemes have been employed to detect and identify small molecules, nucleic acids and proteins, and also for cellular and in vivo sensing.

ISBN: 9783319239927$q(electronic bk.)

Standard No.: 10.1007/978-3-319-23992-7doiSubjects--Topical Terms:

194325
Raman spectroscopy.

LC Class. No.: QD96.R34

Dewey Class. No.: 543.57

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520 $a This book gives an overview of recent developments in RS and SERS for sensing and biosensing considering also limitations, possibilities and prospects of this technique. Raman scattering (RS) is a widely used vibrational technique providing highly specific molecular spectral patterns. A severe limitation for the application of this spectroscopic technique lies in the low cross section of RS. Surface-enhanced Raman scattering (SERS) spectroscopy overcomes this problem by 6-11 orders of magnitude enhancement compared with the standard RS for molecules in the close vicinity of certain rough metal surfaces. Thus, SERS combines molecular fingerprint specificity with potential single-molecule sensitivity. Due to the recent development of new SERS-active substrates, labeling and derivatization chemistry as well as new instrumentations, SERS became a very promising tool for many varied applications, including bioanalytical studies and sensing. Both intrinsic and extrinsic SERS biosensing schemes have been employed to detect and identify small molecules, nucleic acids and proteins, and also for cellular and in vivo sensing.
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