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Biliary diseasefrom science to clinic /

Adams, David.

Biliary diseasefrom science to clinic /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Biliary diseaseedited by Gideon Hirschfield, David Adams, Evaggelia Liaskou.
Reminder of title:	from science to clinic /
other author:	Hirschfield, Gideon.
Published:	Cham :Springer International Publishing :2017.
Description:	viii, 264 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Biliary tractDiseases.
Online resource:	http://dx.doi.org/10.1007/978-3-319-50168-0
ISBN:	9783319501680$q(electronic bk.)

Biliary diseasefrom science to clinic /
Biliary diseasefrom science to clinic /[electronic resource] :edited by Gideon Hirschfield, David Adams, Evaggelia Liaskou. - Cham :Springer International Publishing :2017. - viii, 264 p. :ill., digital ;24 cm.

The clinical burden of biliary disease- a global perspective -- The healthy biliary tree- cellular and immunobiology -- Bile acid signalling and the current understanding of cholestasis: new opportunities for treatments? -- Animal models of biliary disease- current approaches and limitations -- The microbiome and human disease- a new organ of interest in biliary disease? -- Progressive familial intrahepatic cholestatic syndromes- genetic insights into biliary transporter function -- Biliary atresia- from pathology to treatment -- Drug induced cholestasis: mechanisms and importance -- Primary biliary cirrhosis- it's science and practice -- Primary sclerosing cholangitis- current concepts in biology and strategies for new therapy -- Cholangiocarcinoma- evaluation of risk and new treatment paradigms -- Gallstone disease in the 21st century: practice and controversies -- Autoimmune sclerosing cholangitis/IgG4 cholangiopathy- new diseases? -- Conclusions and future opportunities.

This book addresses the current understanding of the diagnosis and management of biliary disease across all ages, with emphasis on how the latest advances in clinical science may be integrated into current and future therapies. The coverage is wide ranging, encompassing congenital and acquired conditions including cholestatic syndromes, biliary atresia, drug-induced cholestasis, primary biliary cholangitis/cirrhosis, primary sclerosing cholangitis, cholangiocarcinoma, gallstone disease, and autoimmune sclerosing cholangitis. With contributions from basic and clinical scientists, the relevance of state-of-the-art mechanistic biology to diagnosis, treatment, and future opportunities for drug design is clearly explained. The balance between science and clinical practice will ensure that this book makes a lasting contribution to the field. A broad readership will find the book easy to access and a rich source of information on current best practice and evolving management strategies.

ISBN: 9783319501680$q(electronic bk.)

Standard No.: 10.1007/978-3-319-50168-0doiSubjects--Topical Terms:

308856
Biliary tract
--Diseases.

LC Class. No.: RC845

Dewey Class. No.: 616.36

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245 0 0 $a Biliary disease $h [electronic resource] : $b from science to clinic / $c edited by Gideon Hirschfield, David Adams, Evaggelia Liaskou.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2017.
300 $a viii, 264 p. : $b ill., digital ; $c 24 cm.
505 0 $a The clinical burden of biliary disease- a global perspective -- The healthy biliary tree- cellular and immunobiology -- Bile acid signalling and the current understanding of cholestasis: new opportunities for treatments? -- Animal models of biliary disease- current approaches and limitations -- The microbiome and human disease- a new organ of interest in biliary disease? -- Progressive familial intrahepatic cholestatic syndromes- genetic insights into biliary transporter function -- Biliary atresia- from pathology to treatment -- Drug induced cholestasis: mechanisms and importance -- Primary biliary cirrhosis- it's science and practice -- Primary sclerosing cholangitis- current concepts in biology and strategies for new therapy -- Cholangiocarcinoma- evaluation of risk and new treatment paradigms -- Gallstone disease in the 21st century: practice and controversies -- Autoimmune sclerosing cholangitis/IgG4 cholangiopathy- new diseases? -- Conclusions and future opportunities.
520 $a This book addresses the current understanding of the diagnosis and management of biliary disease across all ages, with emphasis on how the latest advances in clinical science may be integrated into current and future therapies. The coverage is wide ranging, encompassing congenital and acquired conditions including cholestatic syndromes, biliary atresia, drug-induced cholestasis, primary biliary cholangitis/cirrhosis, primary sclerosing cholangitis, cholangiocarcinoma, gallstone disease, and autoimmune sclerosing cholangitis. With contributions from basic and clinical scientists, the relevance of state-of-the-art mechanistic biology to diagnosis, treatment, and future opportunities for drug design is clearly explained. The balance between science and clinical practice will ensure that this book makes a lasting contribution to the field. A broad readership will find the book easy to access and a rich source of information on current best practice and evolving management strategies.
650 0 $a Biliary tract $x Diseases. $3 308856
650 1 4 $a Medicine & Public Health. $3 273799
650 2 4 $a Gastroenterology. $3 274091
650 2 4 $a Hepatology. $3 274979
650 2 4 $a Pediatrics. $3 274247
650 2 4 $a Nursing. $3 204766
650 2 4 $a Pathology. $3 196513
650 2 4 $a Imaging / Radiology. $3 274007
700 1 $a Hirschfield, Gideon. $3 774340
700 1 $a Adams, David. $3 774341
700 1 $a Liaskou, Evaggelia. $3 774342
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773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-50168-0
950 $a Medicine (Springer-11650)