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Viruses :molecular biology, host int...

Fermin, Gustavo,

Viruses :molecular biology, host interactions, and applications to biotechnology /

Record Type:	Electronic resources : Monograph/item
Title/Author:	Viruses :Paula Tennant, Gustavo Fermin, Jerome E. Foster.
Reminder of title:	molecular biology, host interactions, and applications to biotechnology /
Author:	Tennant, Paula,
other author:	Fermin, Gustavo,
Description:	1 online resource
Subject:	Molecular virology.
Online resource:	https://www.sciencedirect.com/science/book/9780128112571
ISBN:	9780128111949$q(electronic bk.)

Viruses :molecular biology, host interactions, and applications to biotechnology /
Tennant, Paula,

Viruses :molecular biology, host interactions, and applications to biotechnology /Paula Tennant, Gustavo Fermin, Jerome E. Foster. - 1 online resource

Includes bibliographical references and index.

Front Cover; Viruses; Copyright Page; Contents; List of Contributors; Preface; 1 Introduction: A Short History of Virology; C332,652H492,388N98,245O131,196P7,501S2,340; From Filterable Agent to Genetic Parasite; Viruses Have Contributed to Our Understanding of a Gene and How It Works; Viruses Have Allowed Us to Understand How Genes Are Regulated; Viruses Have Contributed to Our Understanding of How Genomes Are Organized; Viruses Have Contributed to Our Understanding of the Mechanisms Underlying RNAi; Viruses That Cause Diseases Represent a Small Fraction of the Viral Community.

Viruses: Molecular Biology, Host Interactions, and Applications to Biotechnology provides an up-to-date introduction to human, animal and plant viruses within the context of recent advances in high-throughput sequencing that have demonstrated that viruses are vastly greater and more diverse than previously recognized. It covers discoveries such as the Mimivirus and its virophage which have stimulated new discussions on the definition of viruses, their place in the current view, and their inherent and derived 'interactomics' as defined by the molecules and the processes by which virus gene products interact with themselves and their host's cellular gene products. Further, the book includes perspectives on basic aspects of virology, including the structure of viruses, the organization of their genomes, and basic strategies in replication and expression, emphasizing the diversity and versatility of viruses, how they cause disease and how their hosts react to such disease, and exploring developments in the field of host-microbe interactions in recent years. The book is likely to appeal, and be useful, to a wide audience that includes students, academics and researchers studying the molecular biology and applications of viruses.

ISBN: 9780128111949$q(electronic bk.)Subjects--Topical Terms:

194429
Molecular virology.
Index Terms--Genre/Form:

214472
Electronic books.

LC Class. No.: QR389

Dewey Class. No.: 579.2

Viruses :molecular biology, host interactions, and applications to biotechnology /
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245 1 0 $a Viruses : $b molecular biology, host interactions, and applications to biotechnology / $c Paula Tennant, Gustavo Fermin, Jerome E. Foster.
264 1 $a San Diego, CA : $b Academic Press, $c [2018]
264 4 $c ©2018
300 $a 1 online resource
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504 $a Includes bibliographical references and index.
505 0 $a Front Cover; Viruses; Copyright Page; Contents; List of Contributors; Preface; 1 Introduction: A Short History of Virology; C332,652H492,388N98,245O131,196P7,501S2,340; From Filterable Agent to Genetic Parasite; Viruses Have Contributed to Our Understanding of a Gene and How It Works; Viruses Have Allowed Us to Understand How Genes Are Regulated; Viruses Have Contributed to Our Understanding of How Genomes Are Organized; Viruses Have Contributed to Our Understanding of the Mechanisms Underlying RNAi; Viruses That Cause Diseases Represent a Small Fraction of the Viral Community.
505 8 $a Viruses Can Be Beneficial to Their HostsViruses Can Function as Tools for Biotechnology; Further Reading; 2 Virion Structure, Genome Organization, and Taxonomy of Viruses; What Is a virus?â#x80;#x94;Perhaps There Is a Simple Answer, Not an Easy Answer; Virion Morphologies; Icosahedral/Spherical Virions; Filamentous/Bacilliform Virions; Amazing Forms Among Old and New Comers; Do Viruses Really Need a Coat?; Types and Function of the Virus Envelope; Genomes: The Nucleic Acids Space Exploited by Viruses; dsDNA viruses; ssDNA virusesâ#x80;#x94;No Polarity or Mixed Polarity; ssDNA(â#x88;#x92;) viruses; ssDNA(+) viruses.
505 8 $a SsDNA(+/â#x88;#x92;) virusesdsRNA viruses; ssRNA (Viroids); ssRNA(â#x88;#x92;) viruses; ssRNA(+) viruses; ssRNA(+/â#x88;#x92;) viruses; Virus Taxonomy: Organization of the Vast Diversity Among Viruses; Baltimore Classification; The International Committee on Taxonomy of Viruses; The Goal of Virus Taxonomy; Further Reading; 3 Replication and Expression Strategies of Viruses; Overview of Virus Genome Transcription and Replication; Polymerases; Initiation, Elongation, and Termination; Initiation; Elongation; Termination; Mechanisms of Genome Transcription and Replication; Rolling Circle Replication.
505 8 $a Rolling-Hairpin ReplicationdsDNA Bidirectional Replication; dsDNA (RT) Transcription and Replication; ssRNA (RT) Replication; Positive-Strand RNA Virus Replication; Double-Strand RNA Virus Transcription and Replication; Negative-Strand RNA Virus Transcription and Replication; dsDNA Template Transcription and Replication; Viral Genome Expression; Disruption of Transcription Initiation Complex Assembly; Termini Maturation and Modification; Internal Ribosome Entry; Poly(A) Tailing; RNA Editing; Alternative Splicing; Suppression of Termination; Programmed Ribosomal Frameshifting.
505 8 $a Leaky Scanning and Translation ReinitiationRibosomal Shunting; â#x80;#x9C;2Aâ#x80;#x9D; Oligopeptides and â#x80;#x9C;Stop-Carry Onâ#x80;#x9D; Recoding; Subversion of Host Gene Expression; Inhibition of Cellular RNA Polymerase; Disruption of Cellular mRNA Export Pathways; Decay of Host mRNAs by Viruses; Circumvention of Cellular RNA Decay Machinery; Shutoff of Cellular mRNA Translation; Recruitment of Cellular Hsp70 Chaperones for Viral Protein Folding; Compromising Cellular Lipid Metabolism; Cell Cycle Disruption for Preferential Viral Replication; Virus Genome Replication Complexes; Further reading.
520 $a Viruses: Molecular Biology, Host Interactions, and Applications to Biotechnology provides an up-to-date introduction to human, animal and plant viruses within the context of recent advances in high-throughput sequencing that have demonstrated that viruses are vastly greater and more diverse than previously recognized. It covers discoveries such as the Mimivirus and its virophage which have stimulated new discussions on the definition of viruses, their place in the current view, and their inherent and derived 'interactomics' as defined by the molecules and the processes by which virus gene products interact with themselves and their host's cellular gene products. Further, the book includes perspectives on basic aspects of virology, including the structure of viruses, the organization of their genomes, and basic strategies in replication and expression, emphasizing the diversity and versatility of viruses, how they cause disease and how their hosts react to such disease, and exploring developments in the field of host-microbe interactions in recent years. The book is likely to appeal, and be useful, to a wide audience that includes students, academics and researchers studying the molecular biology and applications of viruses.
650 0 $a Molecular virology. $3 194429
650 0 $a Virus diseases $x Molecular aspects. $3 194431
650 1 2 $a Viruses. $3 194048
655 4 $a Electronic books. $2 local. $3 214472
700 1 $a Fermin, Gustavo, $e author. $3 846263
700 1 $a Foster, Jerome E., $e author. $3 846264
856 4 0 $u https://www.sciencedirect.com/science/book/9780128112571