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Histiocytic disorders

Abla, Oussama.

Histiocytic disorders

Record Type:	Electronic resources : Monograph/item
Title/Author:	Histiocytic disordersedited by Oussama Abla, Gritta Janka.
other author:	Abla, Oussama.
Published:	Cham :Springer International Publishing :2018.
Description:	xii, 392 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Langerhans cells.
Online resource:	http://dx.doi.org/10.1007/978-3-319-59632-7
ISBN:	9783319596327$q(electronic bk.)

Histiocytic disorders
Histiocytic disorders[electronic resource] /edited by Oussama Abla, Gritta Janka. - Cham :Springer International Publishing :2018. - xii, 392 p. :ill., digital ;24 cm.

Pathology of Histiocytic Disorders and Neoplasms and Related Disorders -- Biology and Genomics of LCH and Related Disorders -- Epidemiology and Clinical Manifestations of Langerhans Cell Histiocytosis in Children -- Central Nervous System Langerhans Cell Histiocytosis -- First-line Treatment of Pediatric Langerhans Cell Histiocytosis -- Treatment of Relapsed and Refractory Langerhans Cell Histiocytosis in Children -- Adult Langerhans Cell Histiocytosis -- Late Effects of Langerhans Cell Histiocytosis and the Association of LCH with Malignancy -- Classification, Clinical Manifestations and Diagnostics of HLH -- CNS involvement in HLH (CNS-HLH) -- Genetics and Pathogenesis of Haemophagocytic Lymphohistiocytosis -- Hemophagocytic Lymphohistiocytosis Associated with Malignancies and with Epstein Barr Virus -- Macrophage Activation Syndrome in Rheumatic Diseases (MAS-HLH) -- Treatment of Newly Diagnosed HLH and Refractory Disease -- Hematopoietic Cell Transplantation and Novel Therapies in Hemophagocytic Lymphohistiocytosis -- HLH in Adults -- Juvenile Xanthogranuloma and Related Non-LCH Disorders -- Erdheim-Chester Disease -- Rosai-Dorfman Disease -- Malignant Histiocytoses.

This volume provides a comprehensive and world-class review of the field of histiocytic neoplasms and hemophagocytic lymphohistiocytosis (HLH) It reviews all the advances in the field of histiocytoses during the last ten years, particularly with regards to the genomic findings in LCH and other histiocytic neoplasms and the new suggested classification of the histiocytic disorders. Additionally, it features a state-of-the art update on the most recent treatment strategies for LCH, including the results of the last LCH-III international trial, salvage therapies such as reduced-intensity conditioning (RIC) stem cell transplant (SCT), and targeted therapies with BRAF and MEK inhibitors, as well as the challenging cases of CNS-neurodegenerative LCH and its therapeutic perspectives. For primary and secondary HLH the book updates the most recent genetic and pathophysiological findings, including macrophage-activation syndrome (MAS), and includes a special chapter on HLH in adults. Treatment chapters encompass therapy for newly diagnosed HLH and refractory disease as well as stem-cell transplantation and novel therapies. The text also highlights the most recent advances in the treatment of the uncommon histiocytic disorders, such as Erdheim-Chester disease (ECD), Juvenile xanthogranuloma (JXG) and JXG-like conditions, Rosai-Dorfman disease (RDD), and the very rare malignant histiocytoses. Written by international experts in the field, Histiocytic Disorders is a valuable resource for clinicians, researchers, fellows and residents who are interested in or manage histiocytic disorders in children and adults.

ISBN: 9783319596327$q(electronic bk.)

Standard No.: 10.1007/978-3-319-59632-7doiSubjects--Topical Terms:

802620
Langerhans cells.

LC Class. No.: QR185.8.M3

Dewey Class. No.: 616.07995

Histiocytic disorders
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245 0 0 $a Histiocytic disorders $h [electronic resource] / $c edited by Oussama Abla, Gritta Janka.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2018.
300 $a xii, 392 p. : $b ill., digital ; $c 24 cm.
505 0 $a Pathology of Histiocytic Disorders and Neoplasms and Related Disorders -- Biology and Genomics of LCH and Related Disorders -- Epidemiology and Clinical Manifestations of Langerhans Cell Histiocytosis in Children -- Central Nervous System Langerhans Cell Histiocytosis -- First-line Treatment of Pediatric Langerhans Cell Histiocytosis -- Treatment of Relapsed and Refractory Langerhans Cell Histiocytosis in Children -- Adult Langerhans Cell Histiocytosis -- Late Effects of Langerhans Cell Histiocytosis and the Association of LCH with Malignancy -- Classification, Clinical Manifestations and Diagnostics of HLH -- CNS involvement in HLH (CNS-HLH) -- Genetics and Pathogenesis of Haemophagocytic Lymphohistiocytosis -- Hemophagocytic Lymphohistiocytosis Associated with Malignancies and with Epstein Barr Virus -- Macrophage Activation Syndrome in Rheumatic Diseases (MAS-HLH) -- Treatment of Newly Diagnosed HLH and Refractory Disease -- Hematopoietic Cell Transplantation and Novel Therapies in Hemophagocytic Lymphohistiocytosis -- HLH in Adults -- Juvenile Xanthogranuloma and Related Non-LCH Disorders -- Erdheim-Chester Disease -- Rosai-Dorfman Disease -- Malignant Histiocytoses.
520 $a This volume provides a comprehensive and world-class review of the field of histiocytic neoplasms and hemophagocytic lymphohistiocytosis (HLH) It reviews all the advances in the field of histiocytoses during the last ten years, particularly with regards to the genomic findings in LCH and other histiocytic neoplasms and the new suggested classification of the histiocytic disorders. Additionally, it features a state-of-the art update on the most recent treatment strategies for LCH, including the results of the last LCH-III international trial, salvage therapies such as reduced-intensity conditioning (RIC) stem cell transplant (SCT), and targeted therapies with BRAF and MEK inhibitors, as well as the challenging cases of CNS-neurodegenerative LCH and its therapeutic perspectives. For primary and secondary HLH the book updates the most recent genetic and pathophysiological findings, including macrophage-activation syndrome (MAS), and includes a special chapter on HLH in adults. Treatment chapters encompass therapy for newly diagnosed HLH and refractory disease as well as stem-cell transplantation and novel therapies. The text also highlights the most recent advances in the treatment of the uncommon histiocytic disorders, such as Erdheim-Chester disease (ECD), Juvenile xanthogranuloma (JXG) and JXG-like conditions, Rosai-Dorfman disease (RDD), and the very rare malignant histiocytoses. Written by international experts in the field, Histiocytic Disorders is a valuable resource for clinicians, researchers, fellows and residents who are interested in or manage histiocytic disorders in children and adults.
650 0 $a Langerhans cells. $3 802620
650 0 $a Macrophages. $3 467730
650 0 $a Lymphatics $x Diseases. $3 677574
650 0 $a Blood $x Diseases. $3 318459
650 0 $a Immunologic diseases. $3 229419
650 1 4 $a Medicine & Public Health. $3 273799
650 2 4 $a Hematology. $3 274899
650 2 4 $a Oncology. $3 195181
650 2 4 $a Pathology. $3 196513
700 1 $a Abla, Oussama. $3 802618
700 1 $a Janka, Gritta. $3 802619
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-59632-7
950 $a Medicine (Springer-11650)