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Molecular radio-oncology

Baumann, Michael.

Molecular radio-oncology

Record Type:	Electronic resources : Monograph/item
Title/Author:	Molecular radio-oncologyedited by Michael Baumann, Mechthild Krause, Nils Cordes.
other author:	Baumann, Michael.
Published:	Berlin, Heidelberg :Springer Berlin Heidelberg :2016.
Description:	ix, 201 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer eBooks
Subject:	CancerMolecular aspects.
Online resource:	http://dx.doi.org/10.1007/978-3-662-49651-0
ISBN:	9783662496510$q(electronic bk.)

Molecular radio-oncology
Molecular radio-oncology[electronic resource] /edited by Michael Baumann, Mechthild Krause, Nils Cordes. - Berlin, Heidelberg :Springer Berlin Heidelberg :2016. - ix, 201 p. :ill. (some col.), digital ;24 cm. - Recent results in cancer research,v.1980080-0015 ;. - Recent results in cancer research ;v.192..

Molecular Radiobiology: Hypoxia -- Molecular Targeting of Growth Factor Receptor Signaling -- Molecular Targeting of Cell Adhesion Molecules -- Tumor Pathophysiology -- DNA Repair -- Cancer Stem Cells -- Normal Tissue. Biomarkers/Personalized Radiation Oncology: EGFR and other RTKs -- HPV -- Hypoxia -- Study design for Biomarker research in radiation oncology -- Gene expression/system biology. Molecular Imaging in Radiation Oncology:FMISO as a biomarker for clinical radiation oncology -- FDG and beyond -- Molecular imaging techniques beyond PET.

This book concisely reviews our current understanding of hypoxia, molecular targeting, DNA repair, cancer stem cells, and tumor pathophysiology, while also discussing novel strategies for putting these findings into practice in daily clinical routine. Radiotherapy is an important part of modern multimodal cancer treatment, and the past several years have witnessed not only substantial improvements in radiation techniques and the use of new beam qualities, but also major strides in our understanding of molecular tumor biology and tumor radiation response. Against this backdrop, the book highlights recent efforts to identify reasonable and clinically applicable biomarkers using broad-spectrum tissue microarrays and high-throughput systems biology approaches like genomics and epigenomics. In particular, it describes in detail how such molecular information is now being exploited for diagnostic imaging and imaging throughout treatment using the example of positron emission tomography. By discussing all these issues in the context of modern radiation oncology, the book provides a broad, up-to-date overview of the molecular aspects of radiation oncology that will hopefully foster its further optimization.

ISBN: 9783662496510$q(electronic bk.)

Standard No.: 10.1007/978-3-662-49651-0doiSubjects--Topical Terms:

221221
Cancer
--Molecular aspects.

LC Class. No.: RC268.4

Dewey Class. No.: 616.994

Molecular radio-oncology
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245 0 0 $a Molecular radio-oncology $h [electronic resource] / $c edited by Michael Baumann, Mechthild Krause, Nils Cordes.
260 $a Berlin, Heidelberg : $b Springer Berlin Heidelberg : $b Imprint: Springer, $c 2016.
300 $a ix, 201 p. : $b ill. (some col.), digital ; $c 24 cm.
490 1 $a Recent results in cancer research, $x 0080-0015 ; $v v.198
505 0 $a Molecular Radiobiology: Hypoxia -- Molecular Targeting of Growth Factor Receptor Signaling -- Molecular Targeting of Cell Adhesion Molecules -- Tumor Pathophysiology -- DNA Repair -- Cancer Stem Cells -- Normal Tissue. Biomarkers/Personalized Radiation Oncology: EGFR and other RTKs -- HPV -- Hypoxia -- Study design for Biomarker research in radiation oncology -- Gene expression/system biology. Molecular Imaging in Radiation Oncology:FMISO as a biomarker for clinical radiation oncology -- FDG and beyond -- Molecular imaging techniques beyond PET.
520 $a This book concisely reviews our current understanding of hypoxia, molecular targeting, DNA repair, cancer stem cells, and tumor pathophysiology, while also discussing novel strategies for putting these findings into practice in daily clinical routine. Radiotherapy is an important part of modern multimodal cancer treatment, and the past several years have witnessed not only substantial improvements in radiation techniques and the use of new beam qualities, but also major strides in our understanding of molecular tumor biology and tumor radiation response. Against this backdrop, the book highlights recent efforts to identify reasonable and clinically applicable biomarkers using broad-spectrum tissue microarrays and high-throughput systems biology approaches like genomics and epigenomics. In particular, it describes in detail how such molecular information is now being exploited for diagnostic imaging and imaging throughout treatment using the example of positron emission tomography. By discussing all these issues in the context of modern radiation oncology, the book provides a broad, up-to-date overview of the molecular aspects of radiation oncology that will hopefully foster its further optimization.
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650 2 4 $a Oncology. $3 195181
650 2 4 $a Imaging / Radiology. $3 274007
650 2 4 $a Molecular Medicine. $3 273932
650 2 4 $a Cancer Research. $3 273660
700 1 $a Baumann, Michael. $3 750399
700 1 $a Krause, Mechthild. $3 750400
700 1 $a Cordes, Nils. $3 750401
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