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Amorphous drugsbenefits and challenges /

Rams-Baron, Marzena.

Amorphous drugsbenefits and challenges /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Amorphous drugsby Marzena Rams-Baron ... [et al.].
Reminder of title:	benefits and challenges /
other author:	Rams-Baron, Marzena.
Published:	Cham :Springer International Publishing :2018.
Description:	ix, 230 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Drug development.
Online resource:	http://dx.doi.org/10.1007/978-3-319-72002-9
ISBN:	9783319720029$q(electronic bk.)

Amorphous drugsbenefits and challenges /
Amorphous drugsbenefits and challenges /[electronic resource] :by Marzena Rams-Baron ... [et al.]. - Cham :Springer International Publishing :2018. - ix, 230 p. :ill., digital ;24 cm.

Why amorphous drugs? -- Order vs. disorder in the solid state -- Amorphous drug solubility and absorption enhancement -- Amorphous drug preparation methods -- Physical instability - a key problem of amorphous drugs -- Amorphous drug formulation.

This book explains theoretical and technological aspects of amorphous drug formulations. It is intended for all those wishing to increase their knowledge in the field of amorphous pharmaceuticals. Conversion of crystalline material into the amorphous state, as described in this book, is a way to overcome limited water solubility of drug formulations, in this way enhancing the chemical activity and bioavailability inside the body. Written by experts from various fields and backgrounds, the book introduces to fundamental physical aspects (explaining differences between the ordered and the disordered solid states, the enhancement of solubility resulting from drugs amorphization, physical instability and how it can be overcome) as well as preparation and formulation procedures to produce and stabilize amorphous pharmaceuticals. Readers will thus gain a well-funded understanding and find a multi-faceted discussion of the properties and advantages of amorphous drugs and of the challenges in producing and stabilizing them. The book is an ideal source of information for researchers and students as well as professionals engaged in research and development of amorphous pharmaceutical products.

ISBN: 9783319720029$q(electronic bk.)

Standard No.: 10.1007/978-3-319-72002-9doiSubjects--Topical Terms:

190608
Drug development.

LC Class. No.: RM301.25

Dewey Class. No.: 615.19

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245 0 0 $a Amorphous drugs $h [electronic resource] : $b benefits and challenges / $c by Marzena Rams-Baron ... [et al.].
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2018.
300 $a ix, 230 p. : $b ill., digital ; $c 24 cm.
505 0 $a Why amorphous drugs? -- Order vs. disorder in the solid state -- Amorphous drug solubility and absorption enhancement -- Amorphous drug preparation methods -- Physical instability - a key problem of amorphous drugs -- Amorphous drug formulation.
520 $a This book explains theoretical and technological aspects of amorphous drug formulations. It is intended for all those wishing to increase their knowledge in the field of amorphous pharmaceuticals. Conversion of crystalline material into the amorphous state, as described in this book, is a way to overcome limited water solubility of drug formulations, in this way enhancing the chemical activity and bioavailability inside the body. Written by experts from various fields and backgrounds, the book introduces to fundamental physical aspects (explaining differences between the ordered and the disordered solid states, the enhancement of solubility resulting from drugs amorphization, physical instability and how it can be overcome) as well as preparation and formulation procedures to produce and stabilize amorphous pharmaceuticals. Readers will thus gain a well-funded understanding and find a multi-faceted discussion of the properties and advantages of amorphous drugs and of the challenges in producing and stabilizing them. The book is an ideal source of information for researchers and students as well as professionals engaged in research and development of amorphous pharmaceutical products.
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