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The heterogeneity of cancer metabolism

Le, Anne.

The heterogeneity of cancer metabolism

Record Type:	Electronic resources : Monograph/item
Title/Author:	The heterogeneity of cancer metabolismedited by Anne Le.
other author:	Le, Anne.
Published:	Cham :Springer International Publishing :2018.
Description:	xv, 183 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Cancer cellsMetabolism.
Online resource:	http://dx.doi.org/10.1007/978-3-319-77736-8
ISBN:	9783319777368$q(electronic bk.)

The heterogeneity of cancer metabolism
The heterogeneity of cancer metabolism[electronic resource] /edited by Anne Le. - Cham :Springer International Publishing :2018. - xv, 183 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v.10630065-2598 ;. - Advances in experimental medicine and biology ;946..

Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

ISBN: 9783319777368$q(electronic bk.)

Standard No.: 10.1007/978-3-319-77736-8doiSubjects--Topical Terms:

678700
Cancer cells
--Metabolism.

LC Class. No.: RC269.7 / .H484 2018

Dewey Class. No.: 616.99407

The heterogeneity of cancer metabolism
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245 0 4 $a The heterogeneity of cancer metabolism $h [electronic resource] / $c edited by Anne Le.
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300 $a xv, 183 p. : $b ill., digital ; $c 24 cm.
490 1 $a Advances in experimental medicine and biology, $x 0065-2598 ; $v v.1063
520 $a Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
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