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Ex vivo engineering of the tumor mic...

Aref, Amir R.

Ex vivo engineering of the tumor microenvironment

Record Type:	Electronic resources : Monograph/item
Title/Author:	Ex vivo engineering of the tumor microenvironmentedited by Amir R. Aref, David Barbie.
other author:	Aref, Amir R.
Published:	Cham :Springer International Publishing :2017.
Description:	ix, 135 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	CancerMolecular aspects.
Online resource:	http://dx.doi.org/10.1007/978-3-319-45397-2
ISBN:	9783319453972$q(electronic bk.)

Ex vivo engineering of the tumor microenvironment
Ex vivo engineering of the tumor microenvironment[electronic resource] /edited by Amir R. Aref, David Barbie. - Cham :Springer International Publishing :2017. - ix, 135 p. :ill., digital ;24 cm. - Cancer drug discovery and development,2196-9906. - Cancer drug discovery and development..

1.Introduction to Ex Vivo Cancer Models -- 2.Patient-derived Xenografts in Oncology -- 3.Organoid Culture: Applications in Development and Cancer -- 4. Microfluidics and future of cancer diagnostics -- 5.Advancing techniques and insights in circulating tumor cell (CTC) research -- 6.The Cancer Secretome -- 7.An overview of the tumor microenvironments and future of cancer therapy.

This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.

ISBN: 9783319453972$q(electronic bk.)

Standard No.: 10.1007/978-3-319-45397-2doiSubjects--Topical Terms:

221221
Cancer
--Molecular aspects.

LC Class. No.: RC268.4

Dewey Class. No.: 616.994

Ex vivo engineering of the tumor microenvironment
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245 0 0 $a Ex vivo engineering of the tumor microenvironment $h [electronic resource] / $c edited by Amir R. Aref, David Barbie.
260 $a Cham : $b Springer International Publishing : $b Imprint: Humana Press, $c 2017.
300 $a ix, 135 p. : $b ill., digital ; $c 24 cm.
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505 0 $a 1.Introduction to Ex Vivo Cancer Models -- 2.Patient-derived Xenografts in Oncology -- 3.Organoid Culture: Applications in Development and Cancer -- 4. Microfluidics and future of cancer diagnostics -- 5.Advancing techniques and insights in circulating tumor cell (CTC) research -- 6.The Cancer Secretome -- 7.An overview of the tumor microenvironments and future of cancer therapy.
520 $a This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.
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650 1 4 $a Biomedicine. $3 273648
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