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Protein therapeutics

Jallal, Bahija.

Protein therapeutics

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Protein therapeuticsedited by Tristan Vaughan, Jane Osbourn, and Bahija Jallal.
其他作者:	Vaughan, Tristan.
出版者:	Weinheim, Germany :Wiley-VCH,c2017.
面頁冊數:	1 online resource.
標題:	ProteinsTherapeutic use.
電子資源:	https://onlinelibrary.wiley.com/doi/book/10.1002/9783527699124
ISBN:	9783527699124$q(electronic bk. ;$qoBook)

Protein therapeutics
Protein therapeutics (Wiley-VCH)

Protein therapeutics[electronic resource] /edited by Tristan Vaughan, Jane Osbourn, and Bahija Jallal. - 1st ed. - Weinheim, Germany :Wiley-VCH,c2017. - 1 online resource. - Methods and principles in medicinal chemistry ;v. 71a-71b. - Methods and principles in medicinal chemistry ;v. 39..

Includes bibliographical references and index.

In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades. Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes on to review other key aspects such as pharmacokinetics, safety and immunogenicity, manufacture, formulation and delivery. The handbook then takes a look at current key clinical applications for protein therapeutics, from respiratory and inflammation to oncology and immune-oncology, infectious diseases and rescue therapy. Finally, several exciting prospects for the future of protein therapeutics are highlighted and discussed.

ISBN: 9783527699124$q(electronic bk. ;$qoBook)

Standard No.: 10.1002/9783527699124doiSubjects--Topical Terms:

225255
Proteins
--Therapeutic use.

LC Class. No.: RM666.P87 / P76 2017

Dewey Class. No.: 615.3

Protein therapeutics
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504 $a Includes bibliographical references and index.
520 $a In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades. Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes on to review other key aspects such as pharmacokinetics, safety and immunogenicity, manufacture, formulation and delivery. The handbook then takes a look at current key clinical applications for protein therapeutics, from respiratory and inflammation to oncology and immune-oncology, infectious diseases and rescue therapy. Finally, several exciting prospects for the future of protein therapeutics are highlighted and discussed.
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