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Channelopathies in heart disease

Remme, Carol Ann.

Channelopathies in heart disease

Record Type:	Electronic resources : Monograph/item
Title/Author:	Channelopathies in heart diseaseedited by Dierk Thomas, Carol Ann Remme.
other author:	Thomas, Dierk.
Published:	Cham :Springer International Publishing :2018.
Description:	vi, 437 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Ion channels.
Online resource:	https://doi.org/10.1007/978-3-319-77812-9
ISBN:	9783319778129$q(electronic bk.)

Channelopathies in heart disease
Channelopathies in heart disease[electronic resource] /edited by Dierk Thomas, Carol Ann Remme. - Cham :Springer International Publishing :2018. - vi, 437 p. :ill. (some col.), digital ;24 cm. - Cardiac and vascular biology,2509-7830. - Cardiac and vascular biology..

Introduction -- Part 1: (Dys)function of cardiac ion channels. Cardiac sodium channel (dys)function and inherited arrhythmia syndromes -- Potassium channels in the heart -- Voltage-gated calcium channels and their roles in cardiac electrophysiology -- HCN channels and cardiac pacemaking -- Dysregulation of ionic homeostasis: relevance for cardiac arrhythmias -- Part 2: Cardiac channelopathies: clinical and genetic findings. Long and short QT syndromes -- Brugada syndrome: current perspectives -- Sinus node disease and cardiac conduction disease -- Catecholaminergic polymorphic ventricular tachycardia -- Idiopathic ventricular fibrillation and early repolarization -- Atrial fibrillation -- Genetic testing for inheritable cardiac channelopathies -- Part 3: Research into cardiac channelopathies: new avenues. Novel imaging techniques in cardiac ion channel research -- Transgenic animal models of cardiac channelopathies - benefits and limitations -- Induced pluripotent stem cell-derived cardiomyocytes: towards personalized therapeutic strategies?

This book provides an expert overview on ion channel-related arrhythmia mechanisms, and describes important advances in our understanding of how ion channel dysfunction causes cardiac disease. Both, scientific findings and clinical implications are presented and discussed by scientists who have considerably contributed to the field. The book is organized in three parts: part I treats the molecular and electrophysiological mechanisms of function and dysfunction of ion channels, part II focuses on genetics and clinical findings, whereas part III describes novel research techniques, the use of stem cells and animal models and provides an outlook on future investigations and applications. The book is written for scientists in Cardiovascular Biology and Neuroscience and will be of general interest to Medical Doctors in Cardiology, Cardiac Electrophysiology and related disciplines.

ISBN: 9783319778129$q(electronic bk.)

Standard No.: 10.1007/978-3-319-77812-9doiSubjects--Topical Terms:

195439
Ion channels.

LC Class. No.: RB112.5 / .C436 2018

Dewey Class. No.: 612.015

Channelopathies in heart disease
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245 0 0 $a Channelopathies in heart disease $h [electronic resource] / $c edited by Dierk Thomas, Carol Ann Remme.
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300 $a vi, 437 p. : $b ill. (some col.), digital ; $c 24 cm.
490 1 $a Cardiac and vascular biology, $x 2509-7830
505 0 $a Introduction -- Part 1: (Dys)function of cardiac ion channels. Cardiac sodium channel (dys)function and inherited arrhythmia syndromes -- Potassium channels in the heart -- Voltage-gated calcium channels and their roles in cardiac electrophysiology -- HCN channels and cardiac pacemaking -- Dysregulation of ionic homeostasis: relevance for cardiac arrhythmias -- Part 2: Cardiac channelopathies: clinical and genetic findings. Long and short QT syndromes -- Brugada syndrome: current perspectives -- Sinus node disease and cardiac conduction disease -- Catecholaminergic polymorphic ventricular tachycardia -- Idiopathic ventricular fibrillation and early repolarization -- Atrial fibrillation -- Genetic testing for inheritable cardiac channelopathies -- Part 3: Research into cardiac channelopathies: new avenues. Novel imaging techniques in cardiac ion channel research -- Transgenic animal models of cardiac channelopathies - benefits and limitations -- Induced pluripotent stem cell-derived cardiomyocytes: towards personalized therapeutic strategies?
520 $a This book provides an expert overview on ion channel-related arrhythmia mechanisms, and describes important advances in our understanding of how ion channel dysfunction causes cardiac disease. Both, scientific findings and clinical implications are presented and discussed by scientists who have considerably contributed to the field. The book is organized in three parts: part I treats the molecular and electrophysiological mechanisms of function and dysfunction of ion channels, part II focuses on genetics and clinical findings, whereas part III describes novel research techniques, the use of stem cells and animal models and provides an outlook on future investigations and applications. The book is written for scientists in Cardiovascular Biology and Neuroscience and will be of general interest to Medical Doctors in Cardiology, Cardiac Electrophysiology and related disciplines.
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650 0 $a Pathology, Molecular. $3 194843
650 1 4 $a Biomedical Engineering/Biotechnology. $3 730838
650 2 4 $a Cardiology. $3 273804
650 2 4 $a Regenerative Medicine/Tissue Engineering. $3 675875
650 2 4 $a Cardiovascular Biology. $3 822917
650 2 4 $a Computational Biology/Bioinformatics. $3 274833
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700 1 $a Remme, Carol Ann. $3 822916
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