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Translating molecules into medicines...

Bhattachar, Shobha N.

Translating molecules into medicinescross-functional integration at the drug discovery-development interface /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Translating molecules into medicinesedited by Shobha N. Bhattachar ... [et al.].
Reminder of title:	cross-functional integration at the drug discovery-development interface /
other author:	Bhattachar, Shobha N.
Published:	Cham :Springer International Publishing :2017.
Description:	xxiv, 461 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Drug development.
Online resource:	http://dx.doi.org/10.1007/978-3-319-50042-3
ISBN:	9783319500423$q(electronic bk.)

Translating molecules into medicinescross-functional integration at the drug discovery-development interface /
Translating molecules into medicinescross-functional integration at the drug discovery-development interface /[electronic resource] :edited by Shobha N. Bhattachar ... [et al.]. - Cham :Springer International Publishing :2017. - xxiv, 461 p. :ill. (some col.), digital ;24 cm. - AAPS advances in the pharmaceutical sciences series,v.252210-7371 ;. - AAPS advances in the pharmaceutical sciences series ;3..

Tackling translational medicine with a focus on the drug discovery development-interface, this book integrates approaches and tactics from multiple disciplines, rather than just the pharmaceutical aspect of the field. The authors of each chapter address the paradox between the molecular understanding of diseases, drug discovery, and drug development. Laying out the detailed trends from various fields, different chapters are dedicated to target engagement, toxicological safety assessments, and the compelling relationship of optimizing early clinical studies with design strategies. The book also highlights the importance of balancing the three pillars: sufficient efficacy, acceptable safety and appropriate pharmacokinetics, all of which are crucial to successful efforts in discovery and development. With discussions regarding the combined approaches of molecular research, personalized medicine, pre-clinical and clinical development, as well as targeted therapies--this compendium is a flexible fit, perfect for professionals in the pharmaceutical industry and related academic fields.

ISBN: 9783319500423$q(electronic bk.)

Standard No.: 10.1007/978-3-319-50042-3doiSubjects--Topical Terms:

190608
Drug development.

LC Class. No.: RM301.25

Dewey Class. No.: 615.19

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