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Glucose-sensing receptor in pancreat...

Kojima, Itaru.

Glucose-sensing receptor in pancreatic beta-cells

Record Type:	Electronic resources : Monograph/item
Title/Author:	Glucose-sensing receptor in pancreatic beta-cellsedited by Itaru Kojima.
other author:	Kojima, Itaru.
Published:	Singapore :Springer Singapore :2018.
Description:	v, 71 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	GlucoseReceptors.
Online resource:	http://dx.doi.org/10.1007/978-981-13-0002-8
ISBN:	9789811300028$q(electronic bk.)

Glucose-sensing receptor in pancreatic beta-cells
Glucose-sensing receptor in pancreatic beta-cells[electronic resource] /edited by Itaru Kojima. - Singapore :Springer Singapore :2018. - v, 71 p. :ill., digital ;24 cm.

1 HISTORY OF THE RESEARCH ON THE GLUCOSE RECEPTOR -- 2 Cell-surface Glucoreceptor Recognizing Anomers of Glucose in Pancreatic b-cells -- 3 KATP CHANNEL-INDEPENDENT PATHWAY and THE GLUCORECEPTOR -- 4 Signaling System Activated by the Glucose-sensing Receptor -- 5 The Role of the Glucose-sensing Receptor in Glucose-induced Insulin Secretion in Pancreatic b-cells.

Since the 1970s, there has been much discussion about the "glucoreceptor" and "substrate site" and which of these two is the dominant theory, but new findings on the glucose-sensing receptor have now shed new light on the "glucoreceptor theory." This volume reviews recent advances concerning the glucose-sensing receptor in pancreatic beta-cells. The history of research into pancreatic beta-cells is long and complex; accordingly, the first chapters present the history of this field and explain the hypothesis of insulin secretion mechanisms: "glucoreceptor theory". Subsequent chapters examine the function and activity of the glucose-sensing receptor in pancreatic beta-cells, such as identification, channel pathway, receptor signal and physiological role. Readers will gain a thorough understanding of the glucose-sensing receptor and glucose metabolism in pancreatic beta-cells, new insights into the pathophysiology of diabetes, and learn about new targets for the treatment of diabetes.

ISBN: 9789811300028$q(electronic bk.)

Standard No.: 10.1007/978-981-13-0002-8doiSubjects--Topical Terms:

815615
Glucose
--Receptors.

LC Class. No.: QP702.G56

Dewey Class. No.: 572.565

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505 0 $a 1 HISTORY OF THE RESEARCH ON THE GLUCOSE RECEPTOR -- 2 Cell-surface Glucoreceptor Recognizing Anomers of Glucose in Pancreatic b-cells -- 3 KATP CHANNEL-INDEPENDENT PATHWAY and THE GLUCORECEPTOR -- 4 Signaling System Activated by the Glucose-sensing Receptor -- 5 The Role of the Glucose-sensing Receptor in Glucose-induced Insulin Secretion in Pancreatic b-cells.
520 $a Since the 1970s, there has been much discussion about the "glucoreceptor" and "substrate site" and which of these two is the dominant theory, but new findings on the glucose-sensing receptor have now shed new light on the "glucoreceptor theory." This volume reviews recent advances concerning the glucose-sensing receptor in pancreatic beta-cells. The history of research into pancreatic beta-cells is long and complex; accordingly, the first chapters present the history of this field and explain the hypothesis of insulin secretion mechanisms: "glucoreceptor theory". Subsequent chapters examine the function and activity of the glucose-sensing receptor in pancreatic beta-cells, such as identification, channel pathway, receptor signal and physiological role. Readers will gain a thorough understanding of the glucose-sensing receptor and glucose metabolism in pancreatic beta-cells, new insights into the pathophysiology of diabetes, and learn about new targets for the treatment of diabetes.
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