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Cancer and zebrafishmechanisms, tech...

Langenau, David M.

Cancer and zebrafishmechanisms, techniques, and models /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Cancer and zebrafishedited by David M. Langenau.
Reminder of title:	mechanisms, techniques, and models /
other author:	Langenau, David M.
Published:	Cham :Springer International Publishing :2016.
Description:	xii, 552 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	CancerAnimal models.
Online resource:	http://dx.doi.org/10.1007/978-3-319-30654-4
ISBN:	9783319306544$q(electronic bk.)

Cancer and zebrafishmechanisms, techniques, and models /
Cancer and zebrafishmechanisms, techniques, and models /[electronic resource] :edited by David M. Langenau. - Cham :Springer International Publishing :2016. - xii, 552 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v.9160065-2598 ;. - Advances in experimental medicine and biology ;946..

Part 1. Powers Of The Zebrafish Model -- 1. Uncharted Waters: Zebrafish Cancer Models Navigate A Course for Oncogene Discovery -- 2. The Toolbox for Conditional Zebrafish Cancer Models -- 3. Approaches to Inactivate Genes in Zebrafish -- 4. Tumor Suppressors in Zebrafish: From Tp53 To Pten and Beyond -- 5. Identifying Novel Cancer Therapies Using Chemical Genetics and Zebrafish -- 6. Genomic Approaches To Zebrafish Cancer -- 7. Transcriptomic Analyses in Zebrafish Cancer Models for Global Gene Expression and Pathway Discovery -- 8. Zebrafish Discoveries in Cancer Epigenetics -- 9. Lymphatics, Cancer and Zebrafish -- 10. In Vivo Imaging of Cancer in Zebrafish -- 11. Imaging Cancer Angiogenesis and Metastasis in A Zebrafish Embryo Model -- 12. Allograft Cancer Cell Transplantation in Zebrafish -- 13. The Zebrafish Xenograft Platform: Evolution of A Novel Cancer Model and Preclinical Screening Tool -- 14. Automation of Technology for Cancer Research -- Part 2. Cancer Models in Fish -- 15. Zebrafish Models Of Human Leukemia: Technological Advances and Mechanistic Insights -- 16. Zebrafish Rhabdomyosarcoma -- 17. Baiting for Cancer: Using The Zebrafish as A Model in Liver And Pancreatic Cancer -- 18. How Zebrafish Are Helping Us To Target Colorectal Cancer -- 19. Zebrafish Melanoma -- 20. Neuroblastoma and Its Zebrafish Model -- 21. Zebrafish Germ Cell Tumors -- 22. Malignant Peripheral Nerve Sheath Tumors -- 23. Xiphophorus and Medaka Cancer Models.

This volume focuses on defining the unique attributes of using the zebrafish cancer model for discovering important pathways and potential drug targets for the treatment of human cancers. Using the zebrafish model, the volume explores oncogene and tumor suppressor discovery, chemical genetic approaches, genomics, epigenetics, cancer imaging, and cell transplantation. Contributed chapters come from the most prominent laboratories working in this field, which provides a unique perspective on zebrafish models from a wide spectrum of the research community. In addition, the book offers a detailed analysis of the most current research in the area for specific zebrafish cancer models, including T cell leukemia, rhabdomyosarcoma, liver and pancreatic cancer, melanoma, neuroblastoma, germ cell tumors, and malignant peripheral sheath tumors. A chapter is also dedicated to the development and utilization of other piscine models of cancer. The compilation of chapters in the volume culminates into a comprehensive and definitive text on zebrafish and cancer, providing a much needed resource on the powerful attributes of the zebrafish model system.

ISBN: 9783319306544$q(electronic bk.)

Standard No.: 10.1007/978-3-319-30654-4doiSubjects--Topical Terms:

339067
Cancer
--Animal models.

LC Class. No.: RC267

Dewey Class. No.: 616.994027

Cancer and zebrafishmechanisms, techniques, and models /
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245 1 0 $a Cancer and zebrafish $h [electronic resource] : $b mechanisms, techniques, and models / $c edited by David M. Langenau.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2016.
300 $a xii, 552 p. : $b ill., digital ; $c 24 cm.
490 1 $a Advances in experimental medicine and biology, $x 0065-2598 ; $v v.916
505 0 $a Part 1. Powers Of The Zebrafish Model -- 1. Uncharted Waters: Zebrafish Cancer Models Navigate A Course for Oncogene Discovery -- 2. The Toolbox for Conditional Zebrafish Cancer Models -- 3. Approaches to Inactivate Genes in Zebrafish -- 4. Tumor Suppressors in Zebrafish: From Tp53 To Pten and Beyond -- 5. Identifying Novel Cancer Therapies Using Chemical Genetics and Zebrafish -- 6. Genomic Approaches To Zebrafish Cancer -- 7. Transcriptomic Analyses in Zebrafish Cancer Models for Global Gene Expression and Pathway Discovery -- 8. Zebrafish Discoveries in Cancer Epigenetics -- 9. Lymphatics, Cancer and Zebrafish -- 10. In Vivo Imaging of Cancer in Zebrafish -- 11. Imaging Cancer Angiogenesis and Metastasis in A Zebrafish Embryo Model -- 12. Allograft Cancer Cell Transplantation in Zebrafish -- 13. The Zebrafish Xenograft Platform: Evolution of A Novel Cancer Model and Preclinical Screening Tool -- 14. Automation of Technology for Cancer Research -- Part 2. Cancer Models in Fish -- 15. Zebrafish Models Of Human Leukemia: Technological Advances and Mechanistic Insights -- 16. Zebrafish Rhabdomyosarcoma -- 17. Baiting for Cancer: Using The Zebrafish as A Model in Liver And Pancreatic Cancer -- 18. How Zebrafish Are Helping Us To Target Colorectal Cancer -- 19. Zebrafish Melanoma -- 20. Neuroblastoma and Its Zebrafish Model -- 21. Zebrafish Germ Cell Tumors -- 22. Malignant Peripheral Nerve Sheath Tumors -- 23. Xiphophorus and Medaka Cancer Models.
520 $a This volume focuses on defining the unique attributes of using the zebrafish cancer model for discovering important pathways and potential drug targets for the treatment of human cancers. Using the zebrafish model, the volume explores oncogene and tumor suppressor discovery, chemical genetic approaches, genomics, epigenetics, cancer imaging, and cell transplantation. Contributed chapters come from the most prominent laboratories working in this field, which provides a unique perspective on zebrafish models from a wide spectrum of the research community. In addition, the book offers a detailed analysis of the most current research in the area for specific zebrafish cancer models, including T cell leukemia, rhabdomyosarcoma, liver and pancreatic cancer, melanoma, neuroblastoma, germ cell tumors, and malignant peripheral sheath tumors. A chapter is also dedicated to the development and utilization of other piscine models of cancer. The compilation of chapters in the volume culminates into a comprehensive and definitive text on zebrafish and cancer, providing a much needed resource on the powerful attributes of the zebrafish model system.
650 0 $a Cancer $x Animal models. $3 339067
650 0 $a Cancer $x Genetic aspects. $3 189391
650 1 4 $a Biomedicine. $3 273648
650 2 4 $a Cancer Research. $3 273660
650 2 4 $a Gene Function. $3 456568
650 2 4 $a Animal Anatomy / Morphology / Histology. $3 277742
700 1 $a Langenau, David M. $3 747197
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830 0 $a Advances in experimental medicine and biology ; $v 946. $3 557559
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-30654-4
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