國立高雄大學圖資館 |

Language: English

Back

Neural control of renal function

Granger, D. Neil,

Neural control of renal function

Record Type:	Electronic resources : Monograph/item
Title/Author:	Neural control of renal functionUlla C. Kopp.
Author:	Kopp, Ulla C.
other author:	Granger, D. Neil,
Published:	San Rafael, California :Morgan & Claypool Life Sciences,2018.
Description:	1 online resource (121 p.)
Subject:	KidneysPhysiology.
Online resource:	click for full text
ISBN:	1615047751

Neural control of renal function
Kopp, Ulla C.

Neural control of renal function[electronic resource] /Ulla C. Kopp. - 2nd ed. - San Rafael, California :Morgan & Claypool Life Sciences,2018. - 1 online resource (121 p.) - Colloquium Series on Integrated Systems Physiology: From Molecule to Function to Disease.. - Colloquium Series on Integrated Systems Physiology : From Molecule to Function to Disease..

Includes bibliographical references and index.

Neural control of renal function, second edition -- Colloquium Digital Library of Life Sciences -- Colloquium Series on Integrated Systems Physiology: From Molecule to Function to Disease -- Abstract -- Contents -- Preface -- Acknowledgments -- Part I. Efferent Renal Sympathetic Nerves -- Chapter 1. Introduction -- Chapter 2. Neuroanatomy -- Chapter 3. Neural Control of Renal Hemodynamics -- Chapter 4. Neural Control of Renal Tubular Function -- Chapter 5. Neural Control of Renin Secretion Rate -- Part II. Afferent Renal Sensory Nerves -- Chapter 6. Introduction -- Chapter 7. Neuroanatomy -- Chapter 8. Renorenal Reflexes -- Chapter 9. Mechanisms Involved in the Activation of Afferent Renal Sensory Nerves -- Chapter 10. Efferent Renal Sympathetic and Afferent Renal Nerves -- Part III. Pathophysiological States -- Chapter 11. Conclusions -- References -- Author Biography.

The kidney is innervated with efferent sympathetic nerve fibers reaching the renal vasculature, the tubules, the juxtaglomerular granular cells, and the renal pelvic wall. The renal sensory nerves are mainly found in the renal pelvic wall. Increases in efferent renal sympathetic nerve activity reduce renal blood flow and urinary sodium excretion by activation of α1-adrenoceptors and increase renin secretion rate by activation of β1-adrenoceptors. In response to normal physiological stimulation, changes in efferent renal sympathetic nerve activity contribute importantly to homeostatic regulation of sodium and water balance. The renal mechanosensory nerves are activated by stretch of the renal pelvic tissue produced by increases in renal pelvic tissue of a magnitude that may occur during increased urine flow rate. Under normal conditions, the renal mechanosensory nerves activated by stretch of the sensory nerves elicits an inhibitory renorenal reflex response consisting of decreases in efferent renal sympathetic nerve activity leading to natriuresis. Increasing efferent sympathetic nerve activity increases afferent renal nerve activity which, in turn, decreases efferent renal sympathetic nerve activity by activation of the renorenal reflexes. Thus, activation of the afferent renal nerves buffers changes in efferent renal sympathetic nerve activity in the overall goal of maintaining sodium balance. In pathological conditions of sodium retention, impairment of the inhibitory renorenal reflexes contributes to an inappropriately increased efferent renal sympathetic nerve activity in the presence of sodium retention. In states of renal disease or injury, there is a shift from inhibitory to excitatory reflexes originating in the kidney. Studies in essential hypertensive patients have shown that renal denervation results in long-term reduction in arterial pressure, suggesting an important role for the efferent and afferent renal nerves in hypertension.

ISBN: 1615047751Subjects--Topical Terms:

504693
Kidneys
--Physiology.

LC Class. No.: QP249

Dewey Class. No.: 617.4610592

Neural control of renal function
LDR:03830nmm a2200301 i 4500 001 559480
006 m o d
007 cr cn|||||||||
008 191226s2018 cau ob 000 0 eng d
020 $a 1615047751
020 $a 161504776X
020 $a 1615047778
020 $a 9781615047758
020 $a 9781615047765
020 $a 9781615047772
035 $a MCPB0006410
040 $a iG Publishing $b eng $e aacr2 $c iG Publishing
041 0 $a eng
050 0 0 $a QP249
082 0 4 $a 617.4610592
100 1 $a Kopp, Ulla C. $3 842620
245 1 0 $a Neural control of renal function $h [electronic resource] / $c Ulla C. Kopp.
250 $a 2nd ed.
260 $a San Rafael, California : $b Morgan & Claypool Life Sciences, $c 2018.
300 $a 1 online resource (121 p.)
490 1 $a Colloquium Series on Integrated Systems Physiology: From Molecule to Function to Disease.
504 $a Includes bibliographical references and index.
505 0 $a Neural control of renal function, second edition -- Colloquium Digital Library of Life Sciences -- Colloquium Series on Integrated Systems Physiology: From Molecule to Function to Disease -- Abstract -- Contents -- Preface -- Acknowledgments -- Part I. Efferent Renal Sympathetic Nerves -- Chapter 1. Introduction -- Chapter 2. Neuroanatomy -- Chapter 3. Neural Control of Renal Hemodynamics -- Chapter 4. Neural Control of Renal Tubular Function -- Chapter 5. Neural Control of Renin Secretion Rate -- Part II. Afferent Renal Sensory Nerves -- Chapter 6. Introduction -- Chapter 7. Neuroanatomy -- Chapter 8. Renorenal Reflexes -- Chapter 9. Mechanisms Involved in the Activation of Afferent Renal Sensory Nerves -- Chapter 10. Efferent Renal Sympathetic and Afferent Renal Nerves -- Part III. Pathophysiological States -- Chapter 11. Conclusions -- References -- Author Biography.
520 3 $a The kidney is innervated with efferent sympathetic nerve fibers reaching the renal vasculature, the tubules, the juxtaglomerular granular cells, and the renal pelvic wall. The renal sensory nerves are mainly found in the renal pelvic wall. Increases in efferent renal sympathetic nerve activity reduce renal blood flow and urinary sodium excretion by activation of α1-adrenoceptors and increase renin secretion rate by activation of β1-adrenoceptors. In response to normal physiological stimulation, changes in efferent renal sympathetic nerve activity contribute importantly to homeostatic regulation of sodium and water balance. The renal mechanosensory nerves are activated by stretch of the renal pelvic tissue produced by increases in renal pelvic tissue of a magnitude that may occur during increased urine flow rate. Under normal conditions, the renal mechanosensory nerves activated by stretch of the sensory nerves elicits an inhibitory renorenal reflex response consisting of decreases in efferent renal sympathetic nerve activity leading to natriuresis. Increasing efferent sympathetic nerve activity increases afferent renal nerve activity which, in turn, decreases efferent renal sympathetic nerve activity by activation of the renorenal reflexes. Thus, activation of the afferent renal nerves buffers changes in efferent renal sympathetic nerve activity in the overall goal of maintaining sodium balance. In pathological conditions of sodium retention, impairment of the inhibitory renorenal reflexes contributes to an inappropriately increased efferent renal sympathetic nerve activity in the presence of sodium retention. In states of renal disease or injury, there is a shift from inhibitory to excitatory reflexes originating in the kidney. Studies in essential hypertensive patients have shown that renal denervation results in long-term reduction in arterial pressure, suggesting an important role for the efferent and afferent renal nerves in hypertension.
650 0 $a Kidneys $x Physiology. $3 504693
650 0 $a Kidneys $x Innervation. $3 842624
650 0 $a Kidneys $x Diseases. $3 318100
650 0 $a Science. $3 177564
650 0 $a Life Sciences. $3 273679
650 0 $a Anatomy & Physiology. $3 842625
700 1 $a Granger, D. Neil, $e editor. $3 842621
700 1 $a Granger, Joey P., $e editor. $3 842622
830 0 $a Colloquium Series on Integrated Systems Physiology : From Molecule to Function to Disease. $3 842623
856 4 0 $u http://portal.igpublish.com/iglibrary/search/MCPB0006410.html $z click for full text