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Perioperative inflammation as trigge...

Demicheli, Romano.

Perioperative inflammation as triggering oigin of metastasis development

Record Type:	Electronic resources : Monograph/item
Title/Author:	Perioperative inflammation as triggering oigin of metastasis developmentedited by Michael W. Retsky, Romano Demicheli.
other author:	Retsky, Michael W.
Published:	Cham :Springer International Publishing :2017.
Description:	xxiii, 236 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	BreastCancer.
Online resource:	http://dx.doi.org/10.1007/978-3-319-57943-6
ISBN:	9783319579436$q(electronic bk.)

Perioperative inflammation as triggering oigin of metastasis development
Perioperative inflammation as triggering oigin of metastasis development[electronic resource] /edited by Michael W. Retsky, Romano Demicheli. - Cham :Springer International Publishing :2017. - xxiii, 236 p. :ill., digital ;24 cm.

The Natural History of Breast Cancer -- Perioperative Inflammation as Triggering Origin of Metastasis Development -- Peri-operative Shift in Angiogenesis-Related Factors in Breast Cancer Patients -- Perioperative Biologic Perturbation and Cancer Surgery: Targeting the adrenergic-inflammatory response and microcirculatory dysregulation -- Circulating tumor cells as predictive marker in metastatic disease -- Randomized Clinical Trials on Breast Cancer in Nigeria and other Developing Countries- Challenges and Constraints -- Do Breast Cancer Patients Benefit from Surgery? Hypotheses, Mathematical Models and False Beliefs -- The impact of wound inflammation on cancer progression; Studies in fish and patients -- Long term consequences of acute inflammation in cancer surgery: New findings and perspectives -- Cancer: Nurture and Nature -- The systemic effects of local treatments (surgery and radiotherapy) of breast cancer.

The book will explain previously unconnected clinical data such as why mammography works better for women age 50-59 than it does for women age 40-49, why adjuvant chemotherapy works best for premenopausal patients with positive lymph nodes, and it may also explain the racial disparity in outcome. In particular, it points to the perioperative period when systemic inflammation persists for a week or so. This can lead to a variety of mechanisms whereby single cancer cells (perhaps from the marrow) begin division and angiogenesis of dormant avascular micrometastases occurs leading to early relapses. With chapters presented from distinguished scientists and physicians in a variety of specialties that relate to and border the effects we present, this volume can be used as a reference for practicing physicians and as a jumping-off point for researchers to explore new therapeutic opportunities.

ISBN: 9783319579436$q(electronic bk.)

Standard No.: 10.1007/978-3-319-57943-6doiSubjects--Topical Terms:

275788
Breast
--Cancer.

LC Class. No.: RC280.B8

Dewey Class. No.: 616.99449

Perioperative inflammation as triggering oigin of metastasis development
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245 0 0 $a Perioperative inflammation as triggering oigin of metastasis development $h [electronic resource] / $c edited by Michael W. Retsky, Romano Demicheli.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2017.
300 $a xxiii, 236 p. : $b ill., digital ; $c 24 cm.
505 0 $a The Natural History of Breast Cancer -- Perioperative Inflammation as Triggering Origin of Metastasis Development -- Peri-operative Shift in Angiogenesis-Related Factors in Breast Cancer Patients -- Perioperative Biologic Perturbation and Cancer Surgery: Targeting the adrenergic-inflammatory response and microcirculatory dysregulation -- Circulating tumor cells as predictive marker in metastatic disease -- Randomized Clinical Trials on Breast Cancer in Nigeria and other Developing Countries- Challenges and Constraints -- Do Breast Cancer Patients Benefit from Surgery? Hypotheses, Mathematical Models and False Beliefs -- The impact of wound inflammation on cancer progression; Studies in fish and patients -- Long term consequences of acute inflammation in cancer surgery: New findings and perspectives -- Cancer: Nurture and Nature -- The systemic effects of local treatments (surgery and radiotherapy) of breast cancer.
520 $a The book will explain previously unconnected clinical data such as why mammography works better for women age 50-59 than it does for women age 40-49, why adjuvant chemotherapy works best for premenopausal patients with positive lymph nodes, and it may also explain the racial disparity in outcome. In particular, it points to the perioperative period when systemic inflammation persists for a week or so. This can lead to a variety of mechanisms whereby single cancer cells (perhaps from the marrow) begin division and angiogenesis of dormant avascular micrometastases occurs leading to early relapses. With chapters presented from distinguished scientists and physicians in a variety of specialties that relate to and border the effects we present, this volume can be used as a reference for practicing physicians and as a jumping-off point for researchers to explore new therapeutic opportunities.
650 0 $a Breast $x Cancer. $3 275788
650 0 $a Breast $x Radiography. $3 404856
650 0 $a Inflammation. $3 250775
650 0 $a Metastasis. $3 345769
650 1 4 $a Biomedicine. $3 273648
650 2 4 $a Cancer Research. $3 273660
700 1 $a Retsky, Michael W. $3 787161
700 1 $a Demicheli, Romano. $3 787162
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-57943-6
950 $a Biomedical and Life Sciences (Springer-11642)