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Computational methods for processing...

Balomenos, Panos.

Computational methods for processing and analysis of biological pathways

Record Type:	Electronic resources : Monograph/item
Title/Author:	Computational methods for processing and analysis of biological pathwaysby Anastasios Bezerianos, Andrei Dragomir, Panos Balomenos.
Author:	Bezerianos, Anastasios.
other author:	Dragomir, Andrei.
Published:	Cham :Springer International Publishing :2017.
Description:	viii, 87 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	DrugsDesign.
Online resource:	http://dx.doi.org/10.1007/978-3-319-53868-6
ISBN:	9783319538686$q(electronic bk.)

Computational methods for processing and analysis of biological pathways
Bezerianos, Anastasios.

Computational methods for processing and analysis of biological pathways[electronic resource] /by Anastasios Bezerianos, Andrei Dragomir, Panos Balomenos. - Cham :Springer International Publishing :2017. - viii, 87 p. :ill., digital ;24 cm. - SpringerBriefs in computer science,2191-5768. - SpringerBriefs in computer science..

Introduction -- Networks and Pathways in Systems Pharmacology -- Time Varying Methods for Pathway and Sub-Pathway Analysis -- Identification of Differentially Expressed Pathways and Sub-Pathways.

This work offers a guided walkthrough of one of the most promising research areas in modern life sciences, enabling a deeper understanding of involved concepts and methodologies via an interdisciplinary view, focusing on both well-established approaches and cutting-edge research. Highlighting what pathway analysis can offer to both the experimentalist and the modeler, the text opens with an introduction to a general methodology that outlines common workflows shared by several methods. This is followed by a review of pathway and sub-pathway based approaches for systems pharmacology. The work then presents an overview of pathway analysis methods developed to model the temporal aspects of drug- or disease-induced perturbations and extract relevant dynamic themes. The text concludes by discussing several state-of-the-art methods in pathway analysis, which address the important problem of identifying differentially expressed pathways and sub-pathways.

ISBN: 9783319538686$q(electronic bk.)

Standard No.: 10.1007/978-3-319-53868-6doiSubjects--Topical Terms:

201742
Drugs
--Design.

LC Class. No.: RS420

Dewey Class. No.: 615.19

Computational methods for processing and analysis of biological pathways
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