國立高雄大學圖資館 |

Language: English

Back

Leukemia stem cells in hematologic m...

Li, Shaoguang.

Leukemia stem cells in hematologic malignancies

Record Type:	Electronic resources : Monograph/item
Title/Author:	Leukemia stem cells in hematologic malignanciesedited by Haojian Zhang, Shaoguang Li.
other author:	Zhang, Haojian.
Published:	Singapore :Springer Singapore :2019.
Description:	viii, 229 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer eBooks
Subject:	Leukemia.
Online resource:	https://doi.org/10.1007/978-981-13-7342-8
ISBN:	9789811373428$q(electronic bk.)

Leukemia stem cells in hematologic malignancies
Leukemia stem cells in hematologic malignancies[electronic resource] /edited by Haojian Zhang, Shaoguang Li. - Singapore :Springer Singapore :2019. - viii, 229 p. :ill. (some col.), digital ;24 cm. - Advances in experimental medicine and biology,v.11430065-2598 ;. - Advances in experimental medicine and biology ;946..

Role of leukemia stem cells in pathogenesis of hematologic malignancies -- Leukemia stem cells in chronic myeloid leukemia -- Leukmeia stem cells in MLL-rearranged acute myeloid leukemia -- Interaction between leukmeia stem cells and bone marrow environment -- Molecular signatures of leukemia stem cells -- Metabolic regulation of leukemia stem cell function -- Epigenetic regulation of leukmeia stem cell function -- DNA instability and leukemia stem cell function -- Tumor suppressor genes in leukemia stem cells -- Targeting leukemia stem cells -- Leukemia stem cells and drug resistance -- Hypoxia and leukemia.

This book introduces readers to the biology of leukemia stem cells (LSCs) and emphasizes the necessity and importance of targeting LSCs in the treatment of hematopoietic malignancies. It addresses the role of leukemia stem cells in different leukemia diseases and molecular signatures, as well as the metabolic and epigenetic regulation of leukemia stem cell function. With regard to solid tumors, a significant number of blood cancers are believed to be derived from leukemia stem cells (LSCs), which are responsible for disease progression, relapse and drug resistance. Consequently, new therapeutic strategies need to be developed by focusing on the complete eradication of LSCs. Given its scope, the book offers a valuable asset for graduate students and scientists in the fields of cell biology and cancer research etc.

ISBN: 9789811373428$q(electronic bk.)

Standard No.: 10.1007/978-981-13-7342-8doiSubjects--Topical Terms:

234134
Leukemia.

LC Class. No.: RC643 / .L485 2019

Dewey Class. No.: 616.99419

Leukemia stem cells in hematologic malignancies
LDR:02530nmm a2200337 a 4500 001 563557
003 DE-He213
005 20191127105802.0
006 m d
007 cr nn 008maaau
008 200311s2019 si s 0 eng d
020 $a 9789811373428$q(electronic bk.)
020 $a 9789811373411$q(paper)
024 7 $a 10.1007/978-981-13-7342-8 $2 doi
035 $a 978-981-13-7342-8
040 $a GP $c GP
041 0 $a eng
050 4 $a RC643 $b .L485 2019
072 7 $a MJCL $2 bicssc
072 7 $a MED062000 $2 bisacsh
072 7 $a MJCL $2 thema
082 0 4 $a 616.99419 $2 23
090 $a RC643 $b .L652 2019
245 0 0 $a Leukemia stem cells in hematologic malignancies $h [electronic resource] / $c edited by Haojian Zhang, Shaoguang Li.
260 $a Singapore : $b Springer Singapore : $b Imprint: Springer, $c 2019.
300 $a viii, 229 p. : $b ill. (some col.), digital ; $c 24 cm.
490 1 $a Advances in experimental medicine and biology, $x 0065-2598 ; $v v.1143
505 0 $a Role of leukemia stem cells in pathogenesis of hematologic malignancies -- Leukemia stem cells in chronic myeloid leukemia -- Leukmeia stem cells in MLL-rearranged acute myeloid leukemia -- Interaction between leukmeia stem cells and bone marrow environment -- Molecular signatures of leukemia stem cells -- Metabolic regulation of leukemia stem cell function -- Epigenetic regulation of leukmeia stem cell function -- DNA instability and leukemia stem cell function -- Tumor suppressor genes in leukemia stem cells -- Targeting leukemia stem cells -- Leukemia stem cells and drug resistance -- Hypoxia and leukemia.
520 $a This book introduces readers to the biology of leukemia stem cells (LSCs) and emphasizes the necessity and importance of targeting LSCs in the treatment of hematopoietic malignancies. It addresses the role of leukemia stem cells in different leukemia diseases and molecular signatures, as well as the metabolic and epigenetic regulation of leukemia stem cell function. With regard to solid tumors, a significant number of blood cancers are believed to be derived from leukemia stem cells (LSCs), which are responsible for disease progression, relapse and drug resistance. Consequently, new therapeutic strategies need to be developed by focusing on the complete eradication of LSCs. Given its scope, the book offers a valuable asset for graduate students and scientists in the fields of cell biology and cancer research etc.
650 0 $a Leukemia. $3 234134
650 0 $a Stem cells. $3 200260
650 0 $a Blood $x Diseases. $3 318459
650 1 4 $a Cancer Research. $3 273660
650 2 4 $a Stem Cells. $3 203924
700 1 $a Zhang, Haojian. $3 849188
700 1 $a Li, Shaoguang. $3 309642
710 2 $a SpringerLink (Online service) $3 273601
773 0 $t Springer eBooks
830 0 $a Advances in experimental medicine and biology ; $v 946. $3 557559
856 4 0 $u https://doi.org/10.1007/978-981-13-7342-8
950 $a Biomedical and Life Sciences (Springer-11642)