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Signal transduction

Gomperts, B. D.

Signal transduction

Record Type:	Electronic resources : Monograph/item
Title/Author:	Signal transductionIjsbrand M. Kramer.
Author:	Kramer, Ijsbrand M.
other author:	Gomperts, B. D.
Published:	Amsterdam :Academic Press,c2015.
Description:	1 online resource (xlv, 1078 p.) :ill. (chiefly col.)
Notes:	"The third edition differs considerably from the earlier editions"--Page xv.
Subject:	Cellular signal transduction.
Online resource:	click for full text
ISBN:	9780123948038 (electronic bk.)

Signal transduction
Kramer, Ijsbrand M.

Signal transduction[electronic resource] /Ijsbrand M. Kramer. - 3rd ed. - Amsterdam :Academic Press,c2015. - 1 online resource (xlv, 1078 p.) :ill. (chiefly col.)

"The third edition differs considerably from the earlier editions"--Page xv.

Includes bibliographical references and index.

Prologue : signal transduction from an historical perspective -- An introduction to signal transduction -- Regulation of muscle contraction by adrenoceptors -- Cholinergic signaling and muscle contraction -- Sensory signal processing : visual transduction and olfaction -- Intracellular calcium -- Bringing the signal into the nucleus : regulation of gene expression -- Nuclear receptors -- Protein kinase C in oncogenic transformation and cell polarity -- Regulation of cell proliferation by receptor tyrosine protein kinases -- Signal transduction to and from adhesion molecules -- WNT signaling and the regulation of cell adhesion and differentiation -- Activation of the innate immune system : the toll-like receptor-4 and signaling through ubiquitinylation -- Chemokines and traffic of white blood cells -- Activating the adaptive immune system : role of non-receptor tyrosinekinases -- Signaling through the insulin receptor : phosphoinositide 3-kinases and AKT -- TGFÃŸ and signaling through receptor serine/threonine protein kinases -- Protein phosphatases -- Cell fate determination by notch.

"A reference on cellular signaling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, growth factors and adhesion molecules. In a new chapter, an introduction to signal transduction, the book provides a concise overview of receptor mechanisms, from receptor -ligand interactions to post-translational modifications operational in the process of bringing about cellular changes. The phosphorylation process, from bacteria to men, is discussed in detail. Signal transduction third edition further elaborates on diverse signaling cascades within particular contexts suchas muscle contraction, innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic transformation and cell fate decision during development or in stem cell niches. The subjects have been enriched with descriptions of the relevant anatomical, histological,physiological or pathological condition."--Page 4 of cover.

ISBN: 9780123948038 (electronic bk.)Subjects--Topical Terms:

188626
Cellular signal transduction.

LC Class. No.: QP517.C45 / G65 2015

Dewey Class. No.: 571.7/4

National Library of Medicine Call No.: QU 375

Signal transduction
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100 1 $a Kramer, Ijsbrand M. $3 502031
245 1 0 $a Signal transduction $h [electronic resource] / $c Ijsbrand M. Kramer.
250 $a 3rd ed.
260 $a Amsterdam : $b Academic Press, $c c2015.
300 $a 1 online resource (xlv, 1078 p.) : $b ill. (chiefly col.)
500 $a "The third edition differs considerably from the earlier editions"--Page xv.
504 $a Includes bibliographical references and index.
505 0 $a Prologue : signal transduction from an historical perspective -- An introduction to signal transduction -- Regulation of muscle contraction by adrenoceptors -- Cholinergic signaling and muscle contraction -- Sensory signal processing : visual transduction and olfaction -- Intracellular calcium -- Bringing the signal into the nucleus : regulation of gene expression -- Nuclear receptors -- Protein kinase C in oncogenic transformation and cell polarity -- Regulation of cell proliferation by receptor tyrosine protein kinases -- Signal transduction to and from adhesion molecules -- WNT signaling and the regulation of cell adhesion and differentiation -- Activation of the innate immune system : the toll-like receptor-4 and signaling through ubiquitinylation -- Chemokines and traffic of white blood cells -- Activating the adaptive immune system : role of non-receptor tyrosinekinases -- Signaling through the insulin receptor : phosphoinositide 3-kinases and AKT -- TGFÃŸ and signaling through receptor serine/threonine protein kinases -- Protein phosphatases -- Cell fate determination by notch.
520 $a "A reference on cellular signaling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, growth factors and adhesion molecules. In a new chapter, an introduction to signal transduction, the book provides a concise overview of receptor mechanisms, from receptor -ligand interactions to post-translational modifications operational in the process of bringing about cellular changes. The phosphorylation process, from bacteria to men, is discussed in detail. Signal transduction third edition further elaborates on diverse signaling cascades within particular contexts suchas muscle contraction, innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic transformation and cell fate decision during development or in stem cell niches. The subjects have been enriched with descriptions of the relevant anatomical, histological,physiological or pathological condition."--Page 4 of cover.
650 0 $a Cellular signal transduction. $3 188626
650 1 2 $a Signal Transduction. $3 224779
700 1 $a Gomperts, B. D. $3 209067
856 4 0 $u http://www.sciencedirect.com/science/book/9780123948038 $z click for full text