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Interleukin 12antitumor activity and...

Lasek, Witold.

Interleukin 12antitumor activity and immunotherapeutic potential in oncology /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Interleukin 12by Witold Lasek, Radoslaw Zagozdzon.
Reminder of title:	antitumor activity and immunotherapeutic potential in oncology /
Author:	Lasek, Witold.
other author:	Zagozdzon, Radoslaw.
Published:	Cham :Springer International Publishing :2016.
Description:	vii, 75 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Interleukin-12.
Online resource:	http://dx.doi.org/10.1007/978-3-319-46906-5
ISBN:	9783319469065$q(electronic bk.)

Interleukin 12antitumor activity and immunotherapeutic potential in oncology /
Lasek, Witold.

Interleukin 12antitumor activity and immunotherapeutic potential in oncology /[electronic resource] :by Witold Lasek, Radoslaw Zagozdzon. - Cham :Springer International Publishing :2016. - vii, 75 p. :ill., digital ;24 cm. - SpringerBriefs in immunology,2194-2773. - SpringerBriefs in immunology..

This book discusses the immunotherapeutic potential of Interleukin 12 in the context of clinical oncology, as well as antitumor effects confirmed in preclinical studies and clinical trials in cancer immunotherapy. Due to its ability to activate both innate (NK cells) and adaptive (cytotoxic T lymphocytes) immunities, Interleukin 12 (IL-12) has been regarded as a promising candidate for tumor immunotherapy. However, despite the encouraging results in animal models, only very modest antitumor effects have been confirmed in early clinical trials. Recently, several clinical studies have been initiated in which IL-12 was applied as an adjuvant in cancer vaccines, in gene therapy including locoregional injections of IL-12 plasmid, and in the form of tumor-targeting immunocytokines (IL-12 fused to monoclonal antibodies)

ISBN: 9783319469065$q(electronic bk.)

Standard No.: 10.1007/978-3-319-46906-5doiSubjects--Topical Terms:

759771
Interleukin-12.

LC Class. No.: QR185.8.I56

Dewey Class. No.: 616.079

Interleukin 12antitumor activity and immunotherapeutic potential in oncology /
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