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Antibody therapysubstitution - immun...

Imbach, Paul.

Antibody therapysubstitution - immunomodulation - monoclonal immunotherapy /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Antibody therapyedited by Paul Imbach.
Reminder of title:	substitution - immunomodulation - monoclonal immunotherapy /
other author:	Imbach, Paul.
Published:	Cham :Springer International Publishing :2018.
Description:	xiv, 363 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	ImmunoglobulinsTherapeutic use.
Online resource:	http://dx.doi.org/10.1007/978-3-319-68038-5
ISBN:	9783319680385$q(electronic bk.)

Antibody therapysubstitution - immunomodulation - monoclonal immunotherapy /
Antibody therapysubstitution - immunomodulation - monoclonal immunotherapy /[electronic resource] :edited by Paul Imbach. - Cham :Springer International Publishing :2018. - xiv, 363 p. :ill., digital ;24 cm.

This practical manual, written by well-known experts, reviews current indications for the use of IgG concentrates and some other modern immunomodulators and provides fundamental information on present-day immunomodulation in patients (and mice) The book opens by tracing the transition from IgG substitution to IgG immunomodulation and providing expert updates on immunomodulatory indications in autoimmune and inflammatory disorders, including hematologic, neurologic, dermatologic, and other diseases. Basic aspects of IgG concentrates, including methods of production, safety, currently available products, and mechanisms of action, are then discussed. An entire chapter is devoted to the different aspects of immunomodulatory IgG treatment in the bleeding disorder immune thrombocytopenia (ITP) Finally, the transition from polyclonal to monoclonal antibody (mAb) treatment is addressed in detail, covering mAb development, methods, mechanisms of action, adverse effects, and more. Particular attention is paid to the example of anti-CD20 (B-cell) antibody.

ISBN: 9783319680385$q(electronic bk.)

Standard No.: 10.1007/978-3-319-68038-5doiSubjects--Topical Terms:

274315
Immunoglobulins
--Therapeutic use.

LC Class. No.: QR186.7 / .A585 2018

Dewey Class. No.: 616.0792

Antibody therapysubstitution - immunomodulation - monoclonal immunotherapy /
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