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Acute neuronal injurythe role of exc...

Fujikawa, Denson G.

Acute neuronal injurythe role of excitotoxic programmed cell death mechanisms /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Acute neuronal injuryedited by Denson G. Fujikawa.
Reminder of title:	the role of excitotoxic programmed cell death mechanisms /
other author:	Fujikawa, Denson G.
Published:	Cham :Springer International Publishing :2018.
Description:	xii, 215 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Nervous systemDiseases
Online resource:	http://dx.doi.org/10.1007/978-3-319-77495-4
ISBN:	9783319774954$q(electronic bk.)

Acute neuronal injurythe role of excitotoxic programmed cell death mechanisms /
Acute neuronal injurythe role of excitotoxic programmed cell death mechanisms /[electronic resource] :edited by Denson G. Fujikawa. - 2nd ed. - Cham :Springer International Publishing :2018. - xii, 215 p. :ill., digital ;24 cm.

Introduction -- Excitotoxic programmed cell death involves caspase-independent mechanisms -- To survive or to die: how neurons deal with it -- Oxidative damage mechanisms in traumatic brain injury and antioxidant neuroprotective approaches -- Mitochondrial damage in traumatic CNS injury -- Neuroprotective agents target molecular mechanisms of programmed cell death after traumatic brain injury -- Involvement of apoptosis-inducing factor (AIF) in neuronal death following cerebral ischemia -- Apoptosis-inducing factor translocation to nuclei after transient global ischemia -- Necroptosis in cerebral ischemia -- Histological and elemental changes in ischemic stroke -- Hypoglycemic brain damage -- Activation of caspase-independent programmed pathways in seizure-induced neuronal necrosis -- Conclusion.

An overview of the biochemical mechanisms that produce acute nerve cell death in the brain. Covers injuries and disorders including stroke, brain and spinal cord trauma, hypoglycemic coma, and prolonged epileptic seizures. All of these lead to high concentrations of calcium in nerve cells which, in turn, causes degradation of cytoplasmic proteins, cleavage of nuclear DNA, and eventually cell death. The Second Edition contains 11 thoroughly updated chapters and 3 additional chapters that did not appear in the previous edition.

ISBN: 9783319774954$q(electronic bk.)

Standard No.: 10.1007/978-3-319-77495-4doiSubjects--Topical Terms:

455460
Nervous system
--Diseases

LC Class. No.: RC347 / .A288 2018

Dewey Class. No.: 616.807

Acute neuronal injurythe role of excitotoxic programmed cell death mechanisms /
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245 0 0 $a Acute neuronal injury $h [electronic resource] : $b the role of excitotoxic programmed cell death mechanisms / $c edited by Denson G. Fujikawa.
250 $a 2nd ed.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2018.
300 $a xii, 215 p. : $b ill., digital ; $c 24 cm.
505 0 $a Introduction -- Excitotoxic programmed cell death involves caspase-independent mechanisms -- To survive or to die: how neurons deal with it -- Oxidative damage mechanisms in traumatic brain injury and antioxidant neuroprotective approaches -- Mitochondrial damage in traumatic CNS injury -- Neuroprotective agents target molecular mechanisms of programmed cell death after traumatic brain injury -- Involvement of apoptosis-inducing factor (AIF) in neuronal death following cerebral ischemia -- Apoptosis-inducing factor translocation to nuclei after transient global ischemia -- Necroptosis in cerebral ischemia -- Histological and elemental changes in ischemic stroke -- Hypoglycemic brain damage -- Activation of caspase-independent programmed pathways in seizure-induced neuronal necrosis -- Conclusion.
520 $a An overview of the biochemical mechanisms that produce acute nerve cell death in the brain. Covers injuries and disorders including stroke, brain and spinal cord trauma, hypoglycemic coma, and prolonged epileptic seizures. All of these lead to high concentrations of calcium in nerve cells which, in turn, causes degradation of cytoplasmic proteins, cleavage of nuclear DNA, and eventually cell death. The Second Edition contains 11 thoroughly updated chapters and 3 additional chapters that did not appear in the previous edition.
650 0 $a Nervous system $x Diseases $x Cytopathology. $3 455460
650 0 $a Cell death. $3 193735
650 1 4 $a Biomedicine. $3 273648
650 2 4 $a Neurosciences. $3 211508
650 2 4 $a Neurology. $3 211583
650 2 4 $a Pathology. $3 196513
650 2 4 $a Cell Biology. $3 274165
650 2 4 $a Neurobiology. $3 195022
650 2 4 $a Psychiatry. $3 201470
700 1 $a Fujikawa, Denson G. $3 455459
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-77495-4
950 $a Biomedical and Life Sciences (Springer-11642)