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Capillary electrophoresis-mass spectrometrytherapeutic protein characterization /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Capillary electrophoresis-mass spectrometryedited by James Q. Xia, Lichao Zhang.
Reminder of title:	therapeutic protein characterization /
other author:	Xia, James Q.
Published:	Cham :Springer International Publishing :2016.
Description:	ix, 74 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Mass spectrometry.
Online resource:	http://dx.doi.org/10.1007/978-3-319-46240-0
ISBN:	9783319462400$q(electronic bk.)

Capillary electrophoresis-mass spectrometrytherapeutic protein characterization /
Capillary electrophoresis-mass spectrometrytherapeutic protein characterization /[electronic resource] :edited by James Q. Xia, Lichao Zhang. - Cham :Springer International Publishing :2016. - ix, 74 p. :ill., digital ;24 cm.

Introduction to Capillary Electrophoresis-Mass Spectrometry -- Coated Capillaries for CE-MS of Therapeutic Protein -- Intact Mass Analysis of Monoclonal Antibodies by Capillary Electrophoresis-Mass Spectrometry -- Separation and Characterization of Proteins and Peptides in Biological Fluids using CE-MS -- Host Cell Protein Analysis using CE-MS -- Antibody PTM Analysis using CE-MS -- Characterization of Intact Therapeutic Proteins and Protein Subunits using CE-MS Platform.

This book covers the latest developments in capillary electrophoresis-mass spectrometry for the analysis of therapeutic proteins. The application of capillary electrophoresis-mass spectrometry (CE-MS) coupling technology in the analysis of recombinant therapeutic proteins is detailed thoroughly. Specific topics include recent developments in coupling capillary electrophoresis with mass spectrometry for the quality control of monoclonal antibody therapeutics, top-down analysis of monoclonal antibody using the CE-MS platform, and detection of host cell protein impurities. Comprehensive characterization of antibody-drug conjugates (ADCs) by coupling capillary electrophoresis with mass spectrometry is also covered. This is an ideal book for scientists in the life science and biopharmaceutical industry who are working on characterizing the PTMs of monoclonal antibodies, as well as graduate students and researchers in the separation science and biological mass spectrometry fields.

ISBN: 9783319462400$q(electronic bk.)

Standard No.: 10.1007/978-3-319-46240-0doiSubjects--Topical Terms:

194021
Mass spectrometry.

LC Class. No.: QP519.9.M3

Dewey Class. No.: 543.65

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245 0 0 $a Capillary electrophoresis-mass spectrometry $h [electronic resource] : $b therapeutic protein characterization / $c edited by James Q. Xia, Lichao Zhang.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2016.
300 $a ix, 74 p. : $b ill., digital ; $c 24 cm.
505 0 $a Introduction to Capillary Electrophoresis-Mass Spectrometry -- Coated Capillaries for CE-MS of Therapeutic Protein -- Intact Mass Analysis of Monoclonal Antibodies by Capillary Electrophoresis-Mass Spectrometry -- Separation and Characterization of Proteins and Peptides in Biological Fluids using CE-MS -- Host Cell Protein Analysis using CE-MS -- Antibody PTM Analysis using CE-MS -- Characterization of Intact Therapeutic Proteins and Protein Subunits using CE-MS Platform.
520 $a This book covers the latest developments in capillary electrophoresis-mass spectrometry for the analysis of therapeutic proteins. The application of capillary electrophoresis-mass spectrometry (CE-MS) coupling technology in the analysis of recombinant therapeutic proteins is detailed thoroughly. Specific topics include recent developments in coupling capillary electrophoresis with mass spectrometry for the quality control of monoclonal antibody therapeutics, top-down analysis of monoclonal antibody using the CE-MS platform, and detection of host cell protein impurities. Comprehensive characterization of antibody-drug conjugates (ADCs) by coupling capillary electrophoresis with mass spectrometry is also covered. This is an ideal book for scientists in the life science and biopharmaceutical industry who are working on characterizing the PTMs of monoclonal antibodies, as well as graduate students and researchers in the separation science and biological mass spectrometry fields.
650 0 $a Mass spectrometry. $3 194021
650 0 $a Capillary electrophoresis. $3 192810
650 0 $a Proteins $x Spectra. $3 224961
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650 2 4 $a Protein Science. $3 376428
650 2 4 $a Mass Spectrometry. $3 344070
650 2 4 $a Spectroscopy and Microscopy. $3 376485
700 1 $a Xia, James Q. $3 762682
700 1 $a Zhang, Lichao. $3 762683
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-46240-0
950 $a Biomedical and Life Sciences (Springer-11642)