國立高雄大學圖資館 |

Language: English

Back

Synthesis of functionalized organobo...

Kubota, Koji.

Synthesis of functionalized organoboron compounds through copper(I) catalysis

Record Type:	Electronic resources : Monograph/item
Title/Author:	Synthesis of functionalized organoboron compounds through copper(I) catalysisby Koji Kubota.
Author:	Kubota, Koji.
Published:	Singapore :Springer Singapore :2017.
Description:	xiii, 213 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Organoboron compoundsSynthesis.
Online resource:	http://dx.doi.org/10.1007/978-981-10-4935-4
ISBN:	9789811049354$q(electronic bk.)

Synthesis of functionalized organoboron compounds through copper(I) catalysis
Kubota, Koji.

Synthesis of functionalized organoboron compounds through copper(I) catalysis[electronic resource] /by Koji Kubota. - Singapore :Springer Singapore :2017. - xiii, 213 p. :ill., digital ;24 cm. - Springer theses,2190-5053. - Springer theses..

General Introduction -- Copper(I)-Catalyzed Direct Boryl Substitution of Unactivated alkyl Halides -- Copper(I)-Catalyzed Intramolecular Borylative exo-Cyclization of Alkenyl Halides Containing Unactivated Double-Bond -- Copper(I)-Catalyzed Regio- and Enantioselective Monoborylation of Alkenylsilanes -- Copper(I)-Catalyzed Enantioselective Nucleophilic Borylation of Aldehydes -- Computational Insight into the Enantioselective Borylation of Aldehydes Cataluzed by Chiral Bisphosphine Copper(I) Complexes -- Copper(I)-Catalyzed Enantioselective Borylative Dearomatization of Indoles -- Copper(I)-Catalyzed Regio- and Enantioselective Borylation of 1,2-Dihydropyridines -- Summary and Outlook.

This book describes state-of-the-art borylation chemistry using copper(I) catalysis. Enantioselective reactions are included to afford a variety of functionalized, complex organoboronate esters, which will find wide application in asymmetric synthesis, drug discovery, and material science. Organoboron compounds are recognized as useful reagents in organic synthesis; therefore, great effort has been devoted to the development of a simple, mild, and efficient method for their preparation in the past several years. However, the synthesis of functionalized organoboron compounds remains a challenging issue because known reactions often require the use of highly reactive organometallic carbon nucleophiles. This book focuses on conceptually new, formal nucleophilic copper(I)-catalyzed borylation reactions with diboron compounds that show high selectivity and excellent functional group compatibility. Theoretical studies based on density functional theory calculations to understand the reaction mechanisms have also been described. Advances in this novel borylation chemistry will allow the rapid and efficient synthesis of complex molecules with potentially interesting properties in combination with the boron functionalization process.

ISBN: 9789811049354$q(electronic bk.)

Standard No.: 10.1007/978-981-10-4935-4doiSubjects--Topical Terms:

247568
Organoboron compounds
--Synthesis.

LC Class. No.: QD412.B1

Dewey Class. No.: 547.05671

Synthesis of functionalized organoboron compounds through copper(I) catalysis
LDR:02951nmm a2200325 a 4500 001 517608
003 DE-He213
005 20170627152617.0
006 m d
007 cr nn 008maaau
008 180316s2017 si s 0 eng d
020 $a 9789811049354$q(electronic bk.)
020 $a 9789811049347$q(paper)
024 7 $a 10.1007/978-981-10-4935-4 $2 doi
035 $a 978-981-10-4935-4
040 $a GP $c GP
041 0 $a eng
050 4 $a QD412.B1
072 7 $a PNN $2 bicssc
072 7 $a SCI013040 $2 bisacsh
082 0 4 $a 547.05671 $2 23
090 $a QD412.B1 $b K95 2017
100 1 $a Kubota, Koji. $3 787286
245 1 0 $a Synthesis of functionalized organoboron compounds through copper(I) catalysis $h [electronic resource] / $c by Koji Kubota.
260 $a Singapore : $b Springer Singapore : $b Imprint: Springer, $c 2017.
300 $a xiii, 213 p. : $b ill., digital ; $c 24 cm.
490 1 $a Springer theses, $x 2190-5053
505 0 $a General Introduction -- Copper(I)-Catalyzed Direct Boryl Substitution of Unactivated alkyl Halides -- Copper(I)-Catalyzed Intramolecular Borylative exo-Cyclization of Alkenyl Halides Containing Unactivated Double-Bond -- Copper(I)-Catalyzed Regio- and Enantioselective Monoborylation of Alkenylsilanes -- Copper(I)-Catalyzed Enantioselective Nucleophilic Borylation of Aldehydes -- Computational Insight into the Enantioselective Borylation of Aldehydes Cataluzed by Chiral Bisphosphine Copper(I) Complexes -- Copper(I)-Catalyzed Enantioselective Borylative Dearomatization of Indoles -- Copper(I)-Catalyzed Regio- and Enantioselective Borylation of 1,2-Dihydropyridines -- Summary and Outlook.
520 $a This book describes state-of-the-art borylation chemistry using copper(I) catalysis. Enantioselective reactions are included to afford a variety of functionalized, complex organoboronate esters, which will find wide application in asymmetric synthesis, drug discovery, and material science. Organoboron compounds are recognized as useful reagents in organic synthesis; therefore, great effort has been devoted to the development of a simple, mild, and efficient method for their preparation in the past several years. However, the synthesis of functionalized organoboron compounds remains a challenging issue because known reactions often require the use of highly reactive organometallic carbon nucleophiles. This book focuses on conceptually new, formal nucleophilic copper(I)-catalyzed borylation reactions with diboron compounds that show high selectivity and excellent functional group compatibility. Theoretical studies based on density functional theory calculations to understand the reaction mechanisms have also been described. Advances in this novel borylation chemistry will allow the rapid and efficient synthesis of complex molecules with potentially interesting properties in combination with the boron functionalization process.
650 0 $a Organoboron compounds $x Synthesis. $3 247568
650 0 $a Organic compounds $x Synthesis. $3 193643
650 0 $a Copper catalysts. $3 698932
650 0 $a Catalysis. $3 188259
650 1 4 $a Chemistry. $3 188628
650 2 4 $a Organic Chemistry. $3 274120
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
830 0 $a Springer theses. $3 557607
856 4 0 $u http://dx.doi.org/10.1007/978-981-10-4935-4
950 $a Chemistry and Materials Science (Springer-11644)