國立高雄大學圖資館 |

Language: English

Back

Genome editing in neurosciences

Gage, Fred.

Genome editing in neurosciences

Record Type:	Electronic resources : Monograph/item
Title/Author:	Genome editing in neurosciencesedited by Rudolf Jaenisch, Feng Zhang, Fred Gage.
other author:	Jaenisch, Rudolf.
Published:	Cham :Springer International Publishing :2017.
Description:	xi, 123 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Neurogenetics.
Online resource:	http://dx.doi.org/10.1007/978-3-319-60192-2
ISBN:	9783319601922$q(electronic bk.)

Genome editing in neurosciences
Genome editing in neurosciences[electronic resource] /edited by Rudolf Jaenisch, Feng Zhang, Fred Gage. - Cham :Springer International Publishing :2017. - xi, 123 p. :ill., digital ;24 cm. - Research and perspectives in neurosciences,0945-6082. - Research and perspectives in neurosciences..

Introduction -- In vitro modeling of complex neurological diseases -- Aquatic model organisms in neurosciences : the genome editing revolution -- Genome-wide genetic screening in the mammalian CNS -- CRISPR/Cas9-mediated Knockin and Knockout in Zebrafish -- Dissecting the role of synaptic proteins with CRISPR -- Recurrently Breaking Genes in Neural Progenitors: Potential Roles of DNA Breaks in Neuronal Function, Degeneration and Cancer -- Neuroscience research using non-human primate models and genome editing -- Multiscale genome engineering: Genome-wide screens and targeted approaches -- Using Genome Engineering to Understand Huntington's Disease -- Therapeutic gene editing in muscles and muscle stem cells.

Open access.

This book is open access under a CC BY 4.0 license. Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Medecine et Recherche has brought together experts from around the world that are applying genome editing to address important challenges in neuroscience, including basic biology in model organisms that has the power to reveal systems-level insight into how the nervous system develops and functions as well as research focused on understanding and treating human neurological disorders.

ISBN: 9783319601922$q(electronic bk.)

Standard No.: 10.1007/978-3-319-60192-2doiSubjects--Topical Terms:

194455
Neurogenetics.

LC Class. No.: QP356.22

Dewey Class. No.: 572.8

Genome editing in neurosciences
LDR:02545nmm a2200337 a 4500 001 522031
003 DE-He213
005 20170914153634.0
006 m d
007 cr nn 008maaau
008 180521s2017 gw s 0 eng d
020 $a 9783319601922$q(electronic bk.)
020 $a 9783319601915$q(paper)
024 7 $a 10.1007/978-3-319-60192-2 $2 doi
035 $a 978-3-319-60192-2
040 $a GP $c GP
041 0 $a eng
050 4 $a QP356.22
072 7 $a MFN $2 bicssc
072 7 $a MED107000 $2 bisacsh
082 0 4 $a 572.8 $2 23
090 $a QP356.22 $b .G335 2017
245 0 0 $a Genome editing in neurosciences $h [electronic resource] / $c edited by Rudolf Jaenisch, Feng Zhang, Fred Gage.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2017.
300 $a xi, 123 p. : $b ill., digital ; $c 24 cm.
490 1 $a Research and perspectives in neurosciences, $x 0945-6082
505 0 $a Introduction -- In vitro modeling of complex neurological diseases -- Aquatic model organisms in neurosciences : the genome editing revolution -- Genome-wide genetic screening in the mammalian CNS -- CRISPR/Cas9-mediated Knockin and Knockout in Zebrafish -- Dissecting the role of synaptic proteins with CRISPR -- Recurrently Breaking Genes in Neural Progenitors: Potential Roles of DNA Breaks in Neuronal Function, Degeneration and Cancer -- Neuroscience research using non-human primate models and genome editing -- Multiscale genome engineering: Genome-wide screens and targeted approaches -- Using Genome Engineering to Understand Huntington's Disease -- Therapeutic gene editing in muscles and muscle stem cells.
506 $a Open access.
520 $a This book is open access under a CC BY 4.0 license. Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Medecine et Recherche has brought together experts from around the world that are applying genome editing to address important challenges in neuroscience, including basic biology in model organisms that has the power to reveal systems-level insight into how the nervous system develops and functions as well as research focused on understanding and treating human neurological disorders.
650 0 $a Neurogenetics. $3 194455
650 0 $a Genetic engineering. $3 189009
650 0 $a RNA editing. $3 229936
650 1 4 $a Biomedicine. $3 273648
650 2 4 $a Human Genetics. $3 273658
650 2 4 $a Neurosciences. $3 211508
650 2 4 $a Biomedical Engineering/Biotechnology. $3 730838
700 1 $a Jaenisch, Rudolf. $3 792483
700 1 $a Zhang, Feng. $3 719066
700 1 $a Gage, Fred. $3 792484
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
830 0 $a Research and perspectives in neurosciences. $3 585005
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-60192-2
950 $a Biomedical and Life Sciences (Springer-11642)