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Proteomic methods in neuropsychiatri...

Guest, Paul C.

Proteomic methods in neuropsychiatric research

Record Type:	Electronic resources : Monograph/item
Title/Author:	Proteomic methods in neuropsychiatric researchedited by Paul C. Guest.
other author:	Guest, Paul C.
Published:	Cham :Springer International Publishing :2017.
Description:	xii, 370 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	NeuropsychiatryResearch
Online resource:	http://dx.doi.org/10.1007/978-3-319-52479-5
ISBN:	9783319524795$q(electronic bk.)

Proteomic methods in neuropsychiatric research
Proteomic methods in neuropsychiatric research[electronic resource] /edited by Paul C. Guest. - Cham :Springer International Publishing :2017. - xii, 370 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology. Proteomics, metabolomics, interactomics and systems biology,9740065-2598 ;. - Advances in experimental medicine and biology.Proteomics, metabolomics, interactomics and systems biology ;974..

Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical management as well as for the development of new drugs by struggling pharmaceutical companies. This book describes the step-by-step use of proteomic methods such as two-dimensional gel electrophoresis, multiplex immunoassay, liquid chromatography mass spectrometry (LC-MS) and selective reaction monitoring MS, to increase our understanding of these diseases, with the ultimate aim of improving patient care. The volume will be of high interest to clinical scientists, physicians and pharmaceutical company scientists as it gives insights into the latest technologies enabling the revolution of personalized medicine. It is of direct interest to both technical and bench biomarker scientists as it gives step by step instructions on how to carry out each of the protocols. It is also of interest to researchers as each technique will be presented in the context of a specific neurological disorder, including Alzheimer's disease, multiple sclerosis, autism spectrum disorders, schizophrenia, major depressive disorder and bipolar disorder. Finally, it will also highlight the future research efforts in this field, which are endeavoring to convert proteomic platforms to the form of hand held devices which can be used in a point of care setting and return diagnostic results within the timeframe of a visit to the general practitioner.

ISBN: 9783319524795$q(electronic bk.)

Standard No.: 10.1007/978-3-319-52479-5doiSubjects--Topical Terms:

775181
Neuropsychiatry
--Research

LC Class. No.: RC337

Dewey Class. No.: 616.890072

Proteomic methods in neuropsychiatric research
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245 0 0 $a Proteomic methods in neuropsychiatric research $h [electronic resource] / $c edited by Paul C. Guest.
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300 $a xii, 370 p. : $b ill., digital ; $c 24 cm.
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520 $a Due to continuous technical developments and new insights into the high complexity of neurological diseases, there is an increasing need for the application of proteomic technologies which can yield potential biomarker readouts for improved clinical management as well as for the development of new drugs by struggling pharmaceutical companies. This book describes the step-by-step use of proteomic methods such as two-dimensional gel electrophoresis, multiplex immunoassay, liquid chromatography mass spectrometry (LC-MS) and selective reaction monitoring MS, to increase our understanding of these diseases, with the ultimate aim of improving patient care. The volume will be of high interest to clinical scientists, physicians and pharmaceutical company scientists as it gives insights into the latest technologies enabling the revolution of personalized medicine. It is of direct interest to both technical and bench biomarker scientists as it gives step by step instructions on how to carry out each of the protocols. It is also of interest to researchers as each technique will be presented in the context of a specific neurological disorder, including Alzheimer's disease, multiple sclerosis, autism spectrum disorders, schizophrenia, major depressive disorder and bipolar disorder. Finally, it will also highlight the future research efforts in this field, which are endeavoring to convert proteomic platforms to the form of hand held devices which can be used in a point of care setting and return diagnostic results within the timeframe of a visit to the general practitioner.
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