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Systemic sclerosis

Fujimoto, Manabu.

Systemic sclerosis

Record Type:	Electronic resources : Monograph/item
Title/Author:	Systemic sclerosisedited by Kazuhiko Takehara, Manabu Fujimoto, Masataka Kuwana.
other author:	Takehara, Kazuhiko.
Published:	Tokyo :Springer Japan :2016.
Description:	viii, 247 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Systemic scleroderma.
Online resource:	http://dx.doi.org/10.1007/978-4-431-55708-1
ISBN:	9784431557081$q(electronic bk.)

Systemic sclerosis
Systemic sclerosis[electronic resource] /edited by Kazuhiko Takehara, Manabu Fujimoto, Masataka Kuwana. - Tokyo :Springer Japan :2016. - viii, 247 p. :ill., digital ;24 cm.

1 -- Fibrosis: overview 2 -- Autoimmunity in systemic sclerosis: Overview 3 -- Endothelial progenitor cell 4 -- Animal models of systemic sclerosis 5 -- Genetics of Systemic Sclerosis 6 -- Role of the Interleukin-1 Family in the Fibrogenic Phenotype in Systemic Sclerosis 7 -- Interleukin-6 in the Pathogenesis of Systemic Sclerosis 8 -- Epigenetics 9 -- Transforming Growth Factor-ß and Connective Tissue Growth Factor 10 -- Endothelin 11 -- The Role of B cells in Systemic Sclerosis 12 -- Fli1 13 -- Biomarker 14 -- Autoantibodies in Systemic Sclerosis.

This book provides a comprehensive review of the recent advances in the research of systemic sclerosis (scleroderma) Systemic sclerosis is a complex autoimmune disease characterized by vasculopathy, fibrosis, and immune activation. This disease is also associated with certain susceptibility genes and is affected by epigenetic regulation. Recent studies have revealed a variety of new evidence suggestive of the pathogenesis of the disease. These include endothelial progenitor cells, cytokines and growth factors, and B cells. Studies using animal models have also provided novel insight into the pathomechanisms. In addition to these topics, the book covers clinical research regarding biomarkers and autoantibodies. This volume will benefit all rheumatologists and dermatologists as well as basic scientists, especially immunologists, molecular biologists, and biochemists.

ISBN: 9784431557081$q(electronic bk.)

Standard No.: 10.1007/978-4-431-55708-1doiSubjects--Topical Terms:

560673
Systemic scleroderma.

LC Class. No.: RC924.5.S34

Dewey Class. No.: 616.77

Systemic sclerosis
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245 0 0 $a Systemic sclerosis $h [electronic resource] / $c edited by Kazuhiko Takehara, Manabu Fujimoto, Masataka Kuwana.
260 $a Tokyo : $b Springer Japan : $b Imprint: Springer, $c 2016.
300 $a viii, 247 p. : $b ill., digital ; $c 24 cm.
505 0 $a 1 -- Fibrosis: overview 2 -- Autoimmunity in systemic sclerosis: Overview 3 -- Endothelial progenitor cell 4 -- Animal models of systemic sclerosis 5 -- Genetics of Systemic Sclerosis 6 -- Role of the Interleukin-1 Family in the Fibrogenic Phenotype in Systemic Sclerosis 7 -- Interleukin-6 in the Pathogenesis of Systemic Sclerosis 8 -- Epigenetics 9 -- Transforming Growth Factor-ß and Connective Tissue Growth Factor 10 -- Endothelin 11 -- The Role of B cells in Systemic Sclerosis 12 -- Fli1 13 -- Biomarker 14 -- Autoantibodies in Systemic Sclerosis.
520 $a This book provides a comprehensive review of the recent advances in the research of systemic sclerosis (scleroderma) Systemic sclerosis is a complex autoimmune disease characterized by vasculopathy, fibrosis, and immune activation. This disease is also associated with certain susceptibility genes and is affected by epigenetic regulation. Recent studies have revealed a variety of new evidence suggestive of the pathogenesis of the disease. These include endothelial progenitor cells, cytokines and growth factors, and B cells. Studies using animal models have also provided novel insight into the pathomechanisms. In addition to these topics, the book covers clinical research regarding biomarkers and autoantibodies. This volume will benefit all rheumatologists and dermatologists as well as basic scientists, especially immunologists, molecular biologists, and biochemists.
650 0 $a Systemic scleroderma. $3 560673
650 0 $a Systemic scleroderma $x Research. $3 741105
650 1 4 $a Medicine & Public Health. $3 273799
650 2 4 $a Dermatology. $3 274951
650 2 4 $a Rheumatology. $3 276701
650 2 4 $a Internal Medicine. $3 273839
700 1 $a Takehara, Kazuhiko. $3 741102
700 1 $a Fujimoto, Manabu. $3 741103
700 1 $a Kuwana, Masataka. $3 741104
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-4-431-55708-1
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