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Resistance to targeted therapies against adult brain cancers

Record Type:	Electronic resources : Monograph/item
Title/Author:	Resistance to targeted therapies against adult brain cancersedited by Amanda Tivnan.
other author:	Tivnan, Amanda.
Published:	Cham :Springer International Publishing :2016.
Description:	xvi, 260 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	BrainCancer
Online resource:	http://dx.doi.org/10.1007/978-3-319-46505-0
ISBN:	9783319465050$q(electronic bk.)

Resistance to targeted therapies against adult brain cancers
Resistance to targeted therapies against adult brain cancers[electronic resource] /edited by Amanda Tivnan. - Cham :Springer International Publishing :2016. - xvi, 260 p. :ill., digital ;24 cm. - Resistance to targeted anti-cancer therapeutics,v.112196-5501 ;. - Resistance to targeted anti-cancer therapeutics ;v.4..

Targeted therapies in gliomas: An overview -- Targeting chemotherapy resistance in glioblastoma through modulation of ABC transporters -- Resistance of Glioblastomas to Radiation Therapy -- The blood-brain barrier in glioblastoma multiforme: Pathology and therapeutic implications -- Resistance of brain tumours to small-molecule targeted therapies: lessons from various cancer types -- Drug repurposing to circumvent chemotherapy resistance in brain tumours -- Small molecule inhibitors in glioblastoma: Key pathways and resistance mechanisms -- Imaging Targeted Therapy Response and Resistance in Glioblastoma -- Drug Resistance in Malignant Meningiomas -- Recurrence of Low-Grade Glioma - Have the Targeted Therapies Improved for Better Outcomes? -- Host-Tumor Interactions in Brain Cancer Metastasis Leading to Drug Resistance.

This volume will bring together a review of research being carried out by international experts in this field, detailing treatment and research approaches in several forms of malignant brain tumors. These include glioblastoma (GBM), a highly aggressive and fatal form of astrocytoma which accounts for 80% of newly diagnosed brain tumor patients per year, and meningioma, of which 10% are malignant and extremely resistant to targeted therapies. The volume will also include a discussion of methods to overcome blood-brain barrier exclusion for more efficient targeted drug delivery in all forms of brain cancer treatment. The volume will include information on the repurposing of drugs in an attempt to circumvent drug resistance, use of small molecule inhibitors in GBM treatment, mechanisms of secondary brain metastasis, drug resistance, and state-of-the-art imaging of targeted therapies.

ISBN: 9783319465050$q(electronic bk.)

Standard No.: 10.1007/978-3-319-46505-0doiSubjects--Topical Terms:

745110
Brain
--Cancer

LC Class. No.: RC280.B7

Dewey Class. No.: 616.9948106

Resistance to targeted therapies against adult brain cancers
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520 $a This volume will bring together a review of research being carried out by international experts in this field, detailing treatment and research approaches in several forms of malignant brain tumors. These include glioblastoma (GBM), a highly aggressive and fatal form of astrocytoma which accounts for 80% of newly diagnosed brain tumor patients per year, and meningioma, of which 10% are malignant and extremely resistant to targeted therapies. The volume will also include a discussion of methods to overcome blood-brain barrier exclusion for more efficient targeted drug delivery in all forms of brain cancer treatment. The volume will include information on the repurposing of drugs in an attempt to circumvent drug resistance, use of small molecule inhibitors in GBM treatment, mechanisms of secondary brain metastasis, drug resistance, and state-of-the-art imaging of targeted therapies.
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