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Molecules, systems and signaling in ...

Ding, Wen-Xing.

Molecules, systems and signaling in liver injury

Record Type:	Electronic resources : Monograph/item
Title/Author:	Molecules, systems and signaling in liver injuryedited by Wen-Xing Ding, Xiao-Ming Yin.
other author:	Ding, Wen-Xing.
Published:	Cham :Springer International Publishing :2017.
Description:	xv, 290 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Cell death.
Online resource:	http://dx.doi.org/10.1007/978-3-319-58106-4
ISBN:	9783319581064$q(electronic bk.)

Molecules, systems and signaling in liver injury
Molecules, systems and signaling in liver injury[electronic resource] /edited by Wen-Xing Ding, Xiao-Ming Yin. - Cham :Springer International Publishing :2017. - xv, 290 p. :ill., digital ;24 cm. - Cell death in biology and diseases. - Cell death in biology and diseases..

This essential volume presents comprehensive information on cell death and autophagy in liver diseases, including the role and molecular signaling pathways of cell death in alcohol and non-alcoholic fatty liver disease, bile acids, hepatitis C virus and drug-induced liver injury. The book starts with a discussion of lipotoxicity in non-parenchymal cells, followed by a discussion of cell death and autophagy in cholangiocytes, hepatic stellate cells and Kupffer cells in hepatic biliary diseases, fibrosis and liver inflammation. The book also covers Bcl-2 family proteins, beta-catenin and HMGB1 signaling in regulating cell death in the liver as well as mitochondria, ER stress and gut microbiota on liver injury. The Cell Death in Biology and Diseases series has recruited world experts ranging from basic scientists to clinicians on cell death in liver diseases. Likewise the contributors of this volume are leaders in their fields with worldwide expertise and perspective. Molecules, Systems and Signaling in Liver Injury is an essential companion to Hepatocytes and Non-Parenchymal Cells and Diseases. It is beneficial for both clinicians and basic scientists and is relevant to those working on drug discovery for preventing and treating liver diseases by targeting cell death and autophagy pathways.

ISBN: 9783319581064$q(electronic bk.)

Standard No.: 10.1007/978-3-319-58106-4doiSubjects--Topical Terms:

193735
Cell death.

LC Class. No.: RD546

Dewey Class. No.: 617.5562044

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520 $a This essential volume presents comprehensive information on cell death and autophagy in liver diseases, including the role and molecular signaling pathways of cell death in alcohol and non-alcoholic fatty liver disease, bile acids, hepatitis C virus and drug-induced liver injury. The book starts with a discussion of lipotoxicity in non-parenchymal cells, followed by a discussion of cell death and autophagy in cholangiocytes, hepatic stellate cells and Kupffer cells in hepatic biliary diseases, fibrosis and liver inflammation. The book also covers Bcl-2 family proteins, beta-catenin and HMGB1 signaling in regulating cell death in the liver as well as mitochondria, ER stress and gut microbiota on liver injury. The Cell Death in Biology and Diseases series has recruited world experts ranging from basic scientists to clinicians on cell death in liver diseases. Likewise the contributors of this volume are leaders in their fields with worldwide expertise and perspective. Molecules, Systems and Signaling in Liver Injury is an essential companion to Hepatocytes and Non-Parenchymal Cells and Diseases. It is beneficial for both clinicians and basic scientists and is relevant to those working on drug discovery for preventing and treating liver diseases by targeting cell death and autophagy pathways.
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