國立高雄大學圖資館 |

Language: English

Back

Molecular and cellular mechanobiology

Chien, Shu.

Molecular and cellular mechanobiology

Record Type:	Electronic resources : Monograph/item
Title/Author:	Molecular and cellular mechanobiologyedited by Shu Chien, Adam J. Engler, Peter Yingxiao Wang.
other author:	Chien, Shu.
Published:	New York, NY :Springer New York :2016.
Description:	xiii, 302 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Biomechanics.
Online resource:	http://dx.doi.org/10.1007/978-1-4939-5617-3
ISBN:	9781493956173$q(electronic bk.)

Molecular and cellular mechanobiology
Molecular and cellular mechanobiology[electronic resource] /edited by Shu Chien, Adam J. Engler, Peter Yingxiao Wang. - New York, NY :Springer New York :2016. - xiii, 302 p. :ill. (some col.), digital ;24 cm. - Physiology in health and disease. - Physiology in health and disease..

Part 1. Mechanosensors -- The Primary Cilium as a Strain Amplifying Microdomain for Mechanotransduction at the Cell Membrane -- Vascular Endothelial Mechanosensors in Response to Fluid Shear Stress -- Cadherins in Mechanotransduction -- Perspectives of FRET Imaging to study Epigenetics and Mechanobiology in the Nucleus -- Part 2. Transducers -- Emerging Roles of YAP/TAZ in Mechanobiology -- Role of Rho GTPases in Mechanobiology -- Illuminating Cell Adhesion: Modern Microscopy Approaches to Study Integrin-Based Focal Adhesions -- Part 3. Epigenetic and Genetic Regulations in the Nucleus -- Mechanotransduction to Epigenetic Remodeling -- The Nuclear Lamina: From Mechano-Sensing in Differentiation to Cancer Cell Migration -- Role of Cell Geometry on Nuclear Mechanics, Chromosome Reorganization, and Gene Expression -- Part 4. Applications -- Mechanobiological Control of Cell Fate for Applications in Cardiovascular Regenerative Medicine -- Heart Valve Mechanobiology in Development and Disease -- Molecular and Cellular Mechanobiology of Cancer.

This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological regulation of cellular functions will be explored, as well as applications to pathophysiological states in disease. A comprehensive understanding of the roles of physicochemical microenvironment and intracellular responses in determining cellular function in health and disease will also be discussed.

ISBN: 9781493956173$q(electronic bk.)

Standard No.: 10.1007/978-1-4939-5617-3doiSubjects--Topical Terms:

188942
Biomechanics.

LC Class. No.: QH513

Dewey Class. No.: 571.43

Molecular and cellular mechanobiology
LDR:02774nmm a2200325 a 4500 001 495845
003 DE-He213
005 20160810153448.0
006 m d
007 cr nn 008maaau
008 170323s2016 nyu s 0 eng d
020 $a 9781493956173$q(electronic bk.)
020 $a 9781493956159$q(paper)
024 7 $a 10.1007/978-1-4939-5617-3 $2 doi
035 $a 978-1-4939-5617-3
040 $a GP $c GP
041 0 $a eng
050 4 $a QH513
072 7 $a MFG $2 bicssc
072 7 $a MED075000 $2 bisacsh
082 0 4 $a 571.43 $2 23
090 $a QH513 $b .M718 2016
245 0 0 $a Molecular and cellular mechanobiology $h [electronic resource] / $c edited by Shu Chien, Adam J. Engler, Peter Yingxiao Wang.
260 $a New York, NY : $b Springer New York : $b Imprint: Springer, $c 2016.
300 $a xiii, 302 p. : $b ill. (some col.), digital ; $c 24 cm.
490 1 $a Physiology in health and disease
505 0 $a Part 1. Mechanosensors -- The Primary Cilium as a Strain Amplifying Microdomain for Mechanotransduction at the Cell Membrane -- Vascular Endothelial Mechanosensors in Response to Fluid Shear Stress -- Cadherins in Mechanotransduction -- Perspectives of FRET Imaging to study Epigenetics and Mechanobiology in the Nucleus -- Part 2. Transducers -- Emerging Roles of YAP/TAZ in Mechanobiology -- Role of Rho GTPases in Mechanobiology -- Illuminating Cell Adhesion: Modern Microscopy Approaches to Study Integrin-Based Focal Adhesions -- Part 3. Epigenetic and Genetic Regulations in the Nucleus -- Mechanotransduction to Epigenetic Remodeling -- The Nuclear Lamina: From Mechano-Sensing in Differentiation to Cancer Cell Migration -- Role of Cell Geometry on Nuclear Mechanics, Chromosome Reorganization, and Gene Expression -- Part 4. Applications -- Mechanobiological Control of Cell Fate for Applications in Cardiovascular Regenerative Medicine -- Heart Valve Mechanobiology in Development and Disease -- Molecular and Cellular Mechanobiology of Cancer.
520 $a This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological regulation of cellular functions will be explored, as well as applications to pathophysiological states in disease. A comprehensive understanding of the roles of physicochemical microenvironment and intracellular responses in determining cellular function in health and disease will also be discussed.
650 0 $a Biomechanics. $3 188942
650 1 4 $a Biomedicine. $3 273648
650 2 4 $a Human Physiology. $3 274509
650 2 4 $a Cell Physiology. $3 238835
650 2 4 $a Atomic/Molecular Structure and Spectra. $3 455686
650 2 4 $a Protein Science. $3 376428
650 2 4 $a Molecular Medicine. $3 273932
700 1 $a Chien, Shu. $3 247862
700 1 $a Engler, Adam J. $3 758018
700 1 $a Wang, Peter Yingxiao. $3 758019
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
830 0 $a Physiology in health and disease. $3 730836
856 4 0 $u http://dx.doi.org/10.1007/978-1-4939-5617-3
950 $a Biomedical and Life Sciences (Springer-11642)